Lupus eritematoso: enfermedad autoinmune sistémica y órgano específica

Lupus erythematosus: systemic autoimmune and organ specific disease. The immune system of patients with Lupus becomes activated and reacts against themselves, which is why it is considered an autoimmune disease. In the USA more than one million people have Lupus. The symptoms appear in a variety of...

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Detalles Bibliográficos
Autores: Sánchez Rodríguez, Sergio, Barajas Vásquez, Gerardo, Ramírez Alvarado, Elena, Moreno García, María Alejandra, Barbosa Cisneros, Olga Yadira
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2004
País:México
Institución:Universidad Autónoma de Zacatecas
Repositorio:Repositorio Institucional Caxcán
Idioma:español
OAI Identifier:oai:http://ricaxcan.uaz.edu.mx:20.500.11845/839
Acceso en línea:http://localhost/xmlui/handle/20.500.11845/839
https://doi.org/10.48779/9kgv-qn43
Access Level:acceso abierto
Palabra clave:BIOLOGIA Y QUIMICA [2]
Lupus eritematoso
anticuerpos
autoinmunidad
antígenos
autoanticuerpos
Lupus erythematosus
antibodies
autoimmunity
antigens
autoantibodies
Descripción
Sumario:Lupus erythematosus: systemic autoimmune and organ specific disease. The immune system of patients with Lupus becomes activated and reacts against themselves, which is why it is considered an autoimmune disease. In the USA more than one million people have Lupus. The symptoms appear in a variety of forms, and half of the cases are lethal. The damage may appears in any organ of the body and can cause arthritis with inflammation, fatigue, facial o malar rash, oral ulcers, photosensitivity, serositis (inflammation of tissue around the lung and heart), renal disorders (proteinuria, cellular destruction), blood disorders (leukopenia, lymphopenia, thrombocytopenia, hemolytic anemia), immunological disorders (anti-DNA, anti-Sm antibodies), and abnormal antinuclear antibody titles. Using molecular biology techniques some factors that regulate the immune system and biochemistry mechanisms of tissues damage in lupus have been discovered. In addition some genes that appear to be involved in the generation of lupus have been identified.