State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections

Infectious diseases kill over 17 million people a year, among which bacterial infections stand out. From all the bacterial infections, tuberculosis, diarrhoea, meningitis, pneumonia, sexual transmission diseases and nosocomial infections are the most severe bacterial infections, which affect million...

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Autores: Cano Fernández, Amanda, Ettcheto Arriola, Miren, Espina García, Marta, López-Machado, Ana, Cajal Visa, Yolanda, Rabanal Anglada, Francesc, Sánchez-López, E. (Elena), Camins Espuny, Antoni, García López, María Luisa, Souto, Eliana B.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/171925
Acceso en línea:https://hdl.handle.net/2445/171925
Access Level:acceso abierto
Palabra clave:Malalties bacterianes
Nanopartícules
Nanomedicina
Nanotecnologia
Bacterial diseases
Nanoparticles
Nanomedicine
Nanotechnology
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spelling State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infectionsCano Fernández, AmandaEttcheto Arriola, MirenEspina García, MartaLópez-Machado, AnaCajal Visa, YolandaRabanal Anglada, FrancescSánchez-López, E. (Elena)Camins Espuny, AntoniGarcía López, María LuisaSouto, Eliana B.Malalties bacterianesNanopartículesNanomedicinaNanotecnologiaBacterial diseasesNanoparticlesNanomedicineNanotechnologyInfectious diseases kill over 17 million people a year, among which bacterial infections stand out. From all the bacterial infections, tuberculosis, diarrhoea, meningitis, pneumonia, sexual transmission diseases and nosocomial infections are the most severe bacterial infections, which affect millions of people worldwide. Moreover, the indiscriminate use of antibiotic drugs in the last decades has triggered an increasing multiple resistance towards these drugs, which represent a serious global socioeconomic and public health risk. It is estimated that 33,000 and 35,000 people die yearly in Europe and the United States, respectively, as a direct result of antimicrobial resistance. For all these reasons, there is an emerging need to find novel alternatives to overcome these issues and reduced the morbidity and mortality associated to bacterial infectious diseases. In that sense, nanotechnological approaches, especially smart polymeric nanoparticles, has wrought a revolution in this field, providing an innovative therapeutic alternative able to improve the limitations encountered in available treatments and capable to be effective by theirselves. In this review, we examine the current status of most dangerous human infections, together with an in-depth discussion of the role of nanomedicine to overcome the current disadvantages, and specifically the most recent and innovative studies involving polymeric nanoparticles against most common bacterial infections of the human body.BioMed Central2020info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/171925Articles publicats en revistes (Química Inorgànica i Orgànica)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.1186/s12951-020-00714-2Journal of Nanobiotechnology, 2020, vol. 18, num. 156https://doi.org/10.1186/s12951-020-00714-2cc-by (c) Cano, Amanda et al., 2020http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1719252026-05-27T06:46:51Z
dc.title.none.fl_str_mv State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
title State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
spellingShingle State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
Cano Fernández, Amanda
Malalties bacterianes
Nanopartícules
Nanomedicina
Nanotecnologia
Bacterial diseases
Nanoparticles
Nanomedicine
Nanotechnology
title_short State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
title_full State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
title_fullStr State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
title_full_unstemmed State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
title_sort State-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
dc.creator.none.fl_str_mv Cano Fernández, Amanda
Ettcheto Arriola, Miren
Espina García, Marta
López-Machado, Ana
Cajal Visa, Yolanda
Rabanal Anglada, Francesc
Sánchez-López, E. (Elena)
Camins Espuny, Antoni
García López, María Luisa
Souto, Eliana B.
author Cano Fernández, Amanda
author_facet Cano Fernández, Amanda
Ettcheto Arriola, Miren
Espina García, Marta
López-Machado, Ana
Cajal Visa, Yolanda
Rabanal Anglada, Francesc
Sánchez-López, E. (Elena)
Camins Espuny, Antoni
García López, María Luisa
Souto, Eliana B.
author_role author
author2 Ettcheto Arriola, Miren
Espina García, Marta
López-Machado, Ana
Cajal Visa, Yolanda
Rabanal Anglada, Francesc
Sánchez-López, E. (Elena)
Camins Espuny, Antoni
García López, María Luisa
Souto, Eliana B.
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Malalties bacterianes
Nanopartícules
Nanomedicina
Nanotecnologia
Bacterial diseases
Nanoparticles
Nanomedicine
Nanotechnology
topic Malalties bacterianes
Nanopartícules
Nanomedicina
Nanotecnologia
Bacterial diseases
Nanoparticles
Nanomedicine
Nanotechnology
description Infectious diseases kill over 17 million people a year, among which bacterial infections stand out. From all the bacterial infections, tuberculosis, diarrhoea, meningitis, pneumonia, sexual transmission diseases and nosocomial infections are the most severe bacterial infections, which affect millions of people worldwide. Moreover, the indiscriminate use of antibiotic drugs in the last decades has triggered an increasing multiple resistance towards these drugs, which represent a serious global socioeconomic and public health risk. It is estimated that 33,000 and 35,000 people die yearly in Europe and the United States, respectively, as a direct result of antimicrobial resistance. For all these reasons, there is an emerging need to find novel alternatives to overcome these issues and reduced the morbidity and mortality associated to bacterial infectious diseases. In that sense, nanotechnological approaches, especially smart polymeric nanoparticles, has wrought a revolution in this field, providing an innovative therapeutic alternative able to improve the limitations encountered in available treatments and capable to be effective by theirselves. In this review, we examine the current status of most dangerous human infections, together with an in-depth discussion of the role of nanomedicine to overcome the current disadvantages, and specifically the most recent and innovative studies involving polymeric nanoparticles against most common bacterial infections of the human body.
publishDate 2020
dc.date.none.fl_str_mv 2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/171925
url https://hdl.handle.net/2445/171925
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1186/s12951-020-00714-2
Journal of Nanobiotechnology, 2020, vol. 18, num. 156
https://doi.org/10.1186/s12951-020-00714-2
dc.rights.none.fl_str_mv cc-by (c) Cano, Amanda et al., 2020
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Cano, Amanda et al., 2020
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv Articles publicats en revistes (Química Inorgànica i Orgànica)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301603

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