Replication Data for: Positive impact of a faecal-based screening programme on colorectal cancer mortality risk
Retrospective cohort that included invitees aged 50-69 years of a CRC screening program (target population of 85,000 people) in Catalonia (Spain) from 2000-2015 with mortality follow-up until 2020. Screen-detected CRC was a cancer diagnosed after a positive faecal occult blood test (guaiac or immuno...
| Autores: | , , , , , , |
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| Tipo de recurso: | conjunto de datos |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Consorci de Serveis Universitaris de Catalunya (CSUC) |
| Repositorio: | CORA.Repositori de Dades de Recerca |
| OAI Identifier: | oai:dnet:cora.rdr____::de8e43678243d018b0d2702d6802f8f8 |
| Acceso en línea: | https://doi.org/10.34810/DATA119 |
| Access Level: | acceso abierto |
| Palabra clave: | Medicine, Health and Life Sciences population-based screening colorectal cancer mortality |
| Sumario: | Retrospective cohort that included invitees aged 50-69 years of a CRC screening program (target population of 85,000 people) in Catalonia (Spain) from 2000-2015 with mortality follow-up until 2020. Screen-detected CRC was a cancer diagnosed after a positive faecal occult blood test (guaiac or immunochemical); interval cancer was a cancer diagnosed after a negative test result and before the next invitation to the program (≤24 months); non-uptake cancer was a cancer in subjects who declined screening. A total of 624 people were diagnosed with CRC (n = 265 screen-detected, n = 103 interval cancers, n = 256 non-uptake). In the multivariate analysis, we observed a 74% increase in mortality rate in the group with interval CRC compared to screen-detected CRC adjusted for age, sex, location and stage (HR: 1.74%, 95% CI:1.08-2.82, P = 0.02). These differences were found even when we restricted for advanced-cancers participants. In the stratified analysis for type of faecal occult blood test, a lower mortality rate was only observed among FIT screen-detected CRCs. |
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