Diagnosis and management of isthmocele: a SWOT analysis

The purpose of this State-of-the-Art Review was to provide a strategic analysis, in terms of strengths, weaknesses, opportunities and threats (SWOT analysis), of the current evidence regarding the management of uterine isthmocele (Cesarean scar defect). Strengths include the fact that isthmocele can...

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Autores: Domínguez, J.A. (J.A.)|||/items/6bf25cfd-89a3-4b68-81cd-d330681062d5, Alonso-Pacheco, L. (L.)|||/items/39dc3a8b-c52d-486e-a378-1e24c65ed2df, Moratalla, E. (E.)|||/items/f5f02f5c-bc37-4b76-a6d0-516990f42ac8, Carugno, J.A. (J.A)|||/items/e80155c6-3c00-461d-8382-baee4ad714c9, Carrera, M. (M.)|||/items/8d5f049c-2b6f-4fa7-8f81-f7ebac73f331, Perez-Milan, F. (F.)|||/items/b75cfff9-06b2-4835-9c08-acf630fc27c3, Caballero, M. (M.)|||/items/502d1534-7727-4a44-81d4-fee326c3dc45, Alcazar, J.L. (Juan Luis)|||/items/60547d4c-c930-4ef2-a41a-55ae849f2e96
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/67241
Acceso en línea:https://hdl.handle.net/10171/67241
Access Level:acceso abierto
Palabra clave:Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología
Materias Investigacion::Ciencias de la Salud::Cirugía
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spelling Diagnosis and management of isthmocele: a SWOT analysisDomínguez, J.A. (J.A.)|||/items/6bf25cfd-89a3-4b68-81cd-d330681062d5Alonso-Pacheco, L. (L.)|||/items/39dc3a8b-c52d-486e-a378-1e24c65ed2dfMoratalla, E. (E.)|||/items/f5f02f5c-bc37-4b76-a6d0-516990f42ac8Carugno, J.A. (J.A)|||/items/e80155c6-3c00-461d-8382-baee4ad714c9Carrera, M. (M.)|||/items/8d5f049c-2b6f-4fa7-8f81-f7ebac73f331Perez-Milan, F. (F.)|||/items/b75cfff9-06b2-4835-9c08-acf630fc27c3Caballero, M. (M.)|||/items/502d1534-7727-4a44-81d4-fee326c3dc45Alcazar, J.L. (Juan Luis)|||/items/60547d4c-c930-4ef2-a41a-55ae849f2e96Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecologíaMaterias Investigacion::Ciencias de la Salud::CirugíaThe purpose of this State-of-the-Art Review was to provide a strategic analysis, in terms of strengths, weaknesses, opportunities and threats (SWOT analysis), of the current evidence regarding the management of uterine isthmocele (Cesarean scar defect). Strengths include the fact that isthmocele can be diagnosed on two-dimensional transvaginal ultrasound, and that surgical repair may restore natural fertility potential and prevent secondary infertility, as well as reduce the risk of miscarriage and other obstetric complications. However, there is a lack of high-quality evidence regarding the best diagnostic method and criteria, as well as the potential benefits of surgical repair with respect to fertility. There is a need for experienced surgeons skilled in the various isthmocele repair techniques. Isthmocele repair does not prevent the need for Cesarean delivery in subsequent pregnancies. There is increasing awareness regarding the accuracy of transvaginal ultrasound in diagnosing isthmocele. This may lead to surgical correction and prevention of obstetric and perinatal complications in subsequent pregnancies, including Cesarean scar pregnancy. Regarding threats, the existence of different surgical techniques means that there is a risk of selecting an inadequate approach if the type of isthmocele and the patient's characteristics are not considered. There is a risk of overtreatment when asymptomatic defects are repaired surgically. Finally, there is an absence of cost-effectiveness analyses to justify routine repair. Thus, while there are many data suggesting that isthmocele has an adverse effect on both natural fertility and the outcome of assisted reproduction techniques, high-quality evidence to support surgical isthmocele repair in all asymptomatic patients desiring future fertility are lacking. There is increasing agreement to recommend hysteroscopic repair of isthmocele as a first-line approach as long as the residual myometrial thickness is at least 2.5-3.0 mm. © 2023 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.WileyDadun. Depósito Académico Digital Universidad de Navarra20232023-09-1420232023-01-0120232023-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/67241reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/672412026-06-21T12:47:57Z
dc.title.none.fl_str_mv Diagnosis and management of isthmocele: a SWOT analysis
title Diagnosis and management of isthmocele: a SWOT analysis
spellingShingle Diagnosis and management of isthmocele: a SWOT analysis
Domínguez, J.A. (J.A.)|||/items/6bf25cfd-89a3-4b68-81cd-d330681062d5
Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología
Materias Investigacion::Ciencias de la Salud::Cirugía
title_short Diagnosis and management of isthmocele: a SWOT analysis
title_full Diagnosis and management of isthmocele: a SWOT analysis
title_fullStr Diagnosis and management of isthmocele: a SWOT analysis
title_full_unstemmed Diagnosis and management of isthmocele: a SWOT analysis
title_sort Diagnosis and management of isthmocele: a SWOT analysis
dc.creator.none.fl_str_mv Domínguez, J.A. (J.A.)|||/items/6bf25cfd-89a3-4b68-81cd-d330681062d5
Alonso-Pacheco, L. (L.)|||/items/39dc3a8b-c52d-486e-a378-1e24c65ed2df
Moratalla, E. (E.)|||/items/f5f02f5c-bc37-4b76-a6d0-516990f42ac8
Carugno, J.A. (J.A)|||/items/e80155c6-3c00-461d-8382-baee4ad714c9
Carrera, M. (M.)|||/items/8d5f049c-2b6f-4fa7-8f81-f7ebac73f331
Perez-Milan, F. (F.)|||/items/b75cfff9-06b2-4835-9c08-acf630fc27c3
Caballero, M. (M.)|||/items/502d1534-7727-4a44-81d4-fee326c3dc45
Alcazar, J.L. (Juan Luis)|||/items/60547d4c-c930-4ef2-a41a-55ae849f2e96
author Domínguez, J.A. (J.A.)|||/items/6bf25cfd-89a3-4b68-81cd-d330681062d5
author_facet Domínguez, J.A. (J.A.)|||/items/6bf25cfd-89a3-4b68-81cd-d330681062d5
Alonso-Pacheco, L. (L.)|||/items/39dc3a8b-c52d-486e-a378-1e24c65ed2df
Moratalla, E. (E.)|||/items/f5f02f5c-bc37-4b76-a6d0-516990f42ac8
Carugno, J.A. (J.A)|||/items/e80155c6-3c00-461d-8382-baee4ad714c9
Carrera, M. (M.)|||/items/8d5f049c-2b6f-4fa7-8f81-f7ebac73f331
Perez-Milan, F. (F.)|||/items/b75cfff9-06b2-4835-9c08-acf630fc27c3
Caballero, M. (M.)|||/items/502d1534-7727-4a44-81d4-fee326c3dc45
Alcazar, J.L. (Juan Luis)|||/items/60547d4c-c930-4ef2-a41a-55ae849f2e96
author_role author
author2 Alonso-Pacheco, L. (L.)|||/items/39dc3a8b-c52d-486e-a378-1e24c65ed2df
Moratalla, E. (E.)|||/items/f5f02f5c-bc37-4b76-a6d0-516990f42ac8
Carugno, J.A. (J.A)|||/items/e80155c6-3c00-461d-8382-baee4ad714c9
Carrera, M. (M.)|||/items/8d5f049c-2b6f-4fa7-8f81-f7ebac73f331
Perez-Milan, F. (F.)|||/items/b75cfff9-06b2-4835-9c08-acf630fc27c3
Caballero, M. (M.)|||/items/502d1534-7727-4a44-81d4-fee326c3dc45
Alcazar, J.L. (Juan Luis)|||/items/60547d4c-c930-4ef2-a41a-55ae849f2e96
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Dadun. Depósito Académico Digital Universidad de Navarra
dc.subject.none.fl_str_mv Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología
Materias Investigacion::Ciencias de la Salud::Cirugía
topic Materias Investigacion::Ciencias de la Salud::Obstetricia y ginecología
Materias Investigacion::Ciencias de la Salud::Cirugía
description The purpose of this State-of-the-Art Review was to provide a strategic analysis, in terms of strengths, weaknesses, opportunities and threats (SWOT analysis), of the current evidence regarding the management of uterine isthmocele (Cesarean scar defect). Strengths include the fact that isthmocele can be diagnosed on two-dimensional transvaginal ultrasound, and that surgical repair may restore natural fertility potential and prevent secondary infertility, as well as reduce the risk of miscarriage and other obstetric complications. However, there is a lack of high-quality evidence regarding the best diagnostic method and criteria, as well as the potential benefits of surgical repair with respect to fertility. There is a need for experienced surgeons skilled in the various isthmocele repair techniques. Isthmocele repair does not prevent the need for Cesarean delivery in subsequent pregnancies. There is increasing awareness regarding the accuracy of transvaginal ultrasound in diagnosing isthmocele. This may lead to surgical correction and prevention of obstetric and perinatal complications in subsequent pregnancies, including Cesarean scar pregnancy. Regarding threats, the existence of different surgical techniques means that there is a risk of selecting an inadequate approach if the type of isthmocele and the patient's characteristics are not considered. There is a risk of overtreatment when asymptomatic defects are repaired surgically. Finally, there is an absence of cost-effectiveness analyses to justify routine repair. Thus, while there are many data suggesting that isthmocele has an adverse effect on both natural fertility and the outcome of assisted reproduction techniques, high-quality evidence to support surgical isthmocele repair in all asymptomatic patients desiring future fertility are lacking. There is increasing agreement to recommend hysteroscopic repair of isthmocele as a first-line approach as long as the residual myometrial thickness is at least 2.5-3.0 mm. © 2023 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-09-14
2023
2023-01-01
2023
2023-01-01
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eng
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eu_rights_str_mv openAccess
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