Antibacterial Activity of Pipemidic Acid ions-MgFeAl Layered Double Hydroxide Hybrid Against E. coli and S. typhi

An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacteri...

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Detalles Bibliográficos
Autores: Alejandra Santana-Cruz, Jorge Luis Flores-Moreno, Roberto Guerra-González, María de Jesús Martínez-Ortiz
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:México
Institución:Universidad Michoacana de San Nicolás de Hidalgo
Repositorio:Redalyc-UMSNH
OAI Identifier:oai:redalyc.org:47546935003
Acceso en línea:https://www.redalyc.org/articulo.oa?id=47546935003
Access Level:acceso abierto
Palabra clave:Química
intercalation
pipemidic acid
hybrid material
antibacterial activity
Layered double hydroxide
Descripción
Sumario:An anion exchange process was used to prepare pipemidic acid-MgFeAl composite from MgFeAl-Cl layered double hydroxide as inorganic matrix. The obtained hybrid material contains pipemidic acid anions as well as, in a less extent; carbonate and chloride species in its interlayer space. The antibacterial properties were evaluated against E. coli and S. typhi strains through dilution broth method. MgFeAl-Cl matrix resulted to be completely inactive against two bacteria, while MgFeAl-PIP composite killed all colonies of E. coli after 90 min of exposure and showed a good activity to kill S. typhi bacteria at times as short as 120 min.