Metronidazole induced encephalopathy

Metronidazole, a commonly used antibiotic, is a drug of the family of 5-nitroimidazoles, which has antiparasitic and antibacterial properties in anaerobic organisms. A number of side effects to its use has been described, rare adverse effects also has been reported, included Metronidazole Induced En...

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Detalles Bibliográficos
Autores: López-Contreras, Luilli, Calva-Espitia , Dulce S., Hernández-Ceruelos, Alejandra
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:México
Institución:UNIVERSIDAD AUTÓNOMA DEL ESTADO DE HIDALGO
Repositorio:Educación y salud Boletín Científico Instituto de Ciencias de la Salud Universidad Autónoma del Estado de Hidalgo
Idioma:español
OAI Identifier:oai:repository.uaeh.edu.mx:article/6520
Acceso en línea:https://repository.uaeh.edu.mx/revistas/index.php/ICSA/article/view/6520
Access Level:acceso abierto
Palabra clave:Metronidazole
Metronidazole Induced Encephalo
metronidazol
encefalopatía inducida por metronidazol
toxicidad
Descripción
Sumario:Metronidazole, a commonly used antibiotic, is a drug of the family of 5-nitroimidazoles, which has antiparasitic and antibacterial properties in anaerobic organisms. A number of side effects to its use has been described, rare adverse effects also has been reported, included Metronidazole Induced Encephalopathy (MIE). MIE is potentially reversible neurological disorder. It is characterized by central and peripheral neurological disorders such as dysarthria, disturbances in consciousness, ataxic gait, paraesthesia, polyneuropathy, and less frequently seizures occur. The diagnosis is based on the clinic, identifying the history of consumption of Metronidazole and evidencing hyperdense images at the level of the dentate ganglia on a nuclear magnetic resonance imaging of the skull, with reversal of the picture after suspending the consumption of Metronidazole. It is important not only to identify the clinical picture to suspend the consumption of this drug, also, it is necessary inform to patients about the possible adverse effects of Metronidazole use, included MIE.