HETEROGENEITY OF VP4 NEUTRALIZATION EPITOPES AMONG SEROTYPE P1A HUMAN ROTAVIRUS STRAINS

We have used serotype-specific VP4 and VP7 neutralizing monoclonal antibodies (Nt-MAbs), as well as subgroup (SG)-specific MAbs, to characterize by enzyme immunoassay rotavirus strains isolated from diarrheic infants in the city of Monterrey, Mexico, from July 1993 to March 1994. Of a total of 465 c...

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Detalles Bibliográficos
Autores: CONTRERAS, JF, MENCHACA, GE, PADILLANORIEGA, L, TAMEZ, RS, GREENBERG, HB, López, S, Arias, CF
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1995
País:México
Institución:Universidad Nacional Autónoma de México
Repositorio:Sistema de Información de la Facultad de Ciencias, UNAM
OAI Identifier:oai:repositorio.fciencias.unam.mx:11154/3025
Acceso en línea:http://hdl.handle.net/11154/3025
Access Level:acceso abierto
Palabra clave:Immunology
Infectious Diseases
Microbiology
Descripción
Sumario:We have used serotype-specific VP4 and VP7 neutralizing monoclonal antibodies (Nt-MAbs), as well as subgroup (SG)-specific MAbs, to characterize by enzyme immunoassay rotavirus strains isolated from diarrheic infants in the city of Monterrey, Mexico, from July 1993 to March 1994. Of a total of 465 children studied, 140 were rotavirus positive, including 3 patients infected with non-group A rotaviruses. The SG and VP7 (G) serotype specificities could be determined for 118 (84%) of the 140 rotavirus-positive stool specimens

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