Trends in HIV testing, prevalence among first-time testers, and incidence in most-at-risk populations in Spain: the EPI-VIH Study, 2000 to 2009

During 2000 to 2009, data on people undergoing HIV testing and on those newly diagnosed with HIV were collected in a network of 20 Spanish clinics specialising in sexually transmitted infections and/or HIV testing and counselling. The number of tests performed, overall and disaggregated by different...

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Detalles Bibliográficos
Autores: Bleda, Maria Jose, Varela, J R, Ordonana, J, Azpiri, M A, Vall, M, Santos, C, Viloria, L, de Armas, C, Ureña, José Manuel, Trullen, J, Pueyo, I, Martinez, B, Puerta, T, Vera, M, Sanz, I, Junquera, M L, Landa, M C, Martinez, E, Camara, M M, Belda, J, Bru, F J, Diez Ruiz-Navarro, Mercedes, Diaz Franco, Asuncion
Tipo de recurso: artículo
Fecha de publicación:2014
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/10288
Acceso en línea:http://hdl.handle.net/20.500.12105/10288
Access Level:acceso abierto
Palabra clave:AIDS Serodiagnosis
Adolescent
Adult
Antiretroviral Therapy, Highly Active
Cohort Studies
Female
HIV Infections
HIV Seroprevalence
Heterosexuality
Homosexuality, Male
Humans
Incidence
Logistic Models
Male
Middle Aged
Prevalence
Sex Workers
Sexual Behavior
Sexually Transmitted Diseases
Spain
Substance Abuse, Intravenous
Transgender Persons
Vulnerable Populations
Young Adult
Descripción
Sumario:During 2000 to 2009, data on people undergoing HIV testing and on those newly diagnosed with HIV were collected in a network of 20 Spanish clinics specialising in sexually transmitted infections and/or HIV testing and counselling. The number of tests performed, overall and disaggregated by different variables, was obtained. HIV prevalence among first-time testers and HIV incidence among repeat testers were calculated. To evaluate trends, joinpoint regression models were fitted. In total, 236,939 HIV tests were performed for 165,745 individuals. Overall HIV prevalence among persons seeking HIV testing was 2.5% (95% CI: 2.4 to 2.6). Prevalence was highest in male sex workers who had sex with other men (19.0% (95% CI: 16.7 to 21.4)) and was lowest in female sex workers (0.8% (95% CI: 0.7 to 0.9)). Significant trends in prevalence were observed in men who have sex with men (MSM) (increasing) and heterosexual individuals (decreasing). The incidence analysis included 30,679 persons, 64,104 person-years (py) of follow-up and 642 seroconversions. The overall incidence rate (IR) was 1.0/100 py (95% CI: 0.9/100 to 1.1/100). Incidence was significantly higher in men and transgender females than in women (1.8/100 py (95% CI: 1.6 to 1.9), 1.2/100 py (95% CI: 0.5 to 2.8) and 0.1/100 py (95% CI: 0.09 to 0.2) respectively) and increased with age until 35–39 years. IRs in MSM and people who inject drugs were significantly greater than in heterosexual individuals (2.5/100 py (95% CI: 2.3 to 2.7), 1.6/100 py (95% CI: 1.1 to 2.2) and 0.1/100 py (95% CI: 0.09 to 0.2) respectively), and an upward trend was observed in MSM. Our results call for HIV prevention to be reinforced in MSM and transgender women in Spain.

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