Association between classes and subclasses of polyphenol intake and 5‐year body weight changes in the EPIC‐PANACEA study

Objective: The aim of this study was to evaluate the associations among the intake of total polyphenols, polyphenol classes, and polyphenol subclasses and body weight change over 5years. Methods: A total of 349,165 men and women aged 25 to 70years were recruited in the Physical Activity, Nutrition,...

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Detalles Bibliográficos
Autores: Castañeda, Jazmin, Gil Lespinard, Mercedes, Almanza Aguilera, Enrique, Llaha, Fjorida, Gómez, Jesús Humberto, Bondonno, Nicola, Tjønneland, Anne, Overvad, Kim, Katzke, Verena, Schulze, Matthias B., Masala, Giovanna, Agnoli, Claudia, Santucci de Magistris, Maria, Tumino, Rosario, Sacerdote, Carlotta, Skeie, Guri, Brustad, Magritt, Lasheras, Cristina, Molina Montes, Esther, Chirlaque, María Dolores, Barricarte, Aurelio, Sonestedt, Emily, Silva, Marisa Da, Johansson, Ingegerd, Hultdin, Johan, May, Anne M., Forouhi, Nita G., Heath, Alicia K., Freisling, Heinz, Weiderpass, Elisabete, Scalbert, Augustin, Zamora Ros, Raul
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/205283
Acceso en línea:https://hdl.handle.net/2445/205283
Access Level:acceso abierto
Palabra clave:Polifenols
Obesitat
Polyphenols
Obesity
Descripción
Sumario:Objective: The aim of this study was to evaluate the associations among the intake of total polyphenols, polyphenol classes, and polyphenol subclasses and body weight change over 5years. Methods: A total of 349,165 men and women aged 25 to 70years were recruited in the Physical Activity, Nutrition, Alcohol, Cessation of Smoking, Eating Out of Home and Obesity (PANACEA) project of the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort from nine European countries. Body weight was measured at baseline and at follow-up after a median time of 5years. Polyphenol intake, including four main polyphenol classes and eighteen subclasses, was estimated using validated dietary questionnaires and Phenol-Explorer. Multilevel mixed linear regression models were used to estimate the associations. Results: Participants gained, on average, 2.6 kg (5.0 kg) over 5years. Total flavonoids intake was inversely associated with body weight change (-0.195kg/5 years, 95% CI: -0.262 to -0.128). However, the intake of total polyphenols (0.205kg/5 years, 95% CI: 0.138 to 0.272) and intake of hydroxycinnamic acids (0.324kg/5 years, 95% CI: 0.267 to 0.381) were positively associated with body weight gain. In analyses stratified by coffee consumption, hydroxycinnamic acid intake was positively associated with body weight gain in coffee consumers (0.379kg/5 years, 95% CI: 0.319 to 0.440), but not in coffee nonconsumers (-0.179kg/5 years, 95% CI: -0.490 to 0.133). Conclusions: Higher intakes of flavonoids and their subclasses are inversely associated with a modest body weight change. Results regarding hydroxycinnamic acids in coffee consumers require further investigation.

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