Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study

Objectives: One of Africa's most important challenges is to improve maternal and neonatal health. The identification of groups at highest risk for adverse pregnancy outcomes is important for developing and implementing targeted prevention programmes. This study assessed whether young adolescent...

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Autores: Mombo-Ngoma, Ghyslain, Mackanga, Jean Rodolphe, González, Raquel, Ouédraogo, Smaila, Kakolwa, Mwaka A., Zoleko-Manego, Rella, Basra, Arti, Rupérez, María, Cot, Michel, Kabanywanyi, Abdunoor M., Matsiegui, Pierre-Blaise, Agnandji, Selidji Todagbe, Vala, Anifa, Massougbodji, Achille, Abdulla, Salim, Adegnika, Ayôla A., Sevene, Esperança Júlia Pires, Macete, Eusebio Víctor, Yazdanbakhsh, Maria, Kremsner, Peter G., Aponte, John J., Menéndez, Clara, Ramharter, Michael
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2016
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/100568
Acesso em linha:https://hdl.handle.net/2445/100568
Access Level:Acceso aberto
Palavra-chave:Adolescents
Noies
Embaràs
Àfrica subsahariana
Teenagers
Girls
Pregnancy
Sub-Saharan Africa
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spelling Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry studyMombo-Ngoma, GhyslainMackanga, Jean RodolpheGonzález, RaquelOuédraogo, SmailaKakolwa, Mwaka A.Zoleko-Manego, RellaBasra, ArtiRupérez, MaríaCot, MichelKabanywanyi, Abdunoor M.Matsiegui, Pierre-BlaiseAgnandji, Selidji TodagbeVala, AnifaMassougbodji, AchilleAbdulla, SalimAdegnika, Ayôla A.Sevene, Esperança Júlia PiresMacete, Eusebio VíctorYazdanbakhsh, MariaKremsner, Peter G.Aponte, John J.Menéndez, ClaraRamharter, MichaelAdolescentsNoiesEmbaràsÀfrica subsaharianaTeenagersGirlsPregnancySub-Saharan AfricaObjectives: One of Africa's most important challenges is to improve maternal and neonatal health. The identification of groups at highest risk for adverse pregnancy outcomes is important for developing and implementing targeted prevention programmes. This study assessed whether young adolescent girls constitute a group at increased risk for adverse birth outcomes among pregnant women in sub-Saharan Africa. Setting: Data were collected prospectively as part of a large randomised controlled clinical trial evaluating intermittent preventive treatment of malaria in pregnancy (NCT00811421—Clinical Trials.gov), conducted between September 2009 and December 2013 in Benin, Gabon, Mozambique and Tanzania. Participants: Of 4749 participants, pregnancy outcomes were collected for 4388 deliveries with 4183 live births including 83 multiple gestations. Of 4100 mothers with a singleton live birth delivery, 24% (975/4100) were adolescents (≤19 years of age) and 6% (248/4100) were aged ≤16 years. Primary and secondary outcome measures: Primary outcomes of this predefined analysis were preterm delivery and low birth weight. Results: The overall prevalence of low birthweight infants and preterm delivery was 10% (371/3851) and 4% (159/3862), respectively. Mothers aged ≤16 years showed higher risk for the delivery of a low birthweight infant (OR: 1.96; 95% CI 1.35 to 2.83). Similarly, preterm delivery was associated with young maternal age (≤16 years; OR: 2.62; 95% CI 1.59 to 4.30). In a subanalysis restricted to primiparous women: preterm delivery, OR 4.28; 95% CI 2.05 to 8.93; low birth weight, OR: 1.29; 95% CI 0.82 to 2.01. Conclusions: Young maternal age increases the risk for adverse pregnancy outcomes and it is a stronger predictor for low birth weight and preterm delivery than other established risk factors in sub-Saharan Africa. This finding highlights the need to improve adolescent reproductive health in sub-Saharan Africa.BMJ Journals2016201620162016info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion9 p.application/pdfhttps://hdl.handle.net/2445/100568Articles publicats en revistes (ISGlobal)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: http://dx.doi.org/10.1136/bmjopen-2016-011783BMJ Open, 2016, vol. 6, num. 6, p. e011783http://dx.doi.org/10.1136/bmjopen-2016-011783cc by (c) Mombo-Ngoma et al., 2016http://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1005682026-05-29T05:05:01Z
dc.title.none.fl_str_mv Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
title Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
spellingShingle Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
Mombo-Ngoma, Ghyslain
Adolescents
Noies
Embaràs
Àfrica subsahariana
Teenagers
Girls
Pregnancy
Sub-Saharan Africa
title_short Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
title_full Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
title_fullStr Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
title_full_unstemmed Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
title_sort Young adolescent girls are at high risk for adverse pregnancy outcomes in sub-Saharan Africa: an observational multicountry study
dc.creator.none.fl_str_mv Mombo-Ngoma, Ghyslain
Mackanga, Jean Rodolphe
González, Raquel
Ouédraogo, Smaila
Kakolwa, Mwaka A.
Zoleko-Manego, Rella
Basra, Arti
Rupérez, María
Cot, Michel
Kabanywanyi, Abdunoor M.
Matsiegui, Pierre-Blaise
Agnandji, Selidji Todagbe
Vala, Anifa
Massougbodji, Achille
Abdulla, Salim
Adegnika, Ayôla A.
Sevene, Esperança Júlia Pires
Macete, Eusebio Víctor
Yazdanbakhsh, Maria
Kremsner, Peter G.
Aponte, John J.
Menéndez, Clara
Ramharter, Michael
author Mombo-Ngoma, Ghyslain
author_facet Mombo-Ngoma, Ghyslain
Mackanga, Jean Rodolphe
González, Raquel
Ouédraogo, Smaila
Kakolwa, Mwaka A.
Zoleko-Manego, Rella
Basra, Arti
Rupérez, María
Cot, Michel
Kabanywanyi, Abdunoor M.
Matsiegui, Pierre-Blaise
Agnandji, Selidji Todagbe
Vala, Anifa
Massougbodji, Achille
Abdulla, Salim
Adegnika, Ayôla A.
Sevene, Esperança Júlia Pires
Macete, Eusebio Víctor
Yazdanbakhsh, Maria
Kremsner, Peter G.
Aponte, John J.
Menéndez, Clara
Ramharter, Michael
author_role author
author2 Mackanga, Jean Rodolphe
González, Raquel
Ouédraogo, Smaila
Kakolwa, Mwaka A.
Zoleko-Manego, Rella
Basra, Arti
Rupérez, María
Cot, Michel
Kabanywanyi, Abdunoor M.
Matsiegui, Pierre-Blaise
Agnandji, Selidji Todagbe
Vala, Anifa
Massougbodji, Achille
Abdulla, Salim
Adegnika, Ayôla A.
Sevene, Esperança Júlia Pires
Macete, Eusebio Víctor
Yazdanbakhsh, Maria
Kremsner, Peter G.
Aponte, John J.
Menéndez, Clara
Ramharter, Michael
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Adolescents
Noies
Embaràs
Àfrica subsahariana
Teenagers
Girls
Pregnancy
Sub-Saharan Africa
topic Adolescents
Noies
Embaràs
Àfrica subsahariana
Teenagers
Girls
Pregnancy
Sub-Saharan Africa
description Objectives: One of Africa's most important challenges is to improve maternal and neonatal health. The identification of groups at highest risk for adverse pregnancy outcomes is important for developing and implementing targeted prevention programmes. This study assessed whether young adolescent girls constitute a group at increased risk for adverse birth outcomes among pregnant women in sub-Saharan Africa. Setting: Data were collected prospectively as part of a large randomised controlled clinical trial evaluating intermittent preventive treatment of malaria in pregnancy (NCT00811421—Clinical Trials.gov), conducted between September 2009 and December 2013 in Benin, Gabon, Mozambique and Tanzania. Participants: Of 4749 participants, pregnancy outcomes were collected for 4388 deliveries with 4183 live births including 83 multiple gestations. Of 4100 mothers with a singleton live birth delivery, 24% (975/4100) were adolescents (≤19 years of age) and 6% (248/4100) were aged ≤16 years. Primary and secondary outcome measures: Primary outcomes of this predefined analysis were preterm delivery and low birth weight. Results: The overall prevalence of low birthweight infants and preterm delivery was 10% (371/3851) and 4% (159/3862), respectively. Mothers aged ≤16 years showed higher risk for the delivery of a low birthweight infant (OR: 1.96; 95% CI 1.35 to 2.83). Similarly, preterm delivery was associated with young maternal age (≤16 years; OR: 2.62; 95% CI 1.59 to 4.30). In a subanalysis restricted to primiparous women: preterm delivery, OR 4.28; 95% CI 2.05 to 8.93; low birth weight, OR: 1.29; 95% CI 0.82 to 2.01. Conclusions: Young maternal age increases the risk for adverse pregnancy outcomes and it is a stronger predictor for low birth weight and preterm delivery than other established risk factors in sub-Saharan Africa. This finding highlights the need to improve adolescent reproductive health in sub-Saharan Africa.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016
2016
2016
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/100568
url https://hdl.handle.net/2445/100568
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: http://dx.doi.org/10.1136/bmjopen-2016-011783
BMJ Open, 2016, vol. 6, num. 6, p. e011783
http://dx.doi.org/10.1136/bmjopen-2016-011783
dc.rights.none.fl_str_mv cc by (c) Mombo-Ngoma et al., 2016
http://creativecommons.org/licenses/by/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by (c) Mombo-Ngoma et al., 2016
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9 p.
application/pdf
dc.publisher.none.fl_str_mv BMJ Journals
publisher.none.fl_str_mv BMJ Journals
dc.source.none.fl_str_mv Articles publicats en revistes (ISGlobal)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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