PRC1 is taking the lead in PcG repression

Polycomb group (PcG) proteins constitute a major epigenetic mechanism for gene repression throughout the plant life. For a long time, the PcG mechanism has been proposed to follow a hierarchical recruitment of PcG repressive complexes (PRCs) to target genes in which the binding of PRC2 and the incor...

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Detalles Bibliográficos
Autores: Merini, Wiam, Calonje Macaya, Myriam
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2015
País:España
Institución:Universidad de Sevilla (US)
Repositorio:idUS. Depósito de Investigación de la Universidad de Sevilla
OAI Identifier:oai:idus.us.es:11441/84509
Acceso en línea:https://hdl.handle.net/11441/84509
https://doi.org/10.1111/tpj.12818
Access Level:acceso abierto
Palabra clave:Arabidopsis
Plant development
Polycomb Group
PRC1
H2A monoubiquitination
Gene repression
Chromatin compaction
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spelling PRC1 is taking the lead in PcG repressionMerini, WiamCalonje Macaya, MyriamArabidopsisPlant developmentPolycomb GroupPRC1H2A monoubiquitinationGene repressionChromatin compactionPolycomb group (PcG) proteins constitute a major epigenetic mechanism for gene repression throughout the plant life. For a long time, the PcG mechanism has been proposed to follow a hierarchical recruitment of PcG repressive complexes (PRCs) to target genes in which the binding of PRC2 and the incorporation of H3 lysine 27 trimethyl marks led to recruitment of PRC1, which in turn mediated H2A monoubiquitination. However, recent studies have turned this model upside‐down by showing that PRC1 activity can be required for PRC2 recruitment and H3K27me3 marking. Here, we review the current knowledge on plant PRC1 composition and mechanisms of repression, as well as its role during plant development.Marie Curie CIG ID 333748 BIO2013-44078-PBlackwell PublishingBioquímica Vegetal y Biología Molecular2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttps://hdl.handle.net/11441/84509https://doi.org/10.1111/tpj.12818reponame:idUS. Depósito de Investigación de la Universidad de Sevillainstname:Universidad de Sevilla (US)InglésPlant Journal, 83 (1), 110-120.ID 333748BIO2013-44078-Phttps://doi.org/10.1111/tpj.12818info:eu-repo/semantics/openAccessoai:idus.us.es:11441/845092026-06-17T12:51:07Z
dc.title.none.fl_str_mv PRC1 is taking the lead in PcG repression
title PRC1 is taking the lead in PcG repression
spellingShingle PRC1 is taking the lead in PcG repression
Merini, Wiam
Arabidopsis
Plant development
Polycomb Group
PRC1
H2A monoubiquitination
Gene repression
Chromatin compaction
title_short PRC1 is taking the lead in PcG repression
title_full PRC1 is taking the lead in PcG repression
title_fullStr PRC1 is taking the lead in PcG repression
title_full_unstemmed PRC1 is taking the lead in PcG repression
title_sort PRC1 is taking the lead in PcG repression
dc.creator.none.fl_str_mv Merini, Wiam
Calonje Macaya, Myriam
author Merini, Wiam
author_facet Merini, Wiam
Calonje Macaya, Myriam
author_role author
author2 Calonje Macaya, Myriam
author2_role author
dc.contributor.none.fl_str_mv Bioquímica Vegetal y Biología Molecular
dc.subject.none.fl_str_mv Arabidopsis
Plant development
Polycomb Group
PRC1
H2A monoubiquitination
Gene repression
Chromatin compaction
topic Arabidopsis
Plant development
Polycomb Group
PRC1
H2A monoubiquitination
Gene repression
Chromatin compaction
description Polycomb group (PcG) proteins constitute a major epigenetic mechanism for gene repression throughout the plant life. For a long time, the PcG mechanism has been proposed to follow a hierarchical recruitment of PcG repressive complexes (PRCs) to target genes in which the binding of PRC2 and the incorporation of H3 lysine 27 trimethyl marks led to recruitment of PRC1, which in turn mediated H2A monoubiquitination. However, recent studies have turned this model upside‐down by showing that PRC1 activity can be required for PRC2 recruitment and H3K27me3 marking. Here, we review the current knowledge on plant PRC1 composition and mechanisms of repression, as well as its role during plant development.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11441/84509
https://doi.org/10.1111/tpj.12818
url https://hdl.handle.net/11441/84509
https://doi.org/10.1111/tpj.12818
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Plant Journal, 83 (1), 110-120.
ID 333748
BIO2013-44078-P
https://doi.org/10.1111/tpj.12818
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Blackwell Publishing
publisher.none.fl_str_mv Blackwell Publishing
dc.source.none.fl_str_mv reponame:idUS. Depósito de Investigación de la Universidad de Sevilla
instname:Universidad de Sevilla (US)
instname_str Universidad de Sevilla (US)
reponame_str idUS. Depósito de Investigación de la Universidad de Sevilla
collection idUS. Depósito de Investigación de la Universidad de Sevilla
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300724

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