Pleural mesothelioma in paraoccupational, environmental and occupational patients exposed to asbestos

Objective: to identify the characteristics of pleural mesothelioma in patients exposed to asbestos. Methods: a transversal study in 3700 cases of lung cancer was conducted. There were identified 21 cases with mesothelioma. Age, gender, smoking history, cancer development, dissemination, cyto- histoc...

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Detalles Bibliográficos
Autores: María Martha Méndez-Vargas, Pablo López-Rojas, Guillermo Armando Campos-Pujal, Irma Araceli Marín-Cotoñieto, Santiago Salinas-Tovar, María de Jesús Fernández-Muñoz
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:México
Institución:Universidad Nacional Autónoma de México
Repositorio:Redalyc-UNAM
OAI Identifier:oai:redalyc.org:457745509004
Acceso en línea:https://www.redalyc.org/articulo.oa?id=457745509004
Access Level:acceso abierto
Palabra clave:Medicina
diseases
asbestos
Mesothelioma pleural
occupational diseases
Descripción
Sumario:Objective: to identify the characteristics of pleural mesothelioma in patients exposed to asbestos. Methods: a transversal study in 3700 cases of lung cancer was conducted. There were identified 21 cases with mesothelioma. Age, gender, smoking history, cancer development, dissemination, cyto- histochemistry, lethality and total lung capacity were studied. ANOVA test was used. Results: the incidence was of 0.45/100,000 patients. Four (19 %) corresponded to occupational exposure (OE), seven (33 %) para-occupational (PE) and ten (48 %) environmental (EE). The mean age at de- tection was 50 years for PE, 55 years for EE and 64 years for OE. Twenty cases were male. Thirteen patients (62 %) were active cigarette smokers. The latency time in PE mesothelioma was 34.5 years, in OE 40 years, and in EE more than 40 years. In 19 (90 %) cases the tumor was disseminated. Diagno- sis was confirmed by cytohistochemistry. Malignant mesothelioma was reported in 19 (90 %) cases. The survival period was 5 months for OE patients, 10 in PE and 16 in EE. Conclusions: there is a low incidence of malignant mesothelioma in our population. Male was the pre- dominant group. Occupational and paraoccupational exposure predominated in patients.