GENOTOXICITY OF COMMERCIAL PETROL SAMPLES IN CULTURED HUMAN LYMPHOCYTES
Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures...
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2012 |
| País: | México |
| Recursos: | UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO |
| Repositorio: | Revista Internacional de Contaminación Ambiental |
| Idioma: | español |
| OAI Identifier: | oai:ojs.pkp.sfu.ca:article/31355 |
| Acesso em linha: | https://www.revistascca.unam.mx/rica/index.php/rica/article/view/31355 |
| Access Level: | acceso abierto |
| Palavra-chave: | petrol human lymphocyte cultures micronuclei sister-chromatid exchanges |
| Resumo: | Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 µl/ml). From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency. |
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