Comparison of butyrylcholinesterase activity between inhabitants of a rural and an urban area of Guerrero, Mexico

Human exposure to cholinesterase inhibitor pesticides can vary according to the type and frequency of products used, protective measures, and organisms to be controlled at a given site. Vector-borne disease control programs are carried out mainly in urban areas, while agricultural pest control is ca...

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Detalles Bibliográficos
Autores: Martínez-Rosas, Maroli Getsemani, Chávez-Almazán, Luis Alberto, Garibo-Ruiz, Diana, Sánchez-Visoso, Fany Itzel, Calleja-Villalva, Eridia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:México
Institución:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO
Repositorio:Revista Internacional de Contaminación Ambiental
Idioma:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/54555
Acceso en línea:https://www.revistascca.unam.mx/rica/index.php/rica/article/view/54555
Access Level:acceso abierto
Palabra clave:butirilcolinesterasa
intoxicación
plaguicidas organofosforados
carbamatos
butyrylcholinesterase
poisoning
organophosphate pesticides
carbamates
Descripción
Sumario:Human exposure to cholinesterase inhibitor pesticides can vary according to the type and frequency of products used, protective measures, and organisms to be controlled at a given site. Vector-borne disease control programs are carried out mainly in urban areas, while agricultural pest control is carried out in rural areas, so exposure may be different between the people who live in one place or another. This study aimed to determine the difference in serum butyrylcholinesterase activity from a rural and an urban population. Voluntarily, 120 individuals over 18 years of age participated in the study, of which 70 (36 women and 34 men) are inhabitants of Chilpancingo de Los Bravo, and 50 (23 women and 27 men) from the town of Tilapa (Guerrero, Mexico). Through a blood sample, butyrylcholinesterase was analyzed in the participants and then compared according to locality of origin, sex, age, education, and occupation. Butyrylcholinesterase activity was decreased in Tilapa with respect to Chilpancingo (5041 vs. 5448 U/L, respectively; p = 0.291). There was no significant difference in the activity of this enzyme between both populations, however, it is essential to strengthen the research on human exposure to cholinesterase inhibitor pesticides in urban and rural areas to identify potential risks that should be addressed by health authorities and agriculture.