Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

Murcia-Lesmes, David; Domínguez López, Inés; Laveriano-Santos, Emily P.; Tresserra i Rimbau, Anna; Castro-Barquero, Sara; Estruch Riba, Ramon; Vázquez Ruiz, Zenaida; Ruiz Canela, Miguel; Razquin, Cristina; Corella Piquer, Dolores; Sorlí, José V.; Salas Salvadó, Jordi; Pérez Vega, Karla Alejandra; Gómez Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol Sala, Miguel; Serra Majem, Lluís; Pintó Sala, Xavier; Ros Rahola, Emilio; Lamuela Raventós, Rosa Ma.

Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

Aims Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption (Solanum lycopersicum L.) is associated with systolic and diastolic blood pr...

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Autores:	Murcia-Lesmes, David, Domínguez López, Inés, Laveriano-Santos, Emily P., Tresserra i Rimbau, Anna, Castro-Barquero, Sara, Estruch Riba, Ramon, Vázquez Ruiz, Zenaida, Ruiz Canela, Miguel, Razquin, Cristina, Corella Piquer, Dolores, Sorlí, José V., Salas Salvadó, Jordi, Pérez Vega, Karla Alejandra, Gómez Gracia, Enrique, Lapetra, José, Arós, Fernando, Fiol Sala, Miguel, Serra Majem, Lluís, Pintó Sala, Xavier, Ros Rahola, Emilio, Lamuela Raventós, Rosa Ma.
Tipo de recurso:	artículo
Estado:	Versión publicada
Fecha de publicación:	2023
País:	España
Institución:	Universidad de Barcelona
Repositorio:	Dipòsit Digital de la UB
OAI Identifier:	oai:diposit.ub.edu:2445/208221
Acceso en línea:	https://hdl.handle.net/2445/208221
Access Level:	acceso abierto
Palabra clave:	Cuina mediterrània Tomàquets Malalties cardiovasculars Mediterranean cooking Tomatoes Cardiovascular diseases

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spelling	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trialMurcia-Lesmes, DavidDomínguez López, InésLaveriano-Santos, Emily P.Tresserra i Rimbau, AnnaCastro-Barquero, SaraEstruch Riba, RamonVázquez Ruiz, ZenaidaRuiz Canela, MiguelRazquin, CristinaCorella Piquer, DoloresSorlí, José V.Salas Salvadó, JordiPérez Vega, Karla AlejandraGómez Gracia, EnriqueLapetra, JoséArós, FernandoFiol Sala, MiguelSerra Majem, LluísPintó Sala, XavierRos Rahola, EmilioLamuela Raventós, Rosa Ma.Cuina mediterràniaTomàquetsMalalties cardiovascularsMediterranean cookingTomatoesCardiovascular diseasesAims Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption (Solanum lycopersicum L.) is associated with systolic and diastolic blood pressure, and the risk of hypertension in a prospective 3-year longitudinal study in older adults at high cardiovascular risk. Methods and results The present study was carried out within the PREDIMED (Prevención con Dieta Mediterránea) trial involving 7056 (82.5% hypertensive) participants. The consumption of tomato (g/day) was measured using a validated Food Frequency Questionnaire and categorized into four groups: lowest (<44 g), intermediate (44–82 g), upper-intermediate (82–110 g), and highest (>110 g). Multilevel linear mixed models examined blood pressure and tomato consumption association. Cox proportional-hazards models analysed hypertension risk in 1097 non-hypertensive participants, studying risk reductions vs. the lowest tomato consumers. An inverse association between tomato consumption and diastolic blood pressure was observed between the intermediate group β = −0.65 mmHg [95% confidence interval (CI): −1.20, −0.10] and the lowest consumption group. A significant inverse association was observed for blood pressure in grade 1 hypertension participants in the intermediate tomato consumption group. The risk of hypertension decreased with consumption of >110 g/day tomato (highest vs. lowest consumption; hazard ratio, 0.64 [95% CI, 0.51–0.89]). Conclusion Tomato consumption, including tomato-based products, is beneficial in preventing and managing hypertension. Higher tomato intake reduces hypertension risk by 36%, and moderate consumption lowers blood pressure, especially in grade 1 hypertension.Oxford University Press2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/208221Articles publicats en revistes (Medicina)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1093/eurjpc/zwad363European Journal Of Preventive Cardiology, 2023, vol. 31, num. 8, p. 922-934https://doi.org/10.1093/eurjpc/zwad363cc-by-nc (c) Murcia-Lesmes, David et al., 2023http://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/2082212026-05-27T06:46:51Z
dc.title.none.fl_str_mv	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
title	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
spellingShingle	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial Murcia-Lesmes, David Cuina mediterrània Tomàquets Malalties cardiovasculars Mediterranean cooking Tomatoes Cardiovascular diseases
title_short	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
title_full	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
title_fullStr	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
title_full_unstemmed	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
title_sort	Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial
dc.creator.none.fl_str_mv	Murcia-Lesmes, David Domínguez López, Inés Laveriano-Santos, Emily P. Tresserra i Rimbau, Anna Castro-Barquero, Sara Estruch Riba, Ramon Vázquez Ruiz, Zenaida Ruiz Canela, Miguel Razquin, Cristina Corella Piquer, Dolores Sorlí, José V. Salas Salvadó, Jordi Pérez Vega, Karla Alejandra Gómez Gracia, Enrique Lapetra, José Arós, Fernando Fiol Sala, Miguel Serra Majem, Lluís Pintó Sala, Xavier Ros Rahola, Emilio Lamuela Raventós, Rosa Ma.
author	Murcia-Lesmes, David
author_facet	Murcia-Lesmes, David Domínguez López, Inés Laveriano-Santos, Emily P. Tresserra i Rimbau, Anna Castro-Barquero, Sara Estruch Riba, Ramon Vázquez Ruiz, Zenaida Ruiz Canela, Miguel Razquin, Cristina Corella Piquer, Dolores Sorlí, José V. Salas Salvadó, Jordi Pérez Vega, Karla Alejandra Gómez Gracia, Enrique Lapetra, José Arós, Fernando Fiol Sala, Miguel Serra Majem, Lluís Pintó Sala, Xavier Ros Rahola, Emilio Lamuela Raventós, Rosa Ma.
author_role	author
author2	Domínguez López, Inés Laveriano-Santos, Emily P. Tresserra i Rimbau, Anna Castro-Barquero, Sara Estruch Riba, Ramon Vázquez Ruiz, Zenaida Ruiz Canela, Miguel Razquin, Cristina Corella Piquer, Dolores Sorlí, José V. Salas Salvadó, Jordi Pérez Vega, Karla Alejandra Gómez Gracia, Enrique Lapetra, José Arós, Fernando Fiol Sala, Miguel Serra Majem, Lluís Pintó Sala, Xavier Ros Rahola, Emilio Lamuela Raventós, Rosa Ma.
author2_role	author author author author author author author author author author author author author author author author author author author author
dc.subject.none.fl_str_mv	Cuina mediterrània Tomàquets Malalties cardiovasculars Mediterranean cooking Tomatoes Cardiovascular diseases
topic	Cuina mediterrània Tomàquets Malalties cardiovasculars Mediterranean cooking Tomatoes Cardiovascular diseases
description	Aims Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption (Solanum lycopersicum L.) is associated with systolic and diastolic blood pressure, and the risk of hypertension in a prospective 3-year longitudinal study in older adults at high cardiovascular risk. Methods and results The present study was carried out within the PREDIMED (Prevención con Dieta Mediterránea) trial involving 7056 (82.5% hypertensive) participants. The consumption of tomato (g/day) was measured using a validated Food Frequency Questionnaire and categorized into four groups: lowest (<44 g), intermediate (44–82 g), upper-intermediate (82–110 g), and highest (>110 g). Multilevel linear mixed models examined blood pressure and tomato consumption association. Cox proportional-hazards models analysed hypertension risk in 1097 non-hypertensive participants, studying risk reductions vs. the lowest tomato consumers. An inverse association between tomato consumption and diastolic blood pressure was observed between the intermediate group β = −0.65 mmHg [95% confidence interval (CI): −1.20, −0.10] and the lowest consumption group. A significant inverse association was observed for blood pressure in grade 1 hypertension participants in the intermediate tomato consumption group. The risk of hypertension decreased with consumption of >110 g/day tomato (highest vs. lowest consumption; hazard ratio, 0.64 [95% CI, 0.51–0.89]). Conclusion Tomato consumption, including tomato-based products, is beneficial in preventing and managing hypertension. Higher tomato intake reduces hypertension risk by 36%, and moderate consumption lowers blood pressure, especially in grade 1 hypertension.
publishDate	2023
dc.date.none.fl_str_mv	2023
dc.type.none.fl_str_mv	info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	https://hdl.handle.net/2445/208221
url	https://hdl.handle.net/2445/208221
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.relation.none.fl_str_mv	Reproducció del document publicat a: https://doi.org/10.1093/eurjpc/zwad363 European Journal Of Preventive Cardiology, 2023, vol. 31, num. 8, p. 922-934 https://doi.org/10.1093/eurjpc/zwad363
dc.rights.none.fl_str_mv	cc-by-nc (c) Murcia-Lesmes, David et al., 2023 http://creativecommons.org/licenses/by-nc/4.0/ info:eu-repo/semantics/openAccess
rights_invalid_str_mv	cc-by-nc (c) Murcia-Lesmes, David et al., 2023 http://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.publisher.none.fl_str_mv	Oxford University Press
publisher.none.fl_str_mv	Oxford University Press
dc.source.none.fl_str_mv	Articles publicats en revistes (Medicina) reponame:Dipòsit Digital de la UB instname:Universidad de Barcelona
instname_str	Universidad de Barcelona
reponame_str	Dipòsit Digital de la UB
collection	Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score	15,300724

Association between tomato consumption and blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

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