Preparación de un plausible eje de rotaxano quiral aminoácido-esteroide

Rotaxanes are compounds that are made up of two submolecular components: a cyclic one (a ring) and a linear one (an axis) that threads the previous one and that, in addition, has bulky groups at their ends in order to keep both components intertwined. Another simple tool to keep this type of macrost...

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Detalles Bibliográficos
Autores: Corona Sánchez, Ricardo, Gutiérrez Carrillo, Atilano, García Martínez, Cirilo, Santillán Baca, Rosa Luisa, Sánchez Eleuterio, Alma
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:México
Institución:Universidad Autónoma Metropolitana
Repositorio:Repositorio Institucional Zaloamati
Idioma:español
OAI Identifier:oai:zaloamati.azc.uam.mx:11191/9331
Acceso en línea:http://hdl.handle.net/11191/9331
Access Level:acceso abierto
Palabra clave:Rotaxano, aminoa cido, esteroide. Rotaxane, aminoacid, steroid.
BIOLOGÍA Y QUÍMICA::QUÍMICA::QUÍMICA ORGÁNICA::SÍNTESIS QUÍMICA
Descripción
Sumario:Rotaxanes are compounds that are made up of two submolecular components: a cyclic one (a ring) and a linear one (an axis) that threads the previous one and that, in addition, has bulky groups at their ends in order to keep both components intertwined. Another simple tool to keep this type of macrostructures anchored is through non-covalent bonds such as hydrogen bonds, coordination bonds with metal ions and aromatic π-π interactions, among others. In this work the rapid and quantitative synthesis of a conductive thread (chiral axis) composed of chiral molecules is reported, which give it excellent anchoring properties important for the synthesis of rotaxanes.