Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia

Background: The effect of fluid thickening in older patients with oropharyngeal dysphagia (OD) is not settled in the case of mild OD or OD caused by structural abnormalities. Objective: To assess the therapeutic effect and mechanism of action of the xanthan-gum-based thickener Tsururinko Quickly in...

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Autores: Muchová, Johana|||0000-0003-1683-5144, Bolivar-Prados, Mireia|||0000-0002-8896-1150, Nuñez Lara, Adrian, Tomsen, Noemí|||0000-0001-7149-7948, Clavé i Civit, Pere|||0000-0002-0696-8560
Tipo de recurso: artículo
Fecha de publicación:2026
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:dnet:uabarcelona_::980a2cbd0afea7a5a9afc8ba1eb239d2
Acceso en línea:https://ddd.uab.cat/record/328039
https://dx.doi.org/urn:doi:10.3390/nu18071138
Access Level:acceso abierto
Palabra clave:Structural dysphagia
Mild dysphagia
Thickening product
Swallowing safety
Swallowing efficacy
Shear viscosity
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spelling Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal DysphagiaMuchová, Johana|||0000-0003-1683-5144Bolivar-Prados, Mireia|||0000-0002-8896-1150Nuñez Lara, AdrianTomsen, Noemí|||0000-0001-7149-7948Clavé i Civit, Pere|||0000-0002-0696-8560Structural dysphagiaMild dysphagiaThickening productSwallowing safetySwallowing efficacyShear viscosityBackground: The effect of fluid thickening in older patients with oropharyngeal dysphagia (OD) is not settled in the case of mild OD or OD caused by structural abnormalities. Objective: To assess the therapeutic effect and mechanism of action of the xanthan-gum-based thickener Tsururinko Quickly in older patients with structural OD and those with mild OD (Penetration-Aspiration Score < 3). Patients and Methods: We included 25 participants in each group (81.8 ± 7.1 vs. 77.4 ± 7.2 yr, respectively). Participants underwent videofluoroscopy (VFS) while swallowing 10 mL boluses at <50 mPa·s, 100, 200, 400, 800, and 1600 mPa·s to evaluate the safety and efficacy of swallowing and the biomechanics of the swallowing response at each viscosity level. After 30 s oral incubation, the effect of salivary α-amylase on shear viscosity was assessed using viscometer measurements. Results: (a) For the <50 mPa·s liquid series, no aspirations occurred in either group; however, 44% of patients with structural OD and 30% of patients with mild OD showed PAS 2 penetrations. (b) Fluid thickening reduced prevalence of penetrations with a maximal effect at 800 mPa·s and without affecting oral or pharyngeal residue in either group. (c) Increasing shear viscosity did not affect timing of airway protection mechanisms nor bolus kinematics. (d) Oral incubation decreased viscosity by 1.7-1.8% at 800 mPa·s. Conclusions: Fluid thickening with TQ enhances swallowing safety in older patients with structural causes of OD and those with mild OD through compensatory mechanisms and without a consistent increase in pharyngeal residue across the tested viscosity range. 22026-01-0120262026-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/328039https://dx.doi.org/urn:doi:10.3390/nu18071138reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengInstituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI18/00241Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI22/01101open accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:dnet:uabarcelona_::980a2cbd0afea7a5a9afc8ba1eb239d22026-06-06T12:50:31Z
dc.title.none.fl_str_mv Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
title Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
spellingShingle Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
Muchová, Johana|||0000-0003-1683-5144
Structural dysphagia
Mild dysphagia
Thickening product
Swallowing safety
Swallowing efficacy
Shear viscosity
title_short Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
title_full Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
title_fullStr Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
title_full_unstemmed Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
title_sort Effect of Fluid Thickening with a Gum-Based Thickening Product in Older Patients with Structural or Mild Oropharyngeal Dysphagia
dc.creator.none.fl_str_mv Muchová, Johana|||0000-0003-1683-5144
Bolivar-Prados, Mireia|||0000-0002-8896-1150
Nuñez Lara, Adrian
Tomsen, Noemí|||0000-0001-7149-7948
Clavé i Civit, Pere|||0000-0002-0696-8560
author Muchová, Johana|||0000-0003-1683-5144
author_facet Muchová, Johana|||0000-0003-1683-5144
Bolivar-Prados, Mireia|||0000-0002-8896-1150
Nuñez Lara, Adrian
Tomsen, Noemí|||0000-0001-7149-7948
Clavé i Civit, Pere|||0000-0002-0696-8560
author_role author
author2 Bolivar-Prados, Mireia|||0000-0002-8896-1150
Nuñez Lara, Adrian
Tomsen, Noemí|||0000-0001-7149-7948
Clavé i Civit, Pere|||0000-0002-0696-8560
author2_role author
author
author
author
dc.subject.none.fl_str_mv Structural dysphagia
Mild dysphagia
Thickening product
Swallowing safety
Swallowing efficacy
Shear viscosity
topic Structural dysphagia
Mild dysphagia
Thickening product
Swallowing safety
Swallowing efficacy
Shear viscosity
description Background: The effect of fluid thickening in older patients with oropharyngeal dysphagia (OD) is not settled in the case of mild OD or OD caused by structural abnormalities. Objective: To assess the therapeutic effect and mechanism of action of the xanthan-gum-based thickener Tsururinko Quickly in older patients with structural OD and those with mild OD (Penetration-Aspiration Score < 3). Patients and Methods: We included 25 participants in each group (81.8 ± 7.1 vs. 77.4 ± 7.2 yr, respectively). Participants underwent videofluoroscopy (VFS) while swallowing 10 mL boluses at <50 mPa·s, 100, 200, 400, 800, and 1600 mPa·s to evaluate the safety and efficacy of swallowing and the biomechanics of the swallowing response at each viscosity level. After 30 s oral incubation, the effect of salivary α-amylase on shear viscosity was assessed using viscometer measurements. Results: (a) For the <50 mPa·s liquid series, no aspirations occurred in either group; however, 44% of patients with structural OD and 30% of patients with mild OD showed PAS 2 penetrations. (b) Fluid thickening reduced prevalence of penetrations with a maximal effect at 800 mPa·s and without affecting oral or pharyngeal residue in either group. (c) Increasing shear viscosity did not affect timing of airway protection mechanisms nor bolus kinematics. (d) Oral incubation decreased viscosity by 1.7-1.8% at 800 mPa·s. Conclusions: Fluid thickening with TQ enhances swallowing safety in older patients with structural causes of OD and those with mild OD through compensatory mechanisms and without a consistent increase in pharyngeal residue across the tested viscosity range.
publishDate 2026
dc.date.none.fl_str_mv 2
2026-01-01
2026
2026-01-01
dc.type.none.fl_str_mv Article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://ddd.uab.cat/record/328039
https://dx.doi.org/urn:doi:10.3390/nu18071138
url https://ddd.uab.cat/record/328039
https://dx.doi.org/urn:doi:10.3390/nu18071138
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI18/00241
Instituto de Salud Carlos III https://doi.org/10.13039/501100004587 PI22/01101
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Dipòsit Digital de Documents de la UAB
instname:Universitat Autònoma de Barcelona
instname_str Universitat Autònoma de Barcelona
reponame_str Dipòsit Digital de Documents de la UAB
collection Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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