Renal function in children with obesity and metabolic syndrome

Obesity in Mexico is a Public Health problem. The objective of this study is to evaluate kidney function in obese children with and without metabolic syndrome (MS), in relation to healthy subjects. For this, weight, height, mid-upper arm circumference (MUAC), waist circumference (WC), body surface a...

Descripción completa

Detalles Bibliográficos
Autores: Dubey Ortega, Luis Antonio, Ramírez Miramontes, Julia Verónica, Dubey Malagón, Alejandra, Kornhauser Araujo, Carlos, Puga Rosas, Ángeles
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:México
Institución:UNIVERSIDAD DE GUANAJUATO
Repositorio:Acta Universitaria
Idioma:español
OAI Identifier:oai:www.actauniversitaria.ugto.mx:article/765
Acceso en línea:https://www.actauniversitaria.ugto.mx/index.php/acta/article/view/765
Access Level:acceso abierto
Palabra clave:Obesidad
síndrome metabólico
riñón
hiperfiltración
glomerulopatía por obesidad
tasa de filtración glomerular.
NEFROLOGIA
Obesity
metabolic syndrome
kidney
hiperfiltration
obesity glomerulopaty
glomerular filtration rate.
Descripción
Sumario:Obesity in Mexico is a Public Health problem. The objective of this study is to evaluate kidney function in obese children with and without metabolic syndrome (MS), in relation to healthy subjects. For this, weight, height, mid-upper arm circumference (MUAC), waist circumference (WC), body surface area (BSA), body mass index (BMI), glomerular filtration rate (GFR) (Schwarts) were taken. Glucose, creatinine, uric acid, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), triglycerides and general urine test were taken also. 128 Pediatric patients studied were formed into three groups (healthy, obese with and without MS), with an age of 11.04 ± 2.63 years. Obese males with MS had significant increase in glucose (p = 0.04) and triglycerides (p = 0.0033); obese women had a significant elevation of glucose (p = 0.042) and triglycerides (p = 0.022). The two groups with obesity showed increase in GFR (Hyperfiltration), in comparison to healthy controls. Possible hyperinsulinemia in patients, produces hypertrophy and glomerular hyperfiltration. Obese patients with and without MS, had impaired kidney function.