Risk factors of breast cancer in Mexican women
Objective. To investigate the association between familyhistory (FH) of neoplasia, gyneco-obstetric factors and breastcancer (BC) in a casecontrol study. In cases, to analyzethose variables in relation with early onset of BC, the mannerof detection (self-examination, prompted by pain, or casual),th...
| Authors: | , , , , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2000 |
| Country: | México |
| Institution: | Universidad Autónoma de Nuevo León |
| Repository: | Redalyc-UANL |
| OAI Identifier: | oai:redalyc.org:10642107 |
| Online Access: | https://www.redalyc.org/articulo.oa?id=10642107 |
| Access Level: | Open access |
| Keyword: | Salud Mexico risk factors Key words: breast neoplasms |
| Summary: | Objective. To investigate the association between familyhistory (FH) of neoplasia, gyneco-obstetric factors and breastcancer (BC) in a casecontrol study. In cases, to analyzethose variables in relation with early onset of BC, the mannerof detection (self-examination, prompted by pain, or casual),the size of tumor, and the elapsed time to seek medicalattention. Material and methods. Data from 151 prevalentBC cases and 235 age-matched controls were analyzed bymultiple logistic regression, to assess the influence of BCrisk factors. Results. Ten per cent of patients and 1% ofcontrols had first-degree relatives (FDR) with BC. Familyhistory of FDR with BC (OR, 11.2; 95% CI 2.42-51.92) orwith gastric or pancreatic cancer (OR, 17.7; 95% CI 2.2-142.6) was associated with BC risk. Breastfeeding at or under25 years of age was protective against BC (OR, 0.40; 95% CI0.24-0.66). The manner of tumor detection did not influenceits size at the time of diagnosis. Conclusions. Our studyconfirms that FH of BC and/or of gastric or pancreaticcarcinoma are risk factors for BC, while lactation at 25 yearsof age or earlier is protective. |
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