Constituents from Tithonia diversifolia. Stereochemical Revision of 2&-Hydroxytirotundin
A chemical study of the aerial parts of Tithonia diversifolialed to the isolation and stereostructural characterization of tagitininsA (1), C (2) and F (3), and a mixture of sterols. Tagitinin A (1) underwentspontaneous dehydration to 4 during the course of its 1H NMRmeasurement in CDCl3. The stereo...
| Autores: | , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2006 |
| País: | México |
| Institución: | Universidad Nacional Autónoma de México |
| Repositorio: | Redalyc-UNAM |
| OAI Identifier: | oai:redalyc.org:47550407 |
| Acceso en línea: | https://www.redalyc.org/articulo.oa?id=47550407 |
| Access Level: | acceso abierto |
| Palabra clave: | Química 2α Tagitinins furanheliangolides Tithonia diversifolia sesquiterpene lactones |
| Sumario: | A chemical study of the aerial parts of Tithonia diversifolialed to the isolation and stereostructural characterization of tagitininsA (1), C (2) and F (3), and a mixture of sterols. Tagitinin A (1) underwentspontaneous dehydration to 4 during the course of its 1H NMRmeasurement in CDCl3. The stereochemical analysis of 2α-hydroxytirotundin(5), an isomer of 1 previously reported by Kinghorn et al,led to the correction of its 3S,10S configuration to the 3S,10R stereochemistry.In addition, bioactivity evaluation of isolates showed themto exhibit moderate anti-inflammatory and cytotoxic activity |
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