The management of heart failure cardiogenic shock

Background: Observational data suggest that the subset of patients with heart failure related CS (HF-CS) now predominate critical care admissions for CS. There are no dedicated HF-CS randomised control trials completed to date which reliably inform clinical practice or clinical guidelines. We sought...

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Detalles Bibliográficos
Autores: Williams, Stefan, Kalakoutas, Antonis|||0000-0001-8184-6152, Olusanya, Segun, Schrage, Benedict, Tavazzi, Guido|||0000-0002-9560-5138, Carnicelli, Anthony P., Montero, Santiago|||0000-0002-0984-3472, Vandenbriele, Christophe, Luk, Adriana, Lim, Hoong Sern|||0000-0002-6569-1805, Bhagra, Sai Kiran|||0000-0001-8606-2904, Ott, Sascha|||0000-0003-1475-2046, Farrero, Marta|||0000-0002-2404-8821, Samsky, Marc D., Kennedy, Jamie L.W., Sen, Sounok, Agrawal, Richa, Rampersad, Penelope|||0000-0003-4829-9059, Coniglio, Amanda, Pappalardo, Federico, Barnett, Christopher, Proudfoot, Alastair G.
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:301889
Acceso en línea:https://ddd.uab.cat/record/301889
https://dx.doi.org/urn:doi:10.1186/s13054-024-04884-5
Access Level:acceso abierto
Descripción
Sumario:Background: Observational data suggest that the subset of patients with heart failure related CS (HF-CS) now predominate critical care admissions for CS. There are no dedicated HF-CS randomised control trials completed to date which reliably inform clinical practice or clinical guidelines. We sought to identify aspects of HF-CS care where both consensus and uncertainty may exist to guide clinical practice and future clinical trial design, with a specific focus on HF-CS due to acute decompensated chronic HF. Methods: A 16-person multi-disciplinary panel comprising of international experts was assembled. A modified RAND/University of California, Los Angeles, appropriateness methodology was used. A survey comprising of 34 statements was completed. Participants anonymously rated the appropriateness of each statement on a scale of 1 to 9 (1-3 as inappropriate, 4-6 as uncertain and as 7-9 appropriate). Results: Of the 34 statements, 20 were rated as appropriate and 14 were rated as inappropriate. Uncertainty existed across all three domains: the initial assessment and management of HF-CS; escalation to temporary Mechanical Circulatory Support (tMCS); and weaning from tMCS in HF-CS. Significant disagreement between experts (deemed present when the disagreement index exceeded 1) was only identified when deliberating the utility of thoracic ultrasound in the immediate management of HF-CS. Conclusion: This study has highlighted several areas of practice where large-scale prospective registries and clinical trials in the HF-CS population are urgently needed to reliably inform clinical practice and the synthesis of future societal HF-CS guidelines. (Figure presented.).