Efecto de la administración semanal de ácido fólico sobre los valores sanguíneos
Objective. To evaluate the effect of weekly administrationof 5 mg. folic acid (FA) intake on folic acid blood levels.Material and methods. This concurrent comparative studywas conducted in 1998, in urban and rural areas of NuevoLeon State, Mexico. The study population consisted of 74women who delive...
| Autores: | , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2001 |
| País: | México |
| Recursos: | Universidad Autónoma de Nuevo León |
| Repositório: | Redalyc-UANL |
| OAI Identifier: | oai:redalyc.org:10643206 |
| Acesso em linha: | https://www.redalyc.org/articulo.oa?id=10643206 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Salud Mexico neural tube defects prevention & control Key words: folic acid |
| Resumo: | Objective. To evaluate the effect of weekly administrationof 5 mg. folic acid (FA) intake on folic acid blood levels.Material and methods. This concurrent comparative studywas conducted in 1998, in urban and rural areas of NuevoLeon State, Mexico. The study population consisted of 74women who delivered a child during 1997, 39 of whom hada child with a neural tube defect. Women were given 5 mg.of folic acid, weekly for 3 months. Blood levels of folic acidwere determined by radioimmunoassay (RIA) at baseline,and a week after taking the last folic acid dose. Data arepresented as means and standard deviations. Results.Ninety per cent of the women had significantly increasedfolic acid intraerythrocytary blood levels. Red cell folateincreased from 150.49 ± 31.17 ng/ml to 184.21 ± 35.53ng/ml (p<0.005). Plasma folate increased from 5.93 ± 1.98ng/ml a 7.03 ± 2.5 ng/ml (p<0.05). Eighty-two per cent ofwomen reached intracellular levels above 160 ng/ml.Conclusions. The weekly administration of folic acid is asimple and efficient method that could be used tosupplement this vitamin to low-income populations.TheEnglish version of this paper is available at: http://www.insp.mx/salud/index.html |
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