Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans

Numerous studies of human populations in Europe and Asia have revealed a concordance between their extant genetic structure and the prevailing regional pattern of geography and language. For native South Americans, however, such evidence has been lacking so far. Therefore, we examined the relationsh...

Descripción completa

Detalles Bibliográficos
Autores: Roewer, Lutz, Nothnagel, Michael, Gusmão, Leonor, Gomes, Veronica, González, Miguel, Corach, Daniel, Sala, Andrea, Alechine, Evguenia, Palha, Teresinha, Santos, Ney, Ribeiro-dos-Santos, Andrea, Geppert, Maria, Willuweit, Sascha, Nagy, Marion, Zweynert, Sarah, Baeta, Miriam, Núñez, Carolina, Martínez-Jarreta, Begoña, González-Andrade, Fabricio, Turbón, Daniel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/36040
Acceso en línea:https://hdl.handle.net/2445/36040
Access Level:acceso abierto
Palabra clave:Genètica
Genètica de poblacions humanes
Genètica evolutiva
Pobles indígenes de l'Amèrica del Sud
Genetics
Human population genetics
Evolutionary genetics
Indigenous peoples of South America
id ES_ffceeff633cc4fa313b9adba7935d596
oai_identifier_str oai:recercat.cat:2445/36040
network_acronym_str ES
network_name_str España
repository_id_str
spelling Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South AmericansRoewer, LutzNothnagel, MichaelGusmão, LeonorGomes, VeronicaGonzález, MiguelCorach, DanielSala, AndreaAlechine, EvgueniaPalha, TeresinhaSantos, NeyRibeiro-dos-Santos, AndreaGeppert, MariaWilluweit, SaschaNagy, MarionZweynert, SarahBaeta, MiriamNúñez, CarolinaMartínez-Jarreta, BegoñaGonzález-Andrade, FabricioTurbón, DanielGenèticaGenètica de poblacions humanesGenètica evolutivaPobles indígenes de l'Amèrica del SudGeneticsHuman population geneticsEvolutionary geneticsIndigenous peoples of South AmericaNumerous studies of human populations in Europe and Asia have revealed a concordance between their extant genetic structure and the prevailing regional pattern of geography and language. For native South Americans, however, such evidence has been lacking so far. Therefore, we examined the relationship between Y-chromosomal genotype on the one hand, and male geographic origin and linguistic affiliation on the other, in the largest study of South American natives to date in terms of sampled individuals and populations. A total of 1,011 individuals, representing 50 tribal populations from 81 settlements, were genotyped for up to 17 short tandem repeat (STR) markers and 16 single nucleotide polymorphisms (Y-SNPs), the latter resolving phylogenetic lineages Q and C. Virtually no structure became apparent for the extant Y-chromosomal genetic variation of South American males that could sensibly be related to their inter-tribal geographic and linguistic relationships. This continent-wide decoupling is consistent with a rapid peopling of the continent followed by long periods of isolation in small groups. Furthermore, for the first time, we identified a distinct geographical cluster of Y-SNP lineages C-M217 (C3*) in South America. Such haplotypes are virtually absent from North and Central America, but occur at high frequency in Asia. Together with the locally confined Y-STR autocorrelation observed in our study as a whole, the available data therefore suggest a late introduction of C3* into South America no more than 6,000 years ago, perhaps via coastal or trans-Pacific routes. Extensive simulations revealed that the observed lack of haplogroup C3* among extant North and Central American natives is only compatible with low levels of migration between the ancestor populations of C3* carriers and non-carriers. In summary, our data highlight the fact that a pronounced correlation between genetic and geographic/cultural structure can only be expected under very specific conditions, most of which are likely not to have been met by the ancestors of native South Americans.Public Library of Science (PLoS)2013201320132013info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion16 p.application/pdfhttps://hdl.handle.net/2445/36040Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: http://dx.doi.org/10.1371/journal.pgen.1003460PLoS Genetics, 2013, vol. 9, num. 4, p. e1003460http://dx.doi.org/10.1371/journal.pgen.1003460cc-by (c) Roewer, L. et al., 2013http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:recercat.cat:2445/360402026-05-29T05:05:01Z
dc.title.none.fl_str_mv Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
title Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
spellingShingle Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
Roewer, Lutz
Genètica
Genètica de poblacions humanes
Genètica evolutiva
Pobles indígenes de l'Amèrica del Sud
Genetics
Human population genetics
Evolutionary genetics
Indigenous peoples of South America
title_short Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
title_full Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
title_fullStr Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
title_full_unstemmed Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
title_sort Continent-wide decoupling of Y-chromosomal genetic variation from language and geography in native South Americans
dc.creator.none.fl_str_mv Roewer, Lutz
Nothnagel, Michael
Gusmão, Leonor
Gomes, Veronica
González, Miguel
Corach, Daniel
Sala, Andrea
Alechine, Evguenia
Palha, Teresinha
Santos, Ney
Ribeiro-dos-Santos, Andrea
Geppert, Maria
Willuweit, Sascha
Nagy, Marion
Zweynert, Sarah
Baeta, Miriam
Núñez, Carolina
Martínez-Jarreta, Begoña
González-Andrade, Fabricio
Turbón, Daniel
author Roewer, Lutz
author_facet Roewer, Lutz
Nothnagel, Michael
Gusmão, Leonor
Gomes, Veronica
González, Miguel
Corach, Daniel
Sala, Andrea
Alechine, Evguenia
Palha, Teresinha
Santos, Ney
Ribeiro-dos-Santos, Andrea
Geppert, Maria
Willuweit, Sascha
Nagy, Marion
Zweynert, Sarah
Baeta, Miriam
Núñez, Carolina
Martínez-Jarreta, Begoña
González-Andrade, Fabricio
Turbón, Daniel
author_role author
author2 Nothnagel, Michael
Gusmão, Leonor
Gomes, Veronica
González, Miguel
Corach, Daniel
Sala, Andrea
Alechine, Evguenia
Palha, Teresinha
Santos, Ney
Ribeiro-dos-Santos, Andrea
Geppert, Maria
Willuweit, Sascha
Nagy, Marion
Zweynert, Sarah
Baeta, Miriam
Núñez, Carolina
Martínez-Jarreta, Begoña
González-Andrade, Fabricio
Turbón, Daniel
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Genètica
Genètica de poblacions humanes
Genètica evolutiva
Pobles indígenes de l'Amèrica del Sud
Genetics
Human population genetics
Evolutionary genetics
Indigenous peoples of South America
topic Genètica
Genètica de poblacions humanes
Genètica evolutiva
Pobles indígenes de l'Amèrica del Sud
Genetics
Human population genetics
Evolutionary genetics
Indigenous peoples of South America
description Numerous studies of human populations in Europe and Asia have revealed a concordance between their extant genetic structure and the prevailing regional pattern of geography and language. For native South Americans, however, such evidence has been lacking so far. Therefore, we examined the relationship between Y-chromosomal genotype on the one hand, and male geographic origin and linguistic affiliation on the other, in the largest study of South American natives to date in terms of sampled individuals and populations. A total of 1,011 individuals, representing 50 tribal populations from 81 settlements, were genotyped for up to 17 short tandem repeat (STR) markers and 16 single nucleotide polymorphisms (Y-SNPs), the latter resolving phylogenetic lineages Q and C. Virtually no structure became apparent for the extant Y-chromosomal genetic variation of South American males that could sensibly be related to their inter-tribal geographic and linguistic relationships. This continent-wide decoupling is consistent with a rapid peopling of the continent followed by long periods of isolation in small groups. Furthermore, for the first time, we identified a distinct geographical cluster of Y-SNP lineages C-M217 (C3*) in South America. Such haplotypes are virtually absent from North and Central America, but occur at high frequency in Asia. Together with the locally confined Y-STR autocorrelation observed in our study as a whole, the available data therefore suggest a late introduction of C3* into South America no more than 6,000 years ago, perhaps via coastal or trans-Pacific routes. Extensive simulations revealed that the observed lack of haplogroup C3* among extant North and Central American natives is only compatible with low levels of migration between the ancestor populations of C3* carriers and non-carriers. In summary, our data highlight the fact that a pronounced correlation between genetic and geographic/cultural structure can only be expected under very specific conditions, most of which are likely not to have been met by the ancestors of native South Americans.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013
2013
2013
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/36040
url https://hdl.handle.net/2445/36040
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1371/journal.pgen.1003460
PLoS Genetics, 2013, vol. 9, num. 4, p. e1003460
http://dx.doi.org/10.1371/journal.pgen.1003460
dc.rights.none.fl_str_mv cc-by (c) Roewer, L. et al., 2013
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Roewer, L. et al., 2013
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 16 p.
application/pdf
dc.publisher.none.fl_str_mv Public Library of Science (PLoS)
publisher.none.fl_str_mv Public Library of Science (PLoS)
dc.source.none.fl_str_mv Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869425807830548480
score 15.812455

Similares en LA Referencia