Nanostructured metal-organic frameworks (MOFs) applied to controlled drug delivery

Metal-organics frameworks are coordination polymers constituted of a metallic center and an organic ligand that can be designed using biocompatible metal ions (e.g. Fe+3, Zn+2, Mg+2, Ca+2 y Mo+6) and bioactive organic ligands yielding to the modulation of the structure and properties materials in th...

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Detalles Bibliográficos
Autores: Claudio-Rizo, Jesús A., Cano Salazar, Lucia F., Flores-Guia, Tirso E., Cabrera-Munguia, Denis A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:México
Institución:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO
Repositorio:Mundo Nano. Revista Interdisciplinaria en Nanociencias y Nanotecnología
Idioma:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/69634
Acceso en línea:https://www.mundonano.unam.mx/ojs/index.php/nano/article/view/69634
Access Level:acceso abierto
Palabra clave:MOFs
nanostructure
controlled drug delivery
biocompatibility
nanoestructura
liberación controlada de fármacos
biocompatibilidad
Descripción
Sumario:Metal-organics frameworks are coordination polymers constituted of a metallic center and an organic ligand that can be designed using biocompatible metal ions (e.g. Fe+3, Zn+2, Mg+2, Ca+2 y Mo+6) and bioactive organic ligands yielding to the modulation of the structure and properties materials in the nano scale. The aim of this work is provide an outlook about the materials applied for drug delivery systems, emphasizing the advantages, advances and challenges in the controlled drug delivery using nanostructured MOFs, the delivery mechanism, degradability and antimicrobial activity is also presented.