Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization

The electrical impedance of biological samples is known in the literature as Electrical Bioimpedance (EBI). The Electrical Bioimpedance enables to characterize physiological conditions and events that are interesting for physiological research and medical diagnosis. Although the Electrical Bioimpeda...

Descripción completa

Detalles Bibliográficos
Autor: Sánchez Terrones, Benjamín
Tipo de recurso: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2012
País:España
Institución:CBUC, CESCA
Repositorio:TDR. Tesis Doctorales en Red
OAI Identifier:oai:www.tdx.cat:10803/132281
Acceso en línea:http://hdl.handle.net/10803/132281
https://dx.doi.org/10.5821/dissertation-2117-95189
Access Level:acceso abierto
Palabra clave:577
621.3
67
id ES_fc4e7f4cf11089b708bb1e9b8662dbb7
oai_identifier_str oai:www.tdx.cat:10803/132281
network_acronym_str ES
network_name_str España
repository_id_str
dc.title.none.fl_str_mv Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
title Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
spellingShingle Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
Sánchez Terrones, Benjamín
577
621.3
67
title_short Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
title_full Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
title_fullStr Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
title_full_unstemmed Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
title_sort Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterization
dc.creator.none.fl_str_mv Sánchez Terrones, Benjamín
author Sánchez Terrones, Benjamín
author_facet Sánchez Terrones, Benjamín
author_role author
dc.contributor.none.fl_str_mv Bragós Bardia, Ramon
Vandersteen, Gerd
Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica
dc.subject.none.fl_str_mv 577
621.3
67
topic 577
621.3
67
description The electrical impedance of biological samples is known in the literature as Electrical Bioimpedance (EBI). The Electrical Bioimpedance enables to characterize physiological conditions and events that are interesting for physiological research and medical diagnosis. Although the Electrical Bioimpedance weakness is that it depends on many physiological parameters, on the other hand, it is suitable for many medical applications where minimally invasive and real-time measurements with simple and practical implementations are needed. The Electrical Impedance Spectroscopy (EIS) techniques based on broadband excitations are expected to help to understand various unsolved problems in biomedical applications. Broadband EIS opens up the possibility to reduce drastically the measuring time for acquiring EBI time-variations but, at the same time, measuring in a short time compromises the EBI accuracy. The way to overcome this intrinsic loss of accuracy relies on the design of the appropriate time/frequency input excitation properties and the use of the suitable spectral analysis processing techniques. The presented thesis covers the topics related to study of broadband excitations for Impedance Spectroscopy in biomedical applications and, more specific, the influence of the multisine excitation time/frequency properties on the impedance spectrum accuracy and its optimization. Furthermore, an advanced fast signal processing method has been implemented to process in real-time EBI data corrupted by transients, a common situation when measuring in a short measuring time. Despite being the goal to apply all this knowledge for myocardial tissue regeneration monitoring, at the moment of drafting the thesis, any of the research projects that have supported this thesis have issued functional beating tissue. For that reason, the theory presented has been validated by a set of experimental measurements over animals and patients where the impedance spectrum time-varying properties were pretended to be characterized. The thesis presents novel findings of relevance of a successful application of broadband EIS in two different measurement campaigns where it has been put in practice: (1) within the collaboration of the pneumology and cardiology service from Hospital Santa Creu i Sant Pau for in-vivo human lung tissue characterization, and (2), within the measurement of animal healthy myocardium tissue electrical impedance including its dynamic behavior during the cardiac cycle.
publishDate 2012
dc.date.none.fl_str_mv 2012
2014
2014
dc.type.none.fl_str_mv info:eu-repo/semantics/doctoralThesis
info:eu-repo/semantics/publishedVersion
format doctoralThesis
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10803/132281
https://dx.doi.org/10.5821/dissertation-2117-95189
url http://hdl.handle.net/10803/132281
https://dx.doi.org/10.5821/dissertation-2117-95189
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 120 p.
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universitat Politècnica de Catalunya
publisher.none.fl_str_mv Universitat Politècnica de Catalunya
dc.source.none.fl_str_mv TDX (Tesis Doctorals en Xarxa)
reponame:TDR. Tesis Doctorales en Red
instname:CBUC, CESCA
instname_str CBUC, CESCA
reponame_str TDR. Tesis Doctorales en Red
collection TDR. Tesis Doctorales en Red
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869425410153906176
spelling Broadband electrical impedance spectroscopy for dynamic electrical bio-impedance characterizationSánchez Terrones, Benjamín577621.367The electrical impedance of biological samples is known in the literature as Electrical Bioimpedance (EBI). The Electrical Bioimpedance enables to characterize physiological conditions and events that are interesting for physiological research and medical diagnosis. Although the Electrical Bioimpedance weakness is that it depends on many physiological parameters, on the other hand, it is suitable for many medical applications where minimally invasive and real-time measurements with simple and practical implementations are needed. The Electrical Impedance Spectroscopy (EIS) techniques based on broadband excitations are expected to help to understand various unsolved problems in biomedical applications. Broadband EIS opens up the possibility to reduce drastically the measuring time for acquiring EBI time-variations but, at the same time, measuring in a short time compromises the EBI accuracy. The way to overcome this intrinsic loss of accuracy relies on the design of the appropriate time/frequency input excitation properties and the use of the suitable spectral analysis processing techniques. The presented thesis covers the topics related to study of broadband excitations for Impedance Spectroscopy in biomedical applications and, more specific, the influence of the multisine excitation time/frequency properties on the impedance spectrum accuracy and its optimization. Furthermore, an advanced fast signal processing method has been implemented to process in real-time EBI data corrupted by transients, a common situation when measuring in a short measuring time. Despite being the goal to apply all this knowledge for myocardial tissue regeneration monitoring, at the moment of drafting the thesis, any of the research projects that have supported this thesis have issued functional beating tissue. For that reason, the theory presented has been validated by a set of experimental measurements over animals and patients where the impedance spectrum time-varying properties were pretended to be characterized. The thesis presents novel findings of relevance of a successful application of broadband EIS in two different measurement campaigns where it has been put in practice: (1) within the collaboration of the pneumology and cardiology service from Hospital Santa Creu i Sant Pau for in-vivo human lung tissue characterization, and (2), within the measurement of animal healthy myocardium tissue electrical impedance including its dynamic behavior during the cardiac cycle.DOCTORAT EN ENGINYERIA ELECTRÒNICA (Pla 2007)Universitat Politècnica de CatalunyaBragós Bardia, RamonVandersteen, GerdUniversitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica201420142012info:eu-repo/semantics/doctoralThesisinfo:eu-repo/semantics/publishedVersion120 p.application/pdfapplication/pdfhttp://hdl.handle.net/10803/132281https://dx.doi.org/10.5821/dissertation-2117-95189TDX (Tesis Doctorals en Xarxa)reponame:TDR. Tesis Doctorales en Redinstname:CBUC, CESCAInglésADVERTIMENT. L'accés als continguts d'aquesta tesi doctoral i la seva utilització ha de respectar els drets de la persona autora. Pot ser utilitzada per a consulta o estudi personal, així com en activitats o materials d'investigació i docència en els termes establerts a l'art. 32 del Text Refós de la Llei de Propietat Intel·lectual (RDL 1/1996). Per altres utilitzacions es requereix l'autorització prèvia i expressa de la persona autora. En qualsevol cas, en la utilització dels seus continguts caldrà indicar de forma clara el nom i cognoms de la persona autora i el títol de la tesi doctoral. No s'autoritza la seva reproducció o altres formes d'explotació efectuades amb finalitats de lucre ni la seva comunicació pública des d'un lloc aliè al servei TDX. Tampoc s'autoritza la presentació del seu contingut en una finestra o marc aliè a TDX (framing). Aquesta reserva de drets afecta tant als continguts de la tesi com als seus resums i índexs.info:eu-repo/semantics/openAccessoai:www.tdx.cat:10803/1322812026-06-14T12:46:07Z
score 15,300719

Similares en LA Referencia