Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus

Introduction Soft contact lenses may be a good alternative for early-stage keratoconus (KC) patients who do not tolerate rigid gas permeable (RGP) lenses due to ocular discomfort or complications. This prospective study compared outcomes obtained after 2¿weeks of wearing two types of soft silicone h...

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Autores: Gal, Eyal, Gispets Parcerisas, Joan|||0000-0002-4671-6931, Zyroff, Meira, Netanya, Efrat, Gantz, Liat
Formato: artículo
Fecha de publicación:2024
País:España
Recursos:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/415046
Acesso em linha:https://hdl.handle.net/2117/415046
https://dx.doi.org/10.1111/opo.13331
Access Level:acceso abierto
Palavra-chave:Contact lenses
Keratoconus
Lents de contacte
Queratocon
Àrees temàtiques de la UPC::Ciències de la visió::Contactologia
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repository_id_str
spelling Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconusGal, EyalGispets Parcerisas, Joan|||0000-0002-4671-6931Zyroff, MeiraNetanya, EfratGantz, LiatContact lensesKeratoconusLents de contacteQueratoconÀrees temàtiques de la UPC::Ciències de la visió::ContactologiaIntroduction Soft contact lenses may be a good alternative for early-stage keratoconus (KC) patients who do not tolerate rigid gas permeable (RGP) lenses due to ocular discomfort or complications. This prospective study compared outcomes obtained after 2¿weeks of wearing two types of soft silicone hydrogel contact lenses for keratoconus that varied in their diameter and central thickness (cc). Methods Patients with Amsler–Krumeich grades I or II KC were fitted with small-diameter (14.2 or 14.8¿mm) SoftK (SD-SoftK, cc¿=¿0.48¿mm) and large-diameter (17¿mm) SoftK (LD-SoftK, cc¿=¿0.60¿mm) lenses, each worn for 2¿weeks in a crossover design. Low (10%;10VA) and high (100%;100VA) contrast visual acuity, contrast sensitivity (CS, Pelli-Robson), higher order aberrations (HOAs, Visionix Vx130), the number of trial lens modifications during fitting and the subjectively preferred lens were compared using Friedman tests with post-hoc analysis. Results Forty eyes (N¿=¿20, 10 males, mean age: 39.0¿±¿9.9¿years, range: 23–55¿years) were examined. Their habitual median (interquartile1, interquartile3) 10VA (LogMAR), 100VA (LogMAR) and CS (LogCS) were 0.52 (0.30, 0.50), 0.14 (0.10, 0.15) and 1.35 (1.35, 1.50), respectively. For the SD-SoftK condition, the values were 0.23 (0.17, 0.30), 0.02 (0.00, 0.05) and 1.50 (1.50, 1.65), respectively. For the LD-SoftK condition, the respective values were 0.36 (0.27, 0.44), 0.09 (0.05, 0.13) and 1.50 (1.50, 1.60). SD-SoftK lenses significantly improved 10VA compared with habitual and LD-SoftK. SD-SoftK also significantly improved CS compared with habitual, but not LD-SoftK. LD-SoftK significantly improved spherical aberration compared with uncorrected (0.03¿±¿0.10¿µ vs. 0.07¿±¿0.13¿µ) but not SD-SoftK (0.04¿±¿0.07¿µ). Both lenses required a mean of 1.5 modifications prior to final lens fitting. Fewer adverse events were seen with SD-SoftK (N¿=¿3) compared with LD-SoftK (N¿=¿8), and 75% of participants preferred SD-SoftK lenses. Conclusion SD-SoftK lenses were preferred by 75% of subjects, were associated with fewer adverse events and significantly improved 10VA compared with LD-SoftK lenses. SD-SoftK lenses also significantly improved CS compared with the habitual correction, but this did not differ significantly from the LD-SoftK lenses.Peer Reviewed20242024-01-0120242024-09-27journal articlehttp://purl.org/coar/resource_type/c_6501AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/415046https://dx.doi.org/10.1111/opo.13331reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/4150462026-05-27T15:37:01Z
dc.title.none.fl_str_mv Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
title Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
spellingShingle Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
Gal, Eyal
Contact lenses
Keratoconus
Lents de contacte
Queratocon
Àrees temàtiques de la UPC::Ciències de la visió::Contactologia
title_short Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
title_full Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
title_fullStr Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
title_full_unstemmed Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
title_sort Assessment of large-diameter and small-diameter SoftK specialty contact lenses for early-stage keratoconus
dc.creator.none.fl_str_mv Gal, Eyal
Gispets Parcerisas, Joan|||0000-0002-4671-6931
Zyroff, Meira
Netanya, Efrat
Gantz, Liat
author Gal, Eyal
author_facet Gal, Eyal
Gispets Parcerisas, Joan|||0000-0002-4671-6931
Zyroff, Meira
Netanya, Efrat
Gantz, Liat
author_role author
author2 Gispets Parcerisas, Joan|||0000-0002-4671-6931
Zyroff, Meira
Netanya, Efrat
Gantz, Liat
author2_role author
author
author
author
dc.subject.none.fl_str_mv Contact lenses
Keratoconus
Lents de contacte
Queratocon
Àrees temàtiques de la UPC::Ciències de la visió::Contactologia
topic Contact lenses
Keratoconus
Lents de contacte
Queratocon
Àrees temàtiques de la UPC::Ciències de la visió::Contactologia
description Introduction Soft contact lenses may be a good alternative for early-stage keratoconus (KC) patients who do not tolerate rigid gas permeable (RGP) lenses due to ocular discomfort or complications. This prospective study compared outcomes obtained after 2¿weeks of wearing two types of soft silicone hydrogel contact lenses for keratoconus that varied in their diameter and central thickness (cc). Methods Patients with Amsler–Krumeich grades I or II KC were fitted with small-diameter (14.2 or 14.8¿mm) SoftK (SD-SoftK, cc¿=¿0.48¿mm) and large-diameter (17¿mm) SoftK (LD-SoftK, cc¿=¿0.60¿mm) lenses, each worn for 2¿weeks in a crossover design. Low (10%;10VA) and high (100%;100VA) contrast visual acuity, contrast sensitivity (CS, Pelli-Robson), higher order aberrations (HOAs, Visionix Vx130), the number of trial lens modifications during fitting and the subjectively preferred lens were compared using Friedman tests with post-hoc analysis. Results Forty eyes (N¿=¿20, 10 males, mean age: 39.0¿±¿9.9¿years, range: 23–55¿years) were examined. Their habitual median (interquartile1, interquartile3) 10VA (LogMAR), 100VA (LogMAR) and CS (LogCS) were 0.52 (0.30, 0.50), 0.14 (0.10, 0.15) and 1.35 (1.35, 1.50), respectively. For the SD-SoftK condition, the values were 0.23 (0.17, 0.30), 0.02 (0.00, 0.05) and 1.50 (1.50, 1.65), respectively. For the LD-SoftK condition, the respective values were 0.36 (0.27, 0.44), 0.09 (0.05, 0.13) and 1.50 (1.50, 1.60). SD-SoftK lenses significantly improved 10VA compared with habitual and LD-SoftK. SD-SoftK also significantly improved CS compared with habitual, but not LD-SoftK. LD-SoftK significantly improved spherical aberration compared with uncorrected (0.03¿±¿0.10¿µ vs. 0.07¿±¿0.13¿µ) but not SD-SoftK (0.04¿±¿0.07¿µ). Both lenses required a mean of 1.5 modifications prior to final lens fitting. Fewer adverse events were seen with SD-SoftK (N¿=¿3) compared with LD-SoftK (N¿=¿8), and 75% of participants preferred SD-SoftK lenses. Conclusion SD-SoftK lenses were preferred by 75% of subjects, were associated with fewer adverse events and significantly improved 10VA compared with LD-SoftK lenses. SD-SoftK lenses also significantly improved CS compared with the habitual correction, but this did not differ significantly from the LD-SoftK lenses.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-01-01
2024
2024-09-27
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/415046
https://dx.doi.org/10.1111/opo.13331
url https://hdl.handle.net/2117/415046
https://dx.doi.org/10.1111/opo.13331
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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