BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling

Plastid-to-nucleus retrograde signalling (RS) initiated by dysfunctional chloroplasts impact photomorphogenic development. We have previously shown that the transcription factor GLK1 acts downstream of the RS regulator GUN1 in photodamaging conditions to regulate not only the well established expres...

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Authors: Veciana, Nil, Martín, Guiomar, Leivar, Pablo, Monte, Elena
Format: article
Publication Date:2022
Country:España
Institution:Universitat Ramon Llull (URL)
Repository:DAU Arxiu Digital de la Universitat Ramon Llull
OAI Identifier:oai:dau.url.edu:20.500.14342/4439
Online Access:http://hdl.handle.net/20.500.14342/4439
https://doi.org/10.1111/nph.17975
Access Level:Open access
Keyword:B-box factor BBX16
Chloroplastintegrity and retrograde signalling
Cotyledonopening
GLK1
GUN1
Light signalling
Photomorphogenesis
Photoprotection
Plantes--Fotomorfogènesi
577
58
id ES_fcb4d9c6fc4b5aa1028d82eddd3e1148
oai_identifier_str oai:dau.url.edu:20.500.14342/4439
network_acronym_str ES
network_name_str España
repository_id_str
spelling BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signallingVeciana, NilMartín, GuiomarLeivar, PabloMonte, ElenaB-box factor BBX16Chloroplastintegrity and retrograde signallingCotyledonopeningGLK1GUN1Light signallingPhotomorphogenesisPhotoprotectionPlantes--Fotomorfogènesi57758Plastid-to-nucleus retrograde signalling (RS) initiated by dysfunctional chloroplasts impact photomorphogenic development. We have previously shown that the transcription factor GLK1 acts downstream of the RS regulator GUN1 in photodamaging conditions to regulate not only the well established expression of photosynthesis-associated nuclear genes (PhANGs) but also to regulate seedling morphogenesis. Specifically, the GUN1/GLK1 module inhibits the light-induced phytochrome-interacting factor (PIF)-repressed transcriptional network to suppress cotyledon development when chloroplast integrity is compromised, modulating the area exposed to potentially damaging high light. However, how the GUN1/GLK1 module inhibits photomorphogenesis upon chloroplast damage remained undefined. Here, we report the identification of BBX16 as a novel direct target of GLK1. BBX16 is induced and promotes photomorphogenesis in moderate light and is repressed via GUN1/GLK1 after chloroplast damage. Additionally, we showed that BBX16 represents a regulatory branching point downstream of GUN1/GLK1 in the regulation of PhANG expression and seedling development upon RS activation. The gun1 phenotype in lincomycin and the gun1-like phenotype of GLK1OX are markedly suppressed in gun1bbx16 and GLK1OXbbx16. This study identified BBX16 as the first member of the BBX family involved in RS, and defines a molecular bifurcation mechanism operated by GLK1/BBX16 to optimise seedling de-etiolation, and to ensure photoprotection in unfavourable light conditions.info:eu-repo/semantics/publishedVersionWileyUniversitat Ramon Llull. IQS202420242022info:eu-repo/semantics/articlep.14application/pdfhttp://hdl.handle.net/20.500.14342/4439https://doi.org/10.1111/nph.17975reponame:DAU Arxiu Digital de la Universitat Ramon Llullinstname:Universitat Ramon Llull (URL)InglésNew Phytologist 2022, 234(1), 93-106info:eu-repo/grantAgreement/MINECO/Severo Ochoa Programme for Centers of Excellence in R&D/SEV-2015-0533info:eu-repo/grantAgreement/MINECO i FEDER/PN I+D/BIO2015-68460-Pinfo:eu-repo/grantAgreement/MCI i FEDER/PN I+D/PGC2018-099987-B-I00info:eu-repo/grantAgreement/SUR del DEC/SGR/2017SGR-718© L'autor/aAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:dau.url.edu:20.500.14342/44392026-06-21T06:40:37Z
dc.title.none.fl_str_mv BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
title BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
spellingShingle BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
Veciana, Nil
B-box factor BBX16
Chloroplastintegrity and retrograde signalling
Cotyledonopening
GLK1
GUN1
Light signalling
Photomorphogenesis
Photoprotection
Plantes--Fotomorfogènesi
577
58
title_short BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
title_full BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
title_fullStr BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
title_full_unstemmed BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
title_sort BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1/GLK1 module during retrograde signalling
dc.creator.none.fl_str_mv Veciana, Nil
Martín, Guiomar
Leivar, Pablo
Monte, Elena
author Veciana, Nil
author_facet Veciana, Nil
Martín, Guiomar
Leivar, Pablo
Monte, Elena
author_role author
author2 Martín, Guiomar
Leivar, Pablo
Monte, Elena
author2_role author
author
author
dc.contributor.none.fl_str_mv Universitat Ramon Llull. IQS
dc.subject.none.fl_str_mv B-box factor BBX16
Chloroplastintegrity and retrograde signalling
Cotyledonopening
GLK1
GUN1
Light signalling
Photomorphogenesis
Photoprotection
Plantes--Fotomorfogènesi
577
58
topic B-box factor BBX16
Chloroplastintegrity and retrograde signalling
Cotyledonopening
GLK1
GUN1
Light signalling
Photomorphogenesis
Photoprotection
Plantes--Fotomorfogènesi
577
58
description Plastid-to-nucleus retrograde signalling (RS) initiated by dysfunctional chloroplasts impact photomorphogenic development. We have previously shown that the transcription factor GLK1 acts downstream of the RS regulator GUN1 in photodamaging conditions to regulate not only the well established expression of photosynthesis-associated nuclear genes (PhANGs) but also to regulate seedling morphogenesis. Specifically, the GUN1/GLK1 module inhibits the light-induced phytochrome-interacting factor (PIF)-repressed transcriptional network to suppress cotyledon development when chloroplast integrity is compromised, modulating the area exposed to potentially damaging high light. However, how the GUN1/GLK1 module inhibits photomorphogenesis upon chloroplast damage remained undefined. Here, we report the identification of BBX16 as a novel direct target of GLK1. BBX16 is induced and promotes photomorphogenesis in moderate light and is repressed via GUN1/GLK1 after chloroplast damage. Additionally, we showed that BBX16 represents a regulatory branching point downstream of GUN1/GLK1 in the regulation of PhANG expression and seedling development upon RS activation. The gun1 phenotype in lincomycin and the gun1-like phenotype of GLK1OX are markedly suppressed in gun1bbx16 and GLK1OXbbx16. This study identified BBX16 as the first member of the BBX family involved in RS, and defines a molecular bifurcation mechanism operated by GLK1/BBX16 to optimise seedling de-etiolation, and to ensure photoprotection in unfavourable light conditions.
publishDate 2022
dc.date.none.fl_str_mv 2022
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.14342/4439
https://doi.org/10.1111/nph.17975
url http://hdl.handle.net/20.500.14342/4439
https://doi.org/10.1111/nph.17975
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv New Phytologist 2022, 234(1), 93-106
info:eu-repo/grantAgreement/MINECO/Severo Ochoa Programme for Centers of Excellence in R&D/SEV-2015-0533
info:eu-repo/grantAgreement/MINECO i FEDER/PN I+D/BIO2015-68460-P
info:eu-repo/grantAgreement/MCI i FEDER/PN I+D/PGC2018-099987-B-I00
info:eu-repo/grantAgreement/SUR del DEC/SGR/2017SGR-718
dc.rights.none.fl_str_mv © L'autor/a
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © L'autor/a
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv p.14
application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:DAU Arxiu Digital de la Universitat Ramon Llull
instname:Universitat Ramon Llull (URL)
instname_str Universitat Ramon Llull (URL)
reponame_str DAU Arxiu Digital de la Universitat Ramon Llull
collection DAU Arxiu Digital de la Universitat Ramon Llull
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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