All peptides induce identical conformation in Rap3T

(a) RMSD calculation from the superimposition of Cα atoms of Rap3T structures in complex with peptides SRGHTS, RGHTS, RRGHTA, and RRGHTAS. RMSD were calculated from individual monomers (lower) and dimers (upper). Number of atoms used in RMSD calculation is showed between parenthesis. (b) Superpositi...

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Detalles Bibliográficos
Autores: Felipe-Ruiz, Alonso, Zamora-Caballero, Sara, Bendori, Shira Omer, Penadés, José R., Eldar, Avigdor, Marina, Alberto
Tipo de recurso: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/372064
Acceso en línea:http://hdl.handle.net/10261/372064
Access Level:acceso abierto
Palabra clave:Small signaling molecules
Produce identical structural
Opening new possibilities
Exhibit different types
Microbial social behaviors
Bacillus subtilis
Prevalent qs systems
Systems playing
Coordinating behaviors
Bacillota
Varying affinities
Several cases
Secreted oligopeptides
RRNPPA family
Results reveal
Receptor specificity
Quorum sensing
qs communication
Produced pheromones
Processes governing
Pheromone duplication
Mediating communication
Intricate nature
Functional significance
Functional activities
Extracellular proteolysis
Extracellular proteases
Diversify peptide
Changing environments
Central role
Biological responses
Bacteriophages infecting
Bacterial interactions
Active pheromones
Quorum Sensing
https://www.ncbi.nlm.nih.gov/mesh/68053038
https://www.ncbi.nlm.nih.gov/mesh/68001412
Descripción
Sumario:(a) RMSD calculation from the superimposition of Cα atoms of Rap3T structures in complex with peptides SRGHTS, RGHTS, RRGHTA, and RRGHTAS. RMSD were calculated from individual monomers (lower) and dimers (upper). Number of atoms used in RMSD calculation is showed between parenthesis. (b) Superposition of 4 Rap3T-Peptide complexes with different pheromone variants in monomeric state RRGHTAS (blue), RRGHTA (pink), RGHTS (light green), and SRGHTS (orange). (c) Superposition of dimers for the 4 Rap3T complexes with peptides RRGHTAS (blue), RRGHTA (pink), RGHTS (light green), and SRGHTS (orange).