INDUCTION OF MICRONUCLEI IN PERIPHERAL ERYTHROCYTES OF CYPRINUS CARPIO FISH BY METHYL PARATHION

Methyl parathion (MP) is a commonly used organophosphorus insecticide, commercially available as Folidol 600. This chemical substance was tested to determine micronucleus (MN) frequencies in peripheral erythrocytes of the fish Cypnnus ceio treated in vivo.The concentrations tested were 1.25,2.50,5.0...

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Detalles Bibliográficos
Autores: NEPOMUCENO, Júlio César, SPANÓ, Mário Antonio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:México
Institución:UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO
Repositorio:Revista Internacional de Contaminación Ambiental
Idioma:español
OAI Identifier:oai:ojs.pkp.sfu.ca:article/30538
Acceso en línea:https://www.revistascca.unam.mx/rica/index.php/rica/article/view/30538
Access Level:acceso abierto
Palabra clave:Cypinus cap
micronucleus test
methyl parathion
Descripción
Sumario:Methyl parathion (MP) is a commonly used organophosphorus insecticide, commercially available as Folidol 600. This chemical substance was tested to determine micronucleus (MN) frequencies in peripheral erythrocytes of the fish Cypnnus ceio treated in vivo.The concentrations tested were 1.25,2.50,5.00 and 7.50 ppm. Fish were killed after 24 or 48 h of treatment. There was a significant increase in the frequency of micronuclei in the animals treated with 2.50 and 5.00 ppm after 24 h. At higher dosages this effect disap peared probably due to the increased cell lethality. The frequency of MN induction was lower at 48 than at 24 h after treatment. There was a dosedependent increase in MN frequency which, however, was significant only at the highest concentration (7.50 ppm) compared to control.