Triplex-stabilizing properties of parallel clamps carrying LNA derivatives at the Hoogsteen strand
DNA Parallel clamps with a polypurine strand linked to a polypyrimidine Hoogsteen strand containing locked nucleic acids bind their corresponding polypyrimidine targets with high affinity.
| Autores: | , |
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| Formato: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2010 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/125141 |
| Acesso em linha: | http://hdl.handle.net/10261/125141 |
| Access Level: | acceso abierto |
| Palavra-chave: | Nucleic Acid Conformation Oligonucleotides DNA Nucleic Acid Denaturation Nucleotide sequence |
| Resumo: | DNA Parallel clamps with a polypurine strand linked to a polypyrimidine Hoogsteen strand containing locked nucleic acids bind their corresponding polypyrimidine targets with high affinity. |
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