Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI
Introduction TBI is associated with alterations in cortico-subcortical connectivity. However, little attention has been paid to its clinical characteristics and functional connectivity in pediatric patients with chronic TBI.Objective To evaluate the cognitive performance and spectral coherence of a...
| Autores: | , , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2019 |
| País: | México |
| Recursos: | Universidad Nacional Autónoma de México |
| Repositório: | Redalyc-UNAM |
| OAI Identifier: | oai:redalyc.org:58261085005 |
| Acesso em linha: | https://www.redalyc.org/articulo.oa?id=58261085005 https://www.redalyc.org/journal/582/58261085005/ https://www.redalyc.org/journal/582/58261085005/html/ https://www.redalyc.org/journal/582/58261085005/58261085005.epub https://www.redalyc.org/journal/582/58261085005/movil |
| Access Level: | Acceso aberto |
| Palavra-chave: | Medicina EEG child cognition traumatic brain injury |
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Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBIMarlene Galicia-AlvaradoJavier Alducin-CastilloMaura Jazmín Ramírez-FloresAna Laura Sánchez QuezadaOscar Yáñez-SuárezBlanca Flores-ÁvalosMedicinaEEGchildcognitiontraumatic brain injuryIntroduction TBI is associated with alterations in cortico-subcortical connectivity. However, little attention has been paid to its clinical characteristics and functional connectivity in pediatric patients with chronic TBI.Objective To evaluate the cognitive performance and spectral coherence of a group of children with TBI in non-acute phase.Method Cross-sectional study of 15 children with chronic TBI and 17 healthy children. The Neuropsychological Assessment of Children (Evaluación Neuropsicológica Infantil, ENI) was used and the resting activity of the EEG with eyes-closed was recorded. Offline, two-second epochs of the EEG of each participant were chosen and the spectral coherence was estimated in a range of 1.6 to 30 Hz. The cognitive performance between groups was compared with T-test/Mann-Whitney U Test and MANOVA for the coherence values.Results The TBI group showed a lower performance (p ≤ 0.05) in metalinguistic, visuospatial skills, attention, memory, non-verbal flexibility, planning, and organization. Differences (p ≤ 0.000) were found both inter and intrahemispherically in the spectral coherence between the groups, particularly on F1-F3 (95% CI: 0.543 - 0.557) over the whole frequency range and F3-C3 (95% CI: 0.503 - 0.515) in delta, theta, alpha2, and beta frequencies.Discussion and conclusión Our findings suggest alterations of hypo and hyper functional connectivity, particularly on the frontal and parietal lobes of both hemispheres, even after several years of a TBI. It is possible that a subtle difference in the degree of connectivity is crucial in the genesis or successful development of attentional, mnesic, executive, and visuospatial processes.Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz2019info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdf0185-3325https://www.redalyc.org/articulo.oa?id=58261085005https://www.redalyc.org/journal/582/58261085005/https://www.redalyc.org/journal/582/58261085005/html/https://www.redalyc.org/journal/582/58261085005/58261085005.epubhttps://www.redalyc.org/journal/582/58261085005/movil10.17711/SM.0185-3325.2019.012Salud Mental (México) Num.2 Vol.42reponame:Redalyc-UNAMinstname:Universidad Nacional Autónoma de Méxicoinstacron:UNAMenhttp://www.redalyc.org/revista.oa?id=582Salud Mentalinfo:eu-repo/semantics/openAccessoai:redalyc.org:582610850052025-09-03T18:07:45Z |
| dc.title.none.fl_str_mv |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| title |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| spellingShingle |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI Marlene Galicia-Alvarado Medicina EEG child cognition traumatic brain injury |
| title_short |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| title_full |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| title_fullStr |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| title_full_unstemmed |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| title_sort |
Cognitive and spectral coherence of EEG alterations in resting state in children with chronic TBI |
| dc.creator.none.fl_str_mv |
Marlene Galicia-Alvarado Javier Alducin-Castillo Maura Jazmín Ramírez-Flores Ana Laura Sánchez Quezada Oscar Yáñez-Suárez Blanca Flores-Ávalos |
| author |
Marlene Galicia-Alvarado |
| author_facet |
Marlene Galicia-Alvarado Javier Alducin-Castillo Maura Jazmín Ramírez-Flores Ana Laura Sánchez Quezada Oscar Yáñez-Suárez Blanca Flores-Ávalos |
| author_role |
author |
| author2 |
Javier Alducin-Castillo Maura Jazmín Ramírez-Flores Ana Laura Sánchez Quezada Oscar Yáñez-Suárez Blanca Flores-Ávalos |
| author2_role |
author author author author author |
| dc.subject.none.fl_str_mv |
Medicina EEG child cognition traumatic brain injury |
| topic |
Medicina EEG child cognition traumatic brain injury |
| description |
Introduction TBI is associated with alterations in cortico-subcortical connectivity. However, little attention has been paid to its clinical characteristics and functional connectivity in pediatric patients with chronic TBI.Objective To evaluate the cognitive performance and spectral coherence of a group of children with TBI in non-acute phase.Method Cross-sectional study of 15 children with chronic TBI and 17 healthy children. The Neuropsychological Assessment of Children (Evaluación Neuropsicológica Infantil, ENI) was used and the resting activity of the EEG with eyes-closed was recorded. Offline, two-second epochs of the EEG of each participant were chosen and the spectral coherence was estimated in a range of 1.6 to 30 Hz. The cognitive performance between groups was compared with T-test/Mann-Whitney U Test and MANOVA for the coherence values.Results The TBI group showed a lower performance (p ≤ 0.05) in metalinguistic, visuospatial skills, attention, memory, non-verbal flexibility, planning, and organization. Differences (p ≤ 0.000) were found both inter and intrahemispherically in the spectral coherence between the groups, particularly on F1-F3 (95% CI: 0.543 - 0.557) over the whole frequency range and F3-C3 (95% CI: 0.503 - 0.515) in delta, theta, alpha2, and beta frequencies.Discussion and conclusión Our findings suggest alterations of hypo and hyper functional connectivity, particularly on the frontal and parietal lobes of both hemispheres, even after several years of a TBI. It is possible that a subtle difference in the degree of connectivity is crucial in the genesis or successful development of attentional, mnesic, executive, and visuospatial processes. |
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2019 |
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2019 |
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info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
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article |
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publishedVersion |
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0185-3325 https://www.redalyc.org/articulo.oa?id=58261085005 https://www.redalyc.org/journal/582/58261085005/ https://www.redalyc.org/journal/582/58261085005/html/ https://www.redalyc.org/journal/582/58261085005/58261085005.epub https://www.redalyc.org/journal/582/58261085005/movil 10.17711/SM.0185-3325.2019.012 |
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0185-3325 10.17711/SM.0185-3325.2019.012 |
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https://www.redalyc.org/articulo.oa?id=58261085005 https://www.redalyc.org/journal/582/58261085005/ https://www.redalyc.org/journal/582/58261085005/html/ https://www.redalyc.org/journal/582/58261085005/58261085005.epub https://www.redalyc.org/journal/582/58261085005/movil |
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en |
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en |
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http://www.redalyc.org/revista.oa?id=582 |
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Salud Mental info:eu-repo/semantics/openAccess |
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Salud Mental |
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Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
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Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
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Salud Mental (México) Num.2 Vol.42 reponame:Redalyc-UNAM instname:Universidad Nacional Autónoma de México instacron:UNAM |
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Universidad Nacional Autónoma de México |
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