Three-blind validation strategy of deep learning models for image segmentation

Image segmentation plays a central role in computer vision applications such as medical imaging, industrial inspection, and environmental monitoring. However, evaluating segmentation performance can be particularly challenging when ground truth is not clearly defined, as is often the case in tasks i...

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Detalles Bibliográficos
Autores: Larroza, Andrés, Pérez-Benito, Francisco Javier, Tendero, Raquel, Pérez Cortés, Juan Carlos, 1966-, Román, Marta, Llobet, Rafael
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:dnet:rdupf_______::9ee43c88c3e03df2884fddfa25730c73
Acceso en línea:https://hdl.handle.net/10230/73375
http://dx.doi.org/10.3390/jimaging11050170
Access Level:acceso abierto
Palabra clave:Deep learning
Image segmentation
Mammography
Descripción
Sumario:Image segmentation plays a central role in computer vision applications such as medical imaging, industrial inspection, and environmental monitoring. However, evaluating segmentation performance can be particularly challenging when ground truth is not clearly defined, as is often the case in tasks involving subjective interpretation. These challenges are amplified by inter- and intra-observer variability, which complicates the use of human annotations as a reliable reference. To address this, we propose a novel validation framework-referred to as the three-blind validation strategy-that enables rigorous assessment of segmentation models in contexts where subjectivity and label variability are significant. The core idea is to have a third independent expert, blind to the labeler identities, assess a shuffled set of segmentations produced by multiple human annotators and/or automated models. This allows for the unbiased evaluation of model performance and helps uncover patterns of disagreement that may indicate systematic issues with either human or machine annotations. The primary objective of this study is to introduce and demonstrate this validation strategy as a generalizable framework for robust model evaluation in subjective segmentation tasks. We illustrate its practical implementation in a mammography use case involving dense tissue segmentation while emphasizing its potential applicability to a broad range of segmentation scenarios.