Infrared Irradiation-Assisted Multicomponent Synthesis of 2-Amino-3- cyano-4H-pyran Derivatives

A simple, versatile, and efficient synthesis of 4H-pyran derivative compounds is achieved via a three-component cyclocondensation of aldehydes, malononitrile, and ethyl acetoacetate, usingammonium hydroxide as the catalyst, promoted by infrared irradiation. The present method offers several advantag...

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Detalles Bibliográficos
Autores: Arturo Sánchez, Fernando Hernández, Paulo César Cruz, Yolanda Alcaraz, Joaquín Tamariz, Francisco Delgado, Miguel A. Vázquez
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:México
Institución:Universidad de Guanajuato
Repositorio:Redalyc-UG
OAI Identifier:oai:redalyc.org:47523306006
Acceso en línea:https://www.redalyc.org/articulo.oa?id=47523306006
Access Level:acceso abierto
Palabra clave:Química
4H
MCR
Three
pyrans
component reaction
Descripción
Sumario:A simple, versatile, and efficient synthesis of 4H-pyran derivative compounds is achieved via a three-component cyclocondensation of aldehydes, malononitrile, and ethyl acetoacetate, usingammonium hydroxide as the catalyst, promoted by infrared irradiation. The present method offers several advantages, such as high yields, nonhazardous reaction conditions as well as short reaction times.