Synthesis and characterization of new 2-(alkylamino) acetamides

Seven new 2-(alkylamino) acetamides have been synthesized and characterized by 1H, 13C NMR, NOESY experiments, infrared and mass spectrometry. The structure of 2-(diphenylmethylamino) acetamide 3b was further established by a single crystal x-ray diffraction study. The NMR study of the transformatio...

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Bibliographic Details
Authors: LUIS SILVESTRE ZAMUDIO RIVERA, HIRAM ISAAC BELTRAN CONDE
Format: article
Status:Published version
Publication Date:2003
Country:México
Institution:Universidad Autónoma Metropolitana
Repository:Concentración de Recursos de Información Científica y Académica, UAM Cuajimalpa
Language:English
OAI Identifier:oai:ilitia.cua.uam.mx:123456789/57
Online Access:http://ilitia.cua.uam.mx:8080/jspui/handle/123456789/57
Access Level:Open access
Keyword:info:eu-repo/classification/cti/2
Acetamidas
Amidas
Espectroscopia
Rayos X
Description
Summary:Seven new 2-(alkylamino) acetamides have been synthesized and characterized by 1H, 13C NMR, NOESY experiments, infrared and mass spectrometry. The structure of 2-(diphenylmethylamino) acetamide 3b was further established by a single crystal x-ray diffraction study. The NMR study of the transformation of several 2-(alkylamino) acetamides to their corresponding morpholin-2-ones shows that these species are thermodynamically favored through preferred conformations as determined by theoretical calculations of 3h.