Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, ye...

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Autor: JHA, RAVI PRAKASH
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:México
Institución:Instituto Nacional de Salud Pública
Repositorio:Repositorio Institucional Abierto de Conocimiento en Salud Pública
Idioma:español
OAI Identifier:oai:repositorio.insp.mx:20.500.12096/8016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494974/pdf/main.pdf
https://www.doi.org/10.1016/S1474-4422(19)30034-1
http://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8016
Access Level:acceso abierto
Palabra clave:AdultAge FactorsAgedAged, 80 and overBrain Ischemia epidemiologyBrain Ischemia mortalityFemaleGlobal Burden of Disease statistics numerical data,Global HealthHumansIncidenceIntracranial Hemorrhages epidemiologyIntracranial Hemorrhages mortalityMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsStroke epidemiology,Stroke mortality,SD
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spelling Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016JHA, RAVI PRAKASHAdultAge FactorsAgedAged, 80 and overBrain Ischemia epidemiologyBrain Ischemia mortalityFemaleGlobal Burden of Disease statistics numerical data,Global HealthHumansIncidenceIntracranial Hemorrhages epidemiologyIntracranial Hemorrhages mortalityMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsStroke epidemiology,Stroke mortality,SDinfo:eu-repo/classification/cti/3Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. Methods: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, prevalence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs). DALYs were generated by summing YLLs and YLDs. Cause-specific mortality was estimated using an ensemble modelling process with vital registration and verbal autopsy data as inputs. Non-fatal estimates were generated using Bayesian meta-regression incorporating data from registries, scientific literature, administrative records, and surveys. The Socio-demographic Index (SDI), a summary indicator generated using educational attainment, lagged distributed income, and total fertility rate, was used to group countries into quintiles. Findings: In 2016, there were 5·5 million (95% UI 5·3 to 5·7) deaths and 116·4 million (111·4 to 121·4) DALYs due to stroke. The global age-standardised mortality rate decreased by 36·2% (-39·3 to -33·6) from 1990 to 2016, with decreases in all SDI quintiles. Over the same period, the global age-standardised DALY rate declined by 34·2% (-37·2 to -31·5), also with decreases in all SDI quintiles. There were 13·7 million (12·7 to 14·7) new stroke cases in 2016. Global age-standardised incidence declined by 8·1% (-10·7 to -5·5) from 1990 to 2016 and decreased in all SDI quintiles except the middle SDI group. There were 80·1 million (74·1 to 86·3) prevalent cases of stroke globally in 2016; 41·1 million (38·0 to 44·3) in women and 39·0 million (36·1 to 42·1) in men. Interpretation: Although age-standardised mortality rates have decreased sharply from 1990 to 2016, the decrease in age-standardised incidence has been less steep, indicating that the burden of stroke is likely to remain high. Planned updates to future GBD iterations include generating separate estimates for subarachnoid haemorrhage and intracerebral haemorrhage, generating estimates of transient ischaemic attack, and including atrial fibrillation as a risk factor.ESPM INSP2022-02-16T04:24:25Z2022-02-16T04:24:25Z2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionpdfsicabi.insp.mx:2019-Nonehttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494974/pdf/main.pdfhttps://www.doi.org/10.1016/S1474-4422(19)30034-1http://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8016reponame:Repositorio Institucional Abierto de Conocimiento en Salud Públicainstname:Instituto Nacional de Salud Públicainstacron:INSPspanacionalinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/4.0oai:repositorio.insp.mx:20.500.12096/80162024-08-27T22:04:31Z
dc.title.none.fl_str_mv Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
title Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
spellingShingle Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
JHA, RAVI PRAKASH
AdultAge FactorsAgedAged, 80 and overBrain Ischemia epidemiologyBrain Ischemia mortalityFemaleGlobal Burden of Disease statistics numerical data,Global HealthHumansIncidenceIntracranial Hemorrhages epidemiologyIntracranial Hemorrhages mortalityMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsStroke epidemiology,Stroke mortality,SD
info:eu-repo/classification/cti/3
title_short Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
title_full Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
title_fullStr Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
title_full_unstemmed Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
title_sort Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
dc.creator.none.fl_str_mv JHA, RAVI PRAKASH
author JHA, RAVI PRAKASH
author_facet JHA, RAVI PRAKASH
author_role author
dc.subject.none.fl_str_mv AdultAge FactorsAgedAged, 80 and overBrain Ischemia epidemiologyBrain Ischemia mortalityFemaleGlobal Burden of Disease statistics numerical data,Global HealthHumansIncidenceIntracranial Hemorrhages epidemiologyIntracranial Hemorrhages mortalityMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsStroke epidemiology,Stroke mortality,SD
info:eu-repo/classification/cti/3
topic AdultAge FactorsAgedAged, 80 and overBrain Ischemia epidemiologyBrain Ischemia mortalityFemaleGlobal Burden of Disease statistics numerical data,Global HealthHumansIncidenceIntracranial Hemorrhages epidemiologyIntracranial Hemorrhages mortalityMaleMiddle AgedPrevalenceRisk FactorsSocioeconomic FactorsStroke epidemiology,Stroke mortality,SD
info:eu-repo/classification/cti/3
description Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. Methods: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, prevalence, deaths, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs). DALYs were generated by summing YLLs and YLDs. Cause-specific mortality was estimated using an ensemble modelling process with vital registration and verbal autopsy data as inputs. Non-fatal estimates were generated using Bayesian meta-regression incorporating data from registries, scientific literature, administrative records, and surveys. The Socio-demographic Index (SDI), a summary indicator generated using educational attainment, lagged distributed income, and total fertility rate, was used to group countries into quintiles. Findings: In 2016, there were 5·5 million (95% UI 5·3 to 5·7) deaths and 116·4 million (111·4 to 121·4) DALYs due to stroke. The global age-standardised mortality rate decreased by 36·2% (-39·3 to -33·6) from 1990 to 2016, with decreases in all SDI quintiles. Over the same period, the global age-standardised DALY rate declined by 34·2% (-37·2 to -31·5), also with decreases in all SDI quintiles. There were 13·7 million (12·7 to 14·7) new stroke cases in 2016. Global age-standardised incidence declined by 8·1% (-10·7 to -5·5) from 1990 to 2016 and decreased in all SDI quintiles except the middle SDI group. There were 80·1 million (74·1 to 86·3) prevalent cases of stroke globally in 2016; 41·1 million (38·0 to 44·3) in women and 39·0 million (36·1 to 42·1) in men. Interpretation: Although age-standardised mortality rates have decreased sharply from 1990 to 2016, the decrease in age-standardised incidence has been less steep, indicating that the burden of stroke is likely to remain high. Planned updates to future GBD iterations include generating separate estimates for subarachnoid haemorrhage and intracerebral haemorrhage, generating estimates of transient ischaemic attack, and including atrial fibrillation as a risk factor.
publishDate 2019
dc.date.none.fl_str_mv 2019
2022-02-16T04:24:25Z
2022-02-16T04:24:25Z
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dc.identifier.none.fl_str_mv sicabi.insp.mx:2019-None
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494974/pdf/main.pdf
https://www.doi.org/10.1016/S1474-4422(19)30034-1
http://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8016
identifier_str_mv sicabi.insp.mx:2019-None
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494974/pdf/main.pdf
https://www.doi.org/10.1016/S1474-4422(19)30034-1
http://repositorio.insp.mx:8080/jspui/handle/20.500.12096/8016
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language spa
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