Image_4_CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukemia: frequency, phenotype and association with disease progression.pdf [Dataset]

[Introduction]: In monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation. CD20+ T cells are a subpopulation of T cells that appear...

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Detalhes bibliográficos
Autores: Rodrigues, Cristiana, Laranjeira, Paula, Pinho, Aryane, Silva, Isabel, Silva, Sandra, Coucelo, Margarida, Oliveira, Ana C., Simões, Ana Teresa, Damásio, Inês, Matos Silva, Helena, Urbano, Mafalda, Sarmento-Ribeiro, Ana Bela, Geraldes, Catarina, Domingues, M. Rosário, Almeida, Julia, Criado, Ignacio, Orfao, Alberto, Paiva, Artur
Formato: conjunto de datos
Estado:Versión publicada
Fecha de publicación:2024
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/370217
Acesso em linha:http://hdl.handle.net/10261/370217
Access Level:acceso abierto
Palavra-chave:CD20+ T cells
Chronic lymphocytic leukemia
Monoclonal B lymphocytosis
Immunoglobulin heavy chain variable region
T cell polarization
Descrição
Resumo:[Introduction]: In monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation. CD20+ T cells are a subpopulation of T cells that appear to be involved in autoimmune diseases and cancer.