Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices
Atrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with implantable devices and AF episodes. Observational multicentre study (51 centres) i...
| Autores: | , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Universitat Autònoma de Barcelona |
| Repositorio: | Dipòsit Digital de Documents de la UAB |
| Idioma: | inglés |
| OAI Identifier: | oai:ddd.uab.cat:283893 |
| Acceso en línea: | https://ddd.uab.cat/record/283893 https://dx.doi.org/urn:doi:10.1093/europace/euz331 |
| Access Level: | acceso abierto |
| Palabra clave: | Atrial fibrillation Atrial fibrillation progression Electrical remodeling Ehealth Implantable cardioverter-defibrillator Mobile health Telemedicine |
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Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devicesLillo-Castellano, José MaríaGonzález-Ferrer, Juan JoséMarina-Breysse, ManuelMartínez-Ferrer, José Bautista|||0000-0002-5397-3995Pérez-Álvarez, LuisaAlzueta, JavierMartínez, Juan GabrielRodríguez, AníbalRodríguez-Pérez, Juan CarlosAnguera, Ignasi|||0000-0001-6988-3487Viñolas, Xavier|||0000-0002-8243-1271García-Alberola, Arcadio|||0000-0003-1928-865XQuintanilla, Jorge G.|||0000-0002-2227-3507Alfonso-Almazán, José ManuelGarcía, JavierBorrego, LuisCañadas-Godoy, VictoriaPérez-Castellano, NicasioPérez-Villacastín, Julián|||0000-0002-4867-3912Jiménez-Díaz, JavierJalife, JoséFilgueiras-Rama, David|||0000-0001-5909-2454Atrial fibrillationAtrial fibrillation progressionElectrical remodelingEhealthImplantable cardioverter-defibrillatorMobile healthTelemedicineAtrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with implantable devices and AF episodes. Observational multicentre study (51 centres) including 4618 patients with implantable cardioverter-defibrillator and results þ/resynchronization therapy (ICD/CRT-D) and 352 patients (2 centres) with pacemakers (median follow-up: 3.4 years). Atrial activation rate (AAR) was quantified as the frequency of the dominant peak in the signal spectrum of AF episodes with atrial bipolar electrograms. Patients with complete progression of AER, from paroxysmal AF episodes to electrically remodelled persistent AF, were used to depict patient-specific AER slopes. A total of 34 712 AF tracings from 830 patients (87 with pacemakers) were suitable for the study. Complete progression of AER was documented in 216 patients (16 with pacemakers). Patients with persistent AF after completion of AER showed ∼30% faster AAR than patients with paroxysmal AF. The slope of AAR changes during AF progression revealed patient-specific patterns that correlated with the time-to-completion of AER (R = 0.85). Pacemaker patients were older than patients with ICD/CRT-Ds (78.3 vs. 67.2 year olds, respectively, P < 0.001) and had a shorter median time-to-completion of AER (24.9 vs. 93.5 days, respectively, P = 0.016). Remote transmissions in patients with ICD/CRT-D devices enabled the estimation of the time-to-completion of AER using the predicted slope of AAR changes from initiation to completion of electrical remodelling (R = 0.45). The AF progression shows patient-specific patterns of AER, which can be estimated using available remote-monitoring technology.Universitat Autònoma de Barcelona 22020-01-0120202020-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/283893https://dx.doi.org/urn:doi:10.1093/europace/euz331reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengMinisterio de Economía y Competitividad https://doi.org/10.13039/501100003329 SEV-2015-0505Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 CB16/11/00458open accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:2838932026-06-06T12:50:31Z |
| dc.title.none.fl_str_mv |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| title |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| spellingShingle |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices Lillo-Castellano, José María Atrial fibrillation Atrial fibrillation progression Electrical remodeling Ehealth Implantable cardioverter-defibrillator Mobile health Telemedicine |
| title_short |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| title_full |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| title_fullStr |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| title_full_unstemmed |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| title_sort |
Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices |
| dc.creator.none.fl_str_mv |
Lillo-Castellano, José María González-Ferrer, Juan José Marina-Breysse, Manuel Martínez-Ferrer, José Bautista|||0000-0002-5397-3995 Pérez-Álvarez, Luisa Alzueta, Javier Martínez, Juan Gabriel Rodríguez, Aníbal Rodríguez-Pérez, Juan Carlos Anguera, Ignasi|||0000-0001-6988-3487 Viñolas, Xavier|||0000-0002-8243-1271 García-Alberola, Arcadio|||0000-0003-1928-865X Quintanilla, Jorge G.|||0000-0002-2227-3507 Alfonso-Almazán, José Manuel García, Javier Borrego, Luis Cañadas-Godoy, Victoria Pérez-Castellano, Nicasio Pérez-Villacastín, Julián|||0000-0002-4867-3912 Jiménez-Díaz, Javier Jalife, José Filgueiras-Rama, David|||0000-0001-5909-2454 |
| author |
Lillo-Castellano, José María |
| author_facet |
Lillo-Castellano, José María González-Ferrer, Juan José Marina-Breysse, Manuel Martínez-Ferrer, José Bautista|||0000-0002-5397-3995 Pérez-Álvarez, Luisa Alzueta, Javier Martínez, Juan Gabriel Rodríguez, Aníbal Rodríguez-Pérez, Juan Carlos Anguera, Ignasi|||0000-0001-6988-3487 Viñolas, Xavier|||0000-0002-8243-1271 García-Alberola, Arcadio|||0000-0003-1928-865X Quintanilla, Jorge G.|||0000-0002-2227-3507 Alfonso-Almazán, José Manuel García, Javier Borrego, Luis Cañadas-Godoy, Victoria Pérez-Castellano, Nicasio Pérez-Villacastín, Julián|||0000-0002-4867-3912 Jiménez-Díaz, Javier Jalife, José Filgueiras-Rama, David|||0000-0001-5909-2454 |
| author_role |
author |
| author2 |
González-Ferrer, Juan José Marina-Breysse, Manuel Martínez-Ferrer, José Bautista|||0000-0002-5397-3995 Pérez-Álvarez, Luisa Alzueta, Javier Martínez, Juan Gabriel Rodríguez, Aníbal Rodríguez-Pérez, Juan Carlos Anguera, Ignasi|||0000-0001-6988-3487 Viñolas, Xavier|||0000-0002-8243-1271 García-Alberola, Arcadio|||0000-0003-1928-865X Quintanilla, Jorge G.|||0000-0002-2227-3507 Alfonso-Almazán, José Manuel García, Javier Borrego, Luis Cañadas-Godoy, Victoria Pérez-Castellano, Nicasio Pérez-Villacastín, Julián|||0000-0002-4867-3912 Jiménez-Díaz, Javier Jalife, José Filgueiras-Rama, David|||0000-0001-5909-2454 |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universitat Autònoma de Barcelona |
| dc.subject.none.fl_str_mv |
Atrial fibrillation Atrial fibrillation progression Electrical remodeling Ehealth Implantable cardioverter-defibrillator Mobile health Telemedicine |
| topic |
Atrial fibrillation Atrial fibrillation progression Electrical remodeling Ehealth Implantable cardioverter-defibrillator Mobile health Telemedicine |
| description |
Atrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with implantable devices and AF episodes. Observational multicentre study (51 centres) including 4618 patients with implantable cardioverter-defibrillator and results þ/resynchronization therapy (ICD/CRT-D) and 352 patients (2 centres) with pacemakers (median follow-up: 3.4 years). Atrial activation rate (AAR) was quantified as the frequency of the dominant peak in the signal spectrum of AF episodes with atrial bipolar electrograms. Patients with complete progression of AER, from paroxysmal AF episodes to electrically remodelled persistent AF, were used to depict patient-specific AER slopes. A total of 34 712 AF tracings from 830 patients (87 with pacemakers) were suitable for the study. Complete progression of AER was documented in 216 patients (16 with pacemakers). Patients with persistent AF after completion of AER showed ∼30% faster AAR than patients with paroxysmal AF. The slope of AAR changes during AF progression revealed patient-specific patterns that correlated with the time-to-completion of AER (R = 0.85). Pacemaker patients were older than patients with ICD/CRT-Ds (78.3 vs. 67.2 year olds, respectively, P < 0.001) and had a shorter median time-to-completion of AER (24.9 vs. 93.5 days, respectively, P = 0.016). Remote transmissions in patients with ICD/CRT-D devices enabled the estimation of the time-to-completion of AER using the predicted slope of AAR changes from initiation to completion of electrical remodelling (R = 0.45). The AF progression shows patient-specific patterns of AER, which can be estimated using available remote-monitoring technology. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2 2020-01-01 2020 2020-01-01 |
| dc.type.none.fl_str_mv |
Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
https://ddd.uab.cat/record/283893 https://dx.doi.org/urn:doi:10.1093/europace/euz331 |
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https://ddd.uab.cat/record/283893 https://dx.doi.org/urn:doi:10.1093/europace/euz331 |
| dc.language.none.fl_str_mv |
Inglés eng |
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Inglés |
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eng |
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Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 SEV-2015-0505 Ministerio de Economía y Competitividad https://doi.org/10.13039/501100003329 CB16/11/00458 |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc/4.0/ |
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openAccess |
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application/pdf |
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reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona |
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Universitat Autònoma de Barcelona |
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