Lipid bilayer-coated nanoparticles: mimetism for biomedical applications
Living organisms are made of self-assembled nanostructures. Therefore, the control of sizes, shapes, textures, or chemical functions during chemical synthesis, as managed by nanotechnology, leads to a myriad of possibilities in the field of biomedical applications. One of the main approaches in this...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2023 |
| País: | México |
| Institución: | UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO |
| Repositorio: | Mundo Nano. Revista Interdisciplinaria en Nanociencias y Nanotecnología |
| Idioma: | inglés español |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/69797 |
| Acceso en línea: | https://www.mundonano.unam.mx/ojs/index.php/nano/article/view/69797 |
| Access Level: | acceso abierto |
| Palabra clave: | supported lipid bilayers biomimetism membrane patches hybrid nanoparticles liposomes |
| Sumario: | Living organisms are made of self-assembled nanostructures. Therefore, the control of sizes, shapes, textures, or chemical functions during chemical synthesis, as managed by nanotechnology, leads to a myriad of possibilities in the field of biomedical applications. One of the main approaches in this area, also known as nanomedicine, is the production of biomimetic nanoparticles, which take profit from either natural products or bioinspired materials. Cell-cell communications are strongly dependent on molecular arrays displayed at the cell surface in the context of lipid bilayers. Therefore, the mimicry of such coatings has gained great interest during the last decades. Herein we summarize the rationale and the methodologies related to this approach, with a special focus on the delivery of drugs and vaccines. The challenges and opportunities in this area, along with some selected examples will be discussed as well. |
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