Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey

Sex differences; Valvular heart disease

Detalles Bibliográficos
Autores: Mascherbauer, Julia, Kammerlander, Andreas, Nitsche, Christian, Bax, Jeroen, delgado, victoria, Evangelista Masip, Arturo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Departament de Salut de la Generalitat de Catalunya (DS)
Repositorio:Scientia. Dipòsit d'Informació Digital del Departament de Salut
OAI Identifier:oai:scientiasalut.gencat.cat:11351/12615
Acceso en línea:https://hdl.handle.net/11351/12615
Access Level:acceso abierto
Palabra clave:Cor - Vàlvules - Malalties
Cor - Malalties - Factors sexuals
DISEASES::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacas
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
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oai_identifier_str oai:scientiasalut.gencat.cat:11351/12615
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
title Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
spellingShingle Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
Mascherbauer, Julia
Cor - Vàlvules - Malalties
Cor - Malalties - Factors sexuals
DISEASES::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacas
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
title_short Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
title_full Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
title_fullStr Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
title_full_unstemmed Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
title_sort Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey
dc.creator.none.fl_str_mv Mascherbauer, Julia
Kammerlander, Andreas
Nitsche, Christian
Bax, Jeroen
delgado, victoria
Evangelista Masip, Arturo
author Mascherbauer, Julia
author_facet Mascherbauer, Julia
Kammerlander, Andreas
Nitsche, Christian
Bax, Jeroen
delgado, victoria
Evangelista Masip, Arturo
author_role author
author2 Kammerlander, Andreas
Nitsche, Christian
Bax, Jeroen
delgado, victoria
Evangelista Masip, Arturo
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Institut Català de la Salut
[Mascherbauer J] Department of Internal Medicine 3, University Hospital St. Pölten, St. Poelten, Karl Landsteiner University of Health Sciences, Krems, Austria. [Kammerlander A, Nitsche C] Department of Internal Medicine 2, Division of Cardiology, Medical University of Vienna, Vienna, Austria. [Bax J] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. [Delgado V] Heart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain. [Evangelista A] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain
Vall d'Hebron Barcelona Hospital Campus
dc.subject.none.fl_str_mv Cor - Vàlvules - Malalties
Cor - Malalties - Factors sexuals
DISEASES::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacas
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
topic Cor - Vàlvules - Malalties
Cor - Malalties - Factors sexuals
DISEASES::Cardiovascular Diseases::Heart Diseases::Heart Valve Diseases
HEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex Factors
ENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacas
ATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexuales
description Sex differences; Valvular heart disease
publishDate 2024
dc.date.none.fl_str_mv 2024
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/11351/12615
url https://hdl.handle.net/11351/12615
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv European Heart Journal;45(37)
https://doi.org/10.1093/eurheartj/ehae523
dc.rights.none.fl_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv Scientia
reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut
instname:Departament de Salut de la Generalitat de Catalunya (DS)
instname_str Departament de Salut de la Generalitat de Catalunya (DS)
reponame_str Scientia. Dipòsit d'Informació Digital del Departament de Salut
collection Scientia. Dipòsit d'Informació Digital del Departament de Salut
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869425491498237952
spelling Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II surveyMascherbauer, JuliaKammerlander, AndreasNitsche, ChristianBax, Jeroendelgado, victoriaEvangelista Masip, ArturoCor - Vàlvules - MalaltiesCor - Malalties - Factors sexualsDISEASES::Cardiovascular Diseases::Heart Diseases::Heart Valve DiseasesHEALTH CARE::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Sex FactorsENFERMEDADES::enfermedades cardiovasculares::enfermedades cardíacas::enfermedades de las válvulas cardíacasATENCIÓN DE SALUD::calidad, acceso y evaluación de la atención sanitaria::calidad de la atención sanitaria::factores epidemiológicos::factores sexualesSex differences; Valvular heart diseaseDiferencias de sexo; Enfermedad cardíaca valvulardiferències de sexe; Malaltia cardíaca valvularBackground and aims: To assess sex differences in disease characteristics and treatment of patients with severe native valvular heart disease (VHD) included in the VHD II EURObservational Research Programme. Methods: A total of 5219 patients were enrolled in 208 European and North African centres and followed for 6 months [41.2% aortic stenosis (AS), 5.3% aortic regurgitation (AR), 4.5% mitral stenosis (MS), 21.3% mitral regurgitation (MR), 2.7% isolated right-sided VHD, 24.9% multiple left-sided VHD]. Indications for intervention were considered concordant if corresponding to class I recommendations specified in the 2012 ESC or 2014 AHA/ACC VHD guidelines. Results: Overall, women were older, more symptomatic, and presented with a higher EuroSCORE II. Bicuspid aortic valve and AR were more prevalent among men while mitral disease, concomitant tricuspid regurgitation (TR), and AS above age 65 were more prevalent among women. On multivariable regression analysis, concordance with recommended treatment was significantly poorer in women with MS and primary MR (both P < .001). Age, patient refusal, and decline of symptoms after conservative treatment were reported significantly more often as reasons to withhold the intervention in females. Concomitant tricuspid intervention was performed at a similar rate in both sexes although prevalence of significant TR was significantly higher in women. In-hospital and 6-month survival did not differ between sexes. Conclusions: (i) Valvular heart disease subtype varied between sexes; (ii) concordance with recommended intervention for MS and primary MR was significantly lower for women; and (iii) survival of men and women was similar at 6 months.Since the start of EORP, the following companies have supported the programme: Abbott Vascular (2011–21), Amgen (2009–18), AstraZeneca (2014–21), Bayer AG (2009–18), Boehringer Ingelheim (2009–19), Boston Scientific (2009–12), Bristol-Myers Squibb, Pfizer (2011–19), Daiichi Sankyo Europe (2011–20) and Eli Lilly and Company (2014–17), Edwards (2016–19), Gedeon Richter Plc.Oxford University PressInstitut Català de la Salut[Mascherbauer J] Department of Internal Medicine 3, University Hospital St. Pölten, St. Poelten, Karl Landsteiner University of Health Sciences, Krems, Austria. [Kammerlander A, Nitsche C] Department of Internal Medicine 2, Division of Cardiology, Medical University of Vienna, Vienna, Austria. [Bax J] Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands. [Delgado V] Heart Institute, Germans Trias i Pujol University Hospital, Badalona, Spain. [Evangelista A] Servei de Cardiologia, Vall d’Hebron Hospital Universitari, Barcelona, SpainVall d'Hebron Barcelona Hospital Campus202520252024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/12615Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésEuropean Heart Journal;45(37)https://doi.org/10.1093/eurheartj/ehae523Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/126152026-06-12T09:38:37Z
score 15,81155

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