HETEROGENEITY OF VP4 NEUTRALIZATION EPITOPES AMONG SEROTYPE P1A HUMAN ROTAVIRUS STRAINS
We have used serotype-specific VP4 and VP7 neutralizing monoclonal antibodies (Nt-MAbs), as well as subgroup (SG)-specific MAbs, to characterize by enzyme immunoassay rotavirus strains isolated from diarrheic infants in the city of Monterrey, Mexico, from July 1993 to March 1994. Of a total of 465 c...
| Autores: | , , , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 1995 |
| País: | México |
| Recursos: | Universidad Nacional Autónoma de México |
| Repositório: | Sistema de Información de la Facultad de Ciencias, UNAM |
| OAI Identifier: | oai:repositorio.fciencias.unam.mx:11154/3025 |
| Acesso em linha: | http://hdl.handle.net/11154/3025 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Immunology Infectious Diseases Microbiology |
| Resumo: | We have used serotype-specific VP4 and VP7 neutralizing monoclonal antibodies (Nt-MAbs), as well as subgroup (SG)-specific MAbs, to characterize by enzyme immunoassay rotavirus strains isolated from diarrheic infants in the city of Monterrey, Mexico, from July 1993 to March 1994. Of a total of 465 children studied, 140 were rotavirus positive, including 3 patients infected with non-group A rotaviruses. The SG and VP7 (G) serotype specificities could be determined for 118 (84%) of the 140 rotavirus-positive stool specimens |
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