Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing

[EN] Colloidal lead halide perovskite nanocrystals are highly luminescent materials with great promise as fluorescent probes in biosensing as long as their intrinsic instability in aqueous media is effectively addressed. In this study, we successfully prepared stable and multicolored CsPbX3@SiO2 (X...

Descripción completa

Detalles Bibliográficos
Autores: Collantes-Pablo, Cynthia, Teixeira, William|||0000-0002-6729-9508, González-Pedro, Victoria|||0000-0002-8133-5958, Bañuls Polo, María-José|||0000-0002-2422-7731, Quintero-Campos, Pedro|||0000-0002-9398-5077, Morais, Sergi|||0000-0002-3722-2358, Maquieira, Angel|||0000-0003-4641-4957
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/211077
Acceso en línea:https://riunet.upv.es/handle/10251/211077
Access Level:acceso abierto
Palabra clave:Water-assisted synthesis
Core shell nanoparticles
Isolated nanospheres
Photoluminescence
QUIMICA ANALITICA
id ES_fe5960df308f5efbcdb231c85846ddf9
oai_identifier_str oai:riunet.upv.es:10251/211077
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
title Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
spellingShingle Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
Collantes-Pablo, Cynthia
Water-assisted synthesis
Core shell nanoparticles
Isolated nanospheres
Photoluminescence
QUIMICA ANALITICA
title_short Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
title_full Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
title_fullStr Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
title_full_unstemmed Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
title_sort Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensing
dc.creator.none.fl_str_mv Collantes-Pablo, Cynthia
Teixeira, William|||0000-0002-6729-9508
González-Pedro, Victoria|||0000-0002-8133-5958
Bañuls Polo, María-José|||0000-0002-2422-7731
Quintero-Campos, Pedro|||0000-0002-9398-5077
Morais, Sergi|||0000-0002-3722-2358
Maquieira, Angel|||0000-0003-4641-4957
author Collantes-Pablo, Cynthia
author_facet Collantes-Pablo, Cynthia
Teixeira, William|||0000-0002-6729-9508
González-Pedro, Victoria|||0000-0002-8133-5958
Bañuls Polo, María-José|||0000-0002-2422-7731
Quintero-Campos, Pedro|||0000-0002-9398-5077
Morais, Sergi|||0000-0002-3722-2358
Maquieira, Angel|||0000-0003-4641-4957
author_role author
author2 Teixeira, William|||0000-0002-6729-9508
González-Pedro, Victoria|||0000-0002-8133-5958
Bañuls Polo, María-José|||0000-0002-2422-7731
Quintero-Campos, Pedro|||0000-0002-9398-5077
Morais, Sergi|||0000-0002-3722-2358
Maquieira, Angel|||0000-0003-4641-4957
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Escuela Técnica Superior de Ingeniería Aeroespacial y Diseño Industrial
Departamento de Química
Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico
Escuela Técnica Superior de Ingeniería Agronómica y del Medio Natural
GENERALITAT VALENCIANA
Agencia Estatal de Investigación
UNIVERSIDAD POLITECNICA DE VALENCIA
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Water-assisted synthesis
Core shell nanoparticles
Isolated nanospheres
Photoluminescence
QUIMICA ANALITICA
topic Water-assisted synthesis
Core shell nanoparticles
Isolated nanospheres
Photoluminescence
QUIMICA ANALITICA
description [EN] Colloidal lead halide perovskite nanocrystals are highly luminescent materials with great promise as fluorescent probes in biosensing as long as their intrinsic instability in aqueous media is effectively addressed. In this study, we successfully prepared stable and multicolored CsPbX3@SiO2 (X = Cl/Br, Br and I) core¿ shell nanoparticles through a simple method based on the water-induced transformation of Cs4PbX6 into CsPbX3, combined with sol¿gel procedures. We observed that the concentration of the Cs4PbX6 precursor plays a crucial role in the formation of isolated nanospheres with uniform silica coating and in controlling the number of core-free particles. Furthermore, our research expands this approach to other halide compositions, resulting in multicolored core¿shell nanoparticles with emission wavelengths ranging from 490 to 700 nm, average sizes below 30 nm, and photoluminescence quantum yields close to 60%. Unlike in previous reports, the silica coating boosts the photoluminescence quantum yields compared to uncoated counterparts and provides increased structural stability for more than four days. Moreover, a controlled thermal treatment confers water stability to the as-synthesized nanoparticles. To establish the feasibility of the developed materials as fluorescent probes, we successfully demonstrated their specific recognition of a humanized antibody (omalizumab) used in treating patients with severe allergic asthma. This work paves the way to develop in vitro tests using CsPbX3@SiO2 core¿shell nanoparticles as fluorogenic probes.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-11-15
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/211077
url https://riunet.upv.es/handle/10251/211077
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PID2019-110713RB-I00 HACIA EL BIOSENSADO HOLOGRAFICO AVANZADO
Universitat Politècnica de València https://doi.org/10.13039/501100004233 PAID-01-19-06 Explorando las nanopartículas de perovskita de haluros metálicos como elementos de biosensado: desde agentes de contraste fluorescentes hasta transductores ópticos.
Generalitat Valenciana https://doi.org/10.13039/501100003359 PROMETEO%2F2020%2F094 HOLOGRAFÍA. UNA VIA PARA AFRONTAR NUEVOS RETOS EN BIOSENSADO
Agencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 BES-2017-080242 AYUDAS PARA CONTRATOS PREDOCTORALES PARA LA FORMACION DE DOCTORES-COLLANTES PABLO
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv The Royal Society of Chemistry
publisher.none.fl_str_mv The Royal Society of Chemistry
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869425676859211776
spelling Water-assisted synthesis of stable and multicolored CsPbX3@SiO2 core shell nanoparticles as fluorescent probes for biosensingCollantes-Pablo, CynthiaTeixeira, William|||0000-0002-6729-9508González-Pedro, Victoria|||0000-0002-8133-5958Bañuls Polo, María-José|||0000-0002-2422-7731Quintero-Campos, Pedro|||0000-0002-9398-5077Morais, Sergi|||0000-0002-3722-2358Maquieira, Angel|||0000-0003-4641-4957Water-assisted synthesisCore shell nanoparticlesIsolated nanospheresPhotoluminescenceQUIMICA ANALITICA[EN] Colloidal lead halide perovskite nanocrystals are highly luminescent materials with great promise as fluorescent probes in biosensing as long as their intrinsic instability in aqueous media is effectively addressed. In this study, we successfully prepared stable and multicolored CsPbX3@SiO2 (X = Cl/Br, Br and I) core¿ shell nanoparticles through a simple method based on the water-induced transformation of Cs4PbX6 into CsPbX3, combined with sol¿gel procedures. We observed that the concentration of the Cs4PbX6 precursor plays a crucial role in the formation of isolated nanospheres with uniform silica coating and in controlling the number of core-free particles. Furthermore, our research expands this approach to other halide compositions, resulting in multicolored core¿shell nanoparticles with emission wavelengths ranging from 490 to 700 nm, average sizes below 30 nm, and photoluminescence quantum yields close to 60%. Unlike in previous reports, the silica coating boosts the photoluminescence quantum yields compared to uncoated counterparts and provides increased structural stability for more than four days. Moreover, a controlled thermal treatment confers water stability to the as-synthesized nanoparticles. To establish the feasibility of the developed materials as fluorescent probes, we successfully demonstrated their specific recognition of a humanized antibody (omalizumab) used in treating patients with severe allergic asthma. This work paves the way to develop in vitro tests using CsPbX3@SiO2 core¿shell nanoparticles as fluorogenic probes.This work was financially supported by the E.U FEDER project ADBIHOL/AEI/10.13039/501100011033 from MCIN/AEI and PROMETEO/2020/094 from Generalitat Valenciana. C. C. thanks the Spanish Ministry of Economy and Competitiveness for her predoctoral contract (BES-2017-080242). W. T. acknowledges the financial support from Universitat Politécnica de Valéncia for the Ph.D. studies (PAID-01-19-06).The Royal Society of ChemistryEscuela Técnica Superior de Ingeniería Aeroespacial y Diseño IndustrialDepartamento de QuímicaInstituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo TecnológicoEscuela Técnica Superior de Ingeniería Agronómica y del Medio NaturalGENERALITAT VALENCIANAAgencia Estatal de InvestigaciónUNIVERSIDAD POLITECNICA DE VALENCIARepositorio Institucional de la Universitat Politècnica de València Riunet20232023-11-15journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/211077reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 PID2019-110713RB-I00 HACIA EL BIOSENSADO HOLOGRAFICO AVANZADOUniversitat Politècnica de València https://doi.org/10.13039/501100004233 PAID-01-19-06 Explorando las nanopartículas de perovskita de haluros metálicos como elementos de biosensado: desde agentes de contraste fluorescentes hasta transductores ópticos.Generalitat Valenciana https://doi.org/10.13039/501100003359 PROMETEO%2F2020%2F094 HOLOGRAFÍA. UNA VIA PARA AFRONTAR NUEVOS RETOS EN BIOSENSADOAgencia Estatal de Investigación http://dx.doi.org/10.13039/501100011033 BES-2017-080242 AYUDAS PARA CONTRATOS PREDOCTORALES PARA LA FORMACION DE DOCTORES-COLLANTES PABLOopen accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento (by)http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/2110772026-06-13T07:49:27Z
score 15,812429

Similares en LA Referencia