Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment

Anther extrusion (AE) is the most important male floral trait for hybrid wheat seed production. AE is a complex quantitative trait that is difficult to phenotype reliably in field experiments not only due to high genotype-by-environment effects but also due to the short expression window in the fiel...

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Autores: Adhikari, A., Basnet, B.R., Crossa, J., Dreisigacker, S., Camarillo-Castillo, F., Bhati, P., Jarquin, D., Yann Manes, Ibrahim, A.M.H.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:México
Institución:Centro Internacional de Mejoramiento de Maíz y Trigo
Repositorio:Repositorio Institucional de Publicaciones Multimedia del CIMMYT
OAI Identifier:oai:repository.cimmyt.org:10883/21082
Acceso en línea:https://hdl.handle.net/10883/21082
Access Level:acceso abierto
Palabra clave:AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
GWAS
Anther Extrusion
Floral Traits
Hybrid Wheat
Genome-Wide Prediction
ANTHERS
WHEAT
HYBRIDS
GENOMES
BREEDING
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spelling Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environmentAdhikari, A.Basnet, B.R.Crossa, J.Dreisigacker, S.Camarillo-Castillo, F.Bhati, P.Jarquin, D.Yann ManesIbrahim, A.M.H.AGRICULTURAL SCIENCES AND BIOTECHNOLOGYGWASAnther ExtrusionFloral TraitsHybrid WheatGenome-Wide PredictionANTHERSWHEATHYBRIDSGENOMESBREEDINGAnther extrusion (AE) is the most important male floral trait for hybrid wheat seed production. AE is a complex quantitative trait that is difficult to phenotype reliably in field experiments not only due to high genotype-by-environment effects but also due to the short expression window in the field condition. In this study, we conducted a genome-wide association scan (GWAS) and explored the possibility of applying genomic prediction (GP) for AE in the CIMMYT hybrid wheat breeding program. An elite set of male lines (n = 603) were phenotype for anther count (AC) and anther visual score (VS) across three field experiments in 2017–2019 and genotyped with the 20K Infinitum is elect SNP array. GWAS produced five marker trait associations with small effects. For GP, the main effects of lines (L), environment (E), genomic (G) and pedigree relationships (A), and their interaction effects with environments were used to develop seven statistical models of incremental complexity. The base model used only L and E, whereas the most complex model included L, E, G, A, and G × E and A × E. These models were evaluated in three cross-validation scenarios (CV0, CV1, and CV2). In cross-validation CV0, data from two environments were used to predict an untested environment; in random cross-validation CV1, the test set was never evaluated in any environment; and in CV2, the genotypes in the test set were evaluated in only a subset of environments. The prediction accuracies ranged from −0.03 to 0.74 for AC and −0.01 to 0.54 for VS across different models and CV schemes. For both traits, the highest prediction accuracies with low variance were observed in CV2, and inclusion of the interaction effects increased prediction accuracy for AC only. In CV0, the prediction accuracy was 0.73 and 0.45 for AC and VS, respectively, indicating the high reliability of across environment prediction. Genomic prediction appears to be a very reliable tool for AE in hybrid wheat breeding. Moreover, high prediction accuracy in CV0 demonstrates the possibility of implementing genomic selection across breeding cycles in related germplasm, aiding the rapid breeding cycle.Frontiers Media2020-12-19T01:20:14Z2020-12-19T01:20:14Z2020Published Versioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10883/2108210.3389/fgene.2020.586687111664-8021Frontiers in Genetics586687reponame:Repositorio Institucional de Publicaciones Multimedia del CIMMYTinstname:Centro Internacional de Mejoramiento de Maíz y Trigoinstacron:CIMMYTEnglishhttp://hdl.handle.net/11529/10548495https://figshare.com/collections/Genome-Wide_Association_Mapping_and_Genomic_Prediction_of_Anther_Extrusion_in_CIMMYT_Hybrid_Wheat_Breeding_Program_via_Modeling_Pedigree_Genomic_Relationship_and_Interaction_With_the_Environment/5233379SwitzerlandCIMMYT manages Intellectual Assets as International Public Goods. The user is free to download, print, store and share this work. In case you want to translate or create any other derivative work and share or distribute such translation/derivative work, please contact CIMMYT-Knowledge-Center@cgiar.org indicating the work you want to use and the kind of use you intend; CIMMYT will contact you with the suitable license for that purposeOpen Accessinfo:eu-repo/semantics/openAccessoai:repository.cimmyt.org:10883/210822024-10-11T19:59:12Z
dc.title.none.fl_str_mv Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
title Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
spellingShingle Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
Adhikari, A.
AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
GWAS
Anther Extrusion
Floral Traits
Hybrid Wheat
Genome-Wide Prediction
ANTHERS
WHEAT
HYBRIDS
GENOMES
BREEDING
title_short Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
title_full Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
title_fullStr Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
title_full_unstemmed Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
title_sort Genome-wide association mapping and genomic prediction of anther extrusion in CIMMYT hybrid wheat breeding program via modeling pedigree, genomic relationship, and interaction with the environment
dc.creator.none.fl_str_mv Adhikari, A.
Basnet, B.R.
Crossa, J.
Dreisigacker, S.
Camarillo-Castillo, F.
Bhati, P.
Jarquin, D.
Yann Manes
Ibrahim, A.M.H.
author Adhikari, A.
author_facet Adhikari, A.
Basnet, B.R.
Crossa, J.
Dreisigacker, S.
Camarillo-Castillo, F.
Bhati, P.
Jarquin, D.
Yann Manes
Ibrahim, A.M.H.
author_role author
author2 Basnet, B.R.
Crossa, J.
Dreisigacker, S.
Camarillo-Castillo, F.
Bhati, P.
Jarquin, D.
Yann Manes
Ibrahim, A.M.H.
author2_role author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
GWAS
Anther Extrusion
Floral Traits
Hybrid Wheat
Genome-Wide Prediction
ANTHERS
WHEAT
HYBRIDS
GENOMES
BREEDING
topic AGRICULTURAL SCIENCES AND BIOTECHNOLOGY
GWAS
Anther Extrusion
Floral Traits
Hybrid Wheat
Genome-Wide Prediction
ANTHERS
WHEAT
HYBRIDS
GENOMES
BREEDING
description Anther extrusion (AE) is the most important male floral trait for hybrid wheat seed production. AE is a complex quantitative trait that is difficult to phenotype reliably in field experiments not only due to high genotype-by-environment effects but also due to the short expression window in the field condition. In this study, we conducted a genome-wide association scan (GWAS) and explored the possibility of applying genomic prediction (GP) for AE in the CIMMYT hybrid wheat breeding program. An elite set of male lines (n = 603) were phenotype for anther count (AC) and anther visual score (VS) across three field experiments in 2017–2019 and genotyped with the 20K Infinitum is elect SNP array. GWAS produced five marker trait associations with small effects. For GP, the main effects of lines (L), environment (E), genomic (G) and pedigree relationships (A), and their interaction effects with environments were used to develop seven statistical models of incremental complexity. The base model used only L and E, whereas the most complex model included L, E, G, A, and G × E and A × E. These models were evaluated in three cross-validation scenarios (CV0, CV1, and CV2). In cross-validation CV0, data from two environments were used to predict an untested environment; in random cross-validation CV1, the test set was never evaluated in any environment; and in CV2, the genotypes in the test set were evaluated in only a subset of environments. The prediction accuracies ranged from −0.03 to 0.74 for AC and −0.01 to 0.54 for VS across different models and CV schemes. For both traits, the highest prediction accuracies with low variance were observed in CV2, and inclusion of the interaction effects increased prediction accuracy for AC only. In CV0, the prediction accuracy was 0.73 and 0.45 for AC and VS, respectively, indicating the high reliability of across environment prediction. Genomic prediction appears to be a very reliable tool for AE in hybrid wheat breeding. Moreover, high prediction accuracy in CV0 demonstrates the possibility of implementing genomic selection across breeding cycles in related germplasm, aiding the rapid breeding cycle.
publishDate 2020
dc.date.none.fl_str_mv 2020-12-19T01:20:14Z
2020-12-19T01:20:14Z
2020
dc.type.none.fl_str_mv Published Version
info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/10883/21082
10.3389/fgene.2020.586687
url https://hdl.handle.net/10883/21082
identifier_str_mv 10.3389/fgene.2020.586687
dc.language.none.fl_str_mv English
language_invalid_str_mv English
dc.relation.none.fl_str_mv http://hdl.handle.net/11529/10548495
https://figshare.com/collections/Genome-Wide_Association_Mapping_and_Genomic_Prediction_of_Anther_Extrusion_in_CIMMYT_Hybrid_Wheat_Breeding_Program_via_Modeling_Pedigree_Genomic_Relationship_and_Interaction_With_the_Environment/5233379
dc.rights.none.fl_str_mv Open Access
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Open Access
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv Switzerland
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv 11
1664-8021
Frontiers in Genetics
586687
reponame:Repositorio Institucional de Publicaciones Multimedia del CIMMYT
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instacron:CIMMYT
instname_str Centro Internacional de Mejoramiento de Maíz y Trigo
instacron_str CIMMYT
institution CIMMYT
reponame_str Repositorio Institucional de Publicaciones Multimedia del CIMMYT
collection Repositorio Institucional de Publicaciones Multimedia del CIMMYT
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