Avaluació de la funció renal en la millora de la predicció del risc vascular. Anàlisi del rol de les estatines en la prevenció primària d’esdeveniments cardiovasculars en la població amb malaltia renal crònica inicial
Cardiovascular diseases are the leading cause of mortality and morbidity worldwide as well as in our population. One of the main cardiovascular prevention strategies is to identify healthy patients who are at risk of cardiovascular disease and prescribe preventive measures. Cardiovascular risk funct...
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| Tipo de recurso: | tesis doctoral |
| Estado: | Versión publicada |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | CBUC, CESCA |
| Repositorio: | TDR. Tesis Doctorales en Red |
| OAI Identifier: | oai:www.tdx.cat:10803/670292 |
| Acceso en línea: | http://hdl.handle.net/10803/670292 |
| Access Level: | acceso abierto |
| Palabra clave: | Malalties cardiovasculars Enfermedades cardiovasculares Cardiovascular diseases Prevenció Prevención Prevention Risc Riesgo Risk Malaltia renal crònica Enfermedad renal crónica Chronic kidney disease Estatines Estatinas Statins 616.1 616.6 |
| Sumario: | Cardiovascular diseases are the leading cause of mortality and morbidity worldwide as well as in our population. One of the main cardiovascular prevention strategies is to identify healthy patients who are at risk of cardiovascular disease and prescribe preventive measures. Cardiovascular risk functions help us to identify these patients, but they still do not perform well enough, especially at identifying patients at intermediate risk. Chronic kidney disease (CKD) is associated with cardiovascular disease. Therefore, markers of renal function such as glomerular filtration rate (GFR) could be a useful cardiovascular risk marker to improve cardiovascular risk functions. Our study shows that in the general population without previous cardiovascular disease and low incidence of coronary heart disease, decreased GFR is associated with a clinically significant increased risk of cardiovascular events and all cause mortality from the earliest CKD stages: CKD category G3a. However, GFR doesn’t improve the performance of cardiovascular risk functions |
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