Biodegradable Polycarbonate Iongels for Electrophysiology Measurements
In recent years, gels based on ionic liquids incorporated into polymer matrices, namely iongels, have emerged as long-term contact media for cutaneous electrophysiology. Iongels possess high ionic conductivity and negligible vapor pressure and can be designed on demand. In spite of the extensive eff...
| Autores: | , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universidad del País Vasco |
| Repositorio: | Addi. Archivo Digital para la Docencia y la Investigación |
| OAI Identifier: | oai:addi.ehu.eus:10810/31827 |
| Acceso en línea: | http://hdl.handle.net/10810/31827 |
| Access Level: | acceso abierto |
| Palabra clave: | iongels polycarbonate electrophysiology electrodes biodegradable 8-membered cyclic carbonates dry electrodes electroencephalography polymerization recordings hydrogels |
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Biodegradable Polycarbonate Iongels for Electrophysiology MeasurementsYuen, AlexanderPorcarelli, LucaHernández Aguirresarobe, RobertoSánchez Sánchez, AnaDel Agua López, IsabelIsmailov, UseinMalliaras, George G.Mecerreyes Molero, DavidIsmailova, EsmaSardon Muguruza, Haritziongelspolycarbonateelectrophysiologyelectrodesbiodegradable8-membered cyclic carbonatesdry electrodeselectroencephalographypolymerizationrecordingshydrogelsIn recent years, gels based on ionic liquids incorporated into polymer matrices, namely iongels, have emerged as long-term contact media for cutaneous electrophysiology. Iongels possess high ionic conductivity and negligible vapor pressure and can be designed on demand. In spite of the extensive efforts devoted to the preparation of biodegradable ionic liquids, the investigations related to the preparation of iongels based on biodegradable polymers remain scarce. In this work, biodegradable polycarbonate-based iongels are prepared by ring-opening polymerization of N-substituted eight ring membered cyclic carbonate monomers in the presence of imidazolium lactate ionic liquid. Our iongels are able to take up 10-30 wt % of ionic liquid and become softer materials by increasing the amount of free ionic liquid. Rheological measurements showed that the cross-over point between the storage modulus G' and loss modulus G '' occurs at lower angular frequencies when the loading of free ionic liquid increases. These gels are able to take up to 30 wt % of the ionic liquid and the ionic conductivity of these gels increased up to 5 x 10(-4) S.cm(-1) at 25 degrees C as the amount of free ionic liquid increased. Additionally, we assess the biodegradation studies of the iongels by immersing them in water. The iongels decrease the impedance with the human skin to levels that are similar to commercial Ag/AgCl electrodes, allowing an accurate physiologic signals recording. The low toxicity and biodegradability of polycarbonate-based iongels make these materials highly attractive for cutaneous electrophysiology applications.The authors would like to thank the European Commission for its financial support through the projects of OrgBIO-ITN 607896. A. Sanchez-Sanchez is thankful for the Marie Curie IF BIKE Project No. 742865.MDPI201920192018info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/31827reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoIngléshttps://www.mdpi.com/2073-4360/10/9/989info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/es/This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).Atribución 3.0 Españaoai:addi.ehu.eus:10810/318272026-06-18T09:23:17Z |
| dc.title.none.fl_str_mv |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| title |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| spellingShingle |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements Yuen, Alexander iongels polycarbonate electrophysiology electrodes biodegradable 8-membered cyclic carbonates dry electrodes electroencephalography polymerization recordings hydrogels |
| title_short |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| title_full |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| title_fullStr |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| title_full_unstemmed |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| title_sort |
Biodegradable Polycarbonate Iongels for Electrophysiology Measurements |
| dc.creator.none.fl_str_mv |
Yuen, Alexander Porcarelli, Luca Hernández Aguirresarobe, Roberto Sánchez Sánchez, Ana Del Agua López, Isabel Ismailov, Usein Malliaras, George G. Mecerreyes Molero, David Ismailova, Esma Sardon Muguruza, Haritz |
| author |
Yuen, Alexander |
| author_facet |
Yuen, Alexander Porcarelli, Luca Hernández Aguirresarobe, Roberto Sánchez Sánchez, Ana Del Agua López, Isabel Ismailov, Usein Malliaras, George G. Mecerreyes Molero, David Ismailova, Esma Sardon Muguruza, Haritz |
| author_role |
author |
| author2 |
Porcarelli, Luca Hernández Aguirresarobe, Roberto Sánchez Sánchez, Ana Del Agua López, Isabel Ismailov, Usein Malliaras, George G. Mecerreyes Molero, David Ismailova, Esma Sardon Muguruza, Haritz |
| author2_role |
author author author author author author author author author |
| dc.subject.none.fl_str_mv |
iongels polycarbonate electrophysiology electrodes biodegradable 8-membered cyclic carbonates dry electrodes electroencephalography polymerization recordings hydrogels |
| topic |
iongels polycarbonate electrophysiology electrodes biodegradable 8-membered cyclic carbonates dry electrodes electroencephalography polymerization recordings hydrogels |
| description |
In recent years, gels based on ionic liquids incorporated into polymer matrices, namely iongels, have emerged as long-term contact media for cutaneous electrophysiology. Iongels possess high ionic conductivity and negligible vapor pressure and can be designed on demand. In spite of the extensive efforts devoted to the preparation of biodegradable ionic liquids, the investigations related to the preparation of iongels based on biodegradable polymers remain scarce. In this work, biodegradable polycarbonate-based iongels are prepared by ring-opening polymerization of N-substituted eight ring membered cyclic carbonate monomers in the presence of imidazolium lactate ionic liquid. Our iongels are able to take up 10-30 wt % of ionic liquid and become softer materials by increasing the amount of free ionic liquid. Rheological measurements showed that the cross-over point between the storage modulus G' and loss modulus G '' occurs at lower angular frequencies when the loading of free ionic liquid increases. These gels are able to take up to 30 wt % of the ionic liquid and the ionic conductivity of these gels increased up to 5 x 10(-4) S.cm(-1) at 25 degrees C as the amount of free ionic liquid increased. Additionally, we assess the biodegradation studies of the iongels by immersing them in water. The iongels decrease the impedance with the human skin to levels that are similar to commercial Ag/AgCl electrodes, allowing an accurate physiologic signals recording. The low toxicity and biodegradability of polycarbonate-based iongels make these materials highly attractive for cutaneous electrophysiology applications. |
| publishDate |
2018 |
| dc.date.none.fl_str_mv |
2018 2019 2019 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10810/31827 |
| url |
http://hdl.handle.net/10810/31827 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
https://www.mdpi.com/2073-4360/10/9/989 |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/3.0/es/ Atribución 3.0 España |
| eu_rights_str_mv |
openAccess |
| rights_invalid_str_mv |
http://creativecommons.org/licenses/by/3.0/es/ Atribución 3.0 España |
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application/pdf |
| dc.publisher.none.fl_str_mv |
MDPI |
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MDPI |
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reponame:Addi. Archivo Digital para la Docencia y la Investigación instname:Universidad del País Vasco |
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Addi. Archivo Digital para la Docencia y la Investigación |
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Addi. Archivo Digital para la Docencia y la Investigación |
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