Role of Bcl-3 in solid tumors

Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progr...

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Detalles Bibliográficos
Autores: VILMA ARACELI MALDONADO LAGUNAS, JORGE MELÉNDEZ ZAJGLA
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:México
Institución:Instituto Nacional de Medicina Genómica
Repositorio:Repositorio del Instituto Nacional de Medicina Genómica
Idioma:inglés
OAI Identifier:oai:repositorio.inmegen.gob.mx:6
Acceso en línea:http://repositorio.inmegen.gob.mx/record/6
Access Level:acceso abierto
Palabra clave:info:eu-repo/classification/cti/3
Descripción
Sumario:Bcl-3 is an established oncogene in hematologic malignancies, such as B-cell chronic lymphocytic leukemias. Nevertheless, recent research has shown that it also participates in progression of diverse solid tumors. The present review summarizes the current knowledge of Bcl3 role in solid tumors progression, including some new insights in its possible molecular mechanisms of action.