Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study
We evaluated the psychometric properties of the Spanish version of the European Organization for Research and Treatment of Multiple Myeloma (MM) specific quality-of-life (QoL) questionnaire module (QLQ-MY20) in relapsed/refractory MM (RRMM) patients. This was an observational, cross-sectional, multi...
| Autores: | , , , , , , , , , , , , , , , , , , |
|---|---|
| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2023 |
| País: | España |
| Recursos: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositório: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/346960 |
| Acesso em linha: | http://hdl.handle.net/10261/346960 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Multiple myeloma Relapsed/refractory multiple myeloma Quality of life Health‐related quality of life EORTC QLQ-MY20 assessment Burden of the disease |
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Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa studyRosiñol, LauraMontes, CarmenBustamante, GabrielaGarzón, SebastiánGonzález García, María-EstherPérez Persona, ErnestoGonzález-Calle, VerónicaSirvent Auzmendi, MaialenArguiñano, José M.González Montes, YolandaRíos Tamayo, RafaelMiguel Llorente, Dunia dePalomera, LuisSampol, AntoniaCouto, María del CarmenGrande, MartaFernández-Nistal, AlonsoNaves, AndreaOcio, Enrique M.Multiple myelomaRelapsed/refractory multiple myelomaQuality of lifeHealth‐related quality of lifeEORTC QLQ-MY20 assessmentBurden of the diseaseWe evaluated the psychometric properties of the Spanish version of the European Organization for Research and Treatment of Multiple Myeloma (MM) specific quality-of-life (QoL) questionnaire module (QLQ-MY20) in relapsed/refractory MM (RRMM) patients. This was an observational, cross-sectional, multicenter study using EORTC QLQ-C30 and QLQ-MY20 in RRMM patients (ClinicalTrials.gov ID NCT03188536). We assessed the non-response rate, ceiling/floor effects, internal consistency, test-retest reliability, and validity. The study included 276 patients (53.3% males, mean [SD] age of 67.4 [10.5] years). The EORTC QLQ-MY20 showed a low non-response rate, very low ceiling and floor effects, and good internal consistency. The test-retest reliability assessment revealed good temporary stability, the construct validity analysis stated four main factors similar to the ones of the original version, and the criterion validity assessment showed no differences between groups. In conclusion, the Spanish version of EORTC QLQ-MY20 is a reliable and valid tool for assessing QoL in RRMM patients.The study was sponsored and funded by Takeda Farmacéutica España.Peer reviewedTaylor & FrancisTakeda Pharmaceutical CompanyConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2024202420232024info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/346960reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)InglésThe underlying dataset has been published as supplementary material of the article in the publisher platform at 10.1080/10428194.2023.2240922http://dx.doi.org/10.1080/10428194.2023.2240922Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3469602026-05-22T06:33:51Z |
| dc.title.none.fl_str_mv |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| title |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| spellingShingle |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study Rosiñol, Laura Multiple myeloma Relapsed/refractory multiple myeloma Quality of life Health‐related quality of life EORTC QLQ-MY20 assessment Burden of the disease |
| title_short |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| title_full |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| title_fullStr |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| title_full_unstemmed |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| title_sort |
Assessment of the psychometric properties of the Spanish version of EORTC QLQ-MY20 and evaluation of health-related quality of Life outcomes in patients with relapsed and/or refractory multiple myeloma in the real-world setting in Spain: results from the CharisMMa study |
| dc.creator.none.fl_str_mv |
Rosiñol, Laura Montes, Carmen Bustamante, Gabriela Garzón, Sebastián González García, María-Esther Pérez Persona, Ernesto González-Calle, Verónica Sirvent Auzmendi, Maialen Arguiñano, José M. González Montes, Yolanda Ríos Tamayo, Rafael Miguel Llorente, Dunia de Palomera, Luis Sampol, Antonia Couto, María del Carmen Grande, Marta Fernández-Nistal, Alonso Naves, Andrea Ocio, Enrique M. |
| author |
Rosiñol, Laura |
| author_facet |
Rosiñol, Laura Montes, Carmen Bustamante, Gabriela Garzón, Sebastián González García, María-Esther Pérez Persona, Ernesto González-Calle, Verónica Sirvent Auzmendi, Maialen Arguiñano, José M. González Montes, Yolanda Ríos Tamayo, Rafael Miguel Llorente, Dunia de Palomera, Luis Sampol, Antonia Couto, María del Carmen Grande, Marta Fernández-Nistal, Alonso Naves, Andrea Ocio, Enrique M. |
| author_role |
author |
| author2 |
Montes, Carmen Bustamante, Gabriela Garzón, Sebastián González García, María-Esther Pérez Persona, Ernesto González-Calle, Verónica Sirvent Auzmendi, Maialen Arguiñano, José M. González Montes, Yolanda Ríos Tamayo, Rafael Miguel Llorente, Dunia de Palomera, Luis Sampol, Antonia Couto, María del Carmen Grande, Marta Fernández-Nistal, Alonso Naves, Andrea Ocio, Enrique M. |
| author2_role |
author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Takeda Pharmaceutical Company Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
| dc.subject.none.fl_str_mv |
Multiple myeloma Relapsed/refractory multiple myeloma Quality of life Health‐related quality of life EORTC QLQ-MY20 assessment Burden of the disease |
| topic |
Multiple myeloma Relapsed/refractory multiple myeloma Quality of life Health‐related quality of life EORTC QLQ-MY20 assessment Burden of the disease |
| description |
We evaluated the psychometric properties of the Spanish version of the European Organization for Research and Treatment of Multiple Myeloma (MM) specific quality-of-life (QoL) questionnaire module (QLQ-MY20) in relapsed/refractory MM (RRMM) patients. This was an observational, cross-sectional, multicenter study using EORTC QLQ-C30 and QLQ-MY20 in RRMM patients (ClinicalTrials.gov ID NCT03188536). We assessed the non-response rate, ceiling/floor effects, internal consistency, test-retest reliability, and validity. The study included 276 patients (53.3% males, mean [SD] age of 67.4 [10.5] years). The EORTC QLQ-MY20 showed a low non-response rate, very low ceiling and floor effects, and good internal consistency. The test-retest reliability assessment revealed good temporary stability, the construct validity analysis stated four main factors similar to the ones of the original version, and the criterion validity assessment showed no differences between groups. In conclusion, the Spanish version of EORTC QLQ-MY20 is a reliable and valid tool for assessing QoL in RRMM patients. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023 2024 2024 2024 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 Publisher's version info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10261/346960 |
| url |
http://hdl.handle.net/10261/346960 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
The underlying dataset has been published as supplementary material of the article in the publisher platform at 10.1080/10428194.2023.2240922 http://dx.doi.org/10.1080/10428194.2023.2240922 Sí |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
Taylor & Francis |
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Taylor & Francis |
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reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC instname:Consejo Superior de Investigaciones Científicas (CSIC) |
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Consejo Superior de Investigaciones Científicas (CSIC) |
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DIGITAL.CSIC. Repositorio Institucional del CSIC |
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DIGITAL.CSIC. Repositorio Institucional del CSIC |
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