Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV

Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the gen...

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Detalles Bibliográficos
Autores: Wu, Beilei, Blanchard-Letort, Alexandra, Liu, Yan, Zhou, Guanghe, Wang, Xifeng, Elena, Santiago F.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2011
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/47814
Acceso en línea:http://hdl.handle.net/10261/47814
Access Level:acceso abierto
Palabra clave:Plant RNA viruses
Recombination
Sequences
Phylogenies
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spelling Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAVWu, BeileiBlanchard-Letort, AlexandraLiu, YanZhou, GuangheWang, XifengElena, Santiago F.Plant RNA virusesRecombinationSequencesPhylogeniesBarley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDVPAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.15861024 nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus.This work was supported by the Chinese National Key Basic Research Program (973 program No. 2006CB100203) and by the Chinese Nature Science Foundation grant number 30871622. Work in Vale`ncia was supported by the Spanish Ministry of Science and Innovation grant BFU2009-06993 and by Generalitat Valenciana grant PROMETEO2010/019. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Peer reviewedPublic Library of Science201220122011info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/47814reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglésinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/478142026-05-22T06:33:51Z
dc.title.none.fl_str_mv Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
spellingShingle Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
Wu, Beilei
Plant RNA viruses
Recombination
Sequences
Phylogenies
title_short Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_full Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_fullStr Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_full_unstemmed Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
title_sort Dynamics of Molecular Evolution and Phylogeography of Barley yellow dwarf virus-PAV
dc.creator.none.fl_str_mv Wu, Beilei
Blanchard-Letort, Alexandra
Liu, Yan
Zhou, Guanghe
Wang, Xifeng
Elena, Santiago F.
author Wu, Beilei
author_facet Wu, Beilei
Blanchard-Letort, Alexandra
Liu, Yan
Zhou, Guanghe
Wang, Xifeng
Elena, Santiago F.
author_role author
author2 Blanchard-Letort, Alexandra
Liu, Yan
Zhou, Guanghe
Wang, Xifeng
Elena, Santiago F.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Plant RNA viruses
Recombination
Sequences
Phylogenies
topic Plant RNA viruses
Recombination
Sequences
Phylogenies
description Barley yellow dwarf virus (BYDV) species PAV occurs frequently in irrigated wheat fields worldwide and can be efficiently transmitted by aphids. Isolates of BYDV-PAV from different countries show great divergence both in genomic sequences and pathogenicity. Despite its economical importance, the genetic structure of natural BYDV-PAV populations, as well as of the mechanisms maintaining its high diversity, remain poorly explored. In this study, we investigate the dynamics of BYDVPAV genome evolution utilizing time-structured data sets of complete genomic sequences from 58 isolates from different hosts obtained worldwide. First, we observed that BYDV-PAV exhibits a high frequency of homologous recombination. Second, our analysis revealed that BYDV-PAV genome evolves under purifying selection and at a substitution rate similar to other RNA viruses (3.15861024 nucleotide substitutions/site/year). Phylogeography analyses show that the diversification of BYDV-PAV can be explained by local geographic adaptation as well as by host-driven adaptation. These results increase our understanding of the diversity, molecular evolutionary characteristics and epidemiological properties of an economically important plant RNA virus.
publishDate 2011
dc.date.none.fl_str_mv 2011
2012
2012
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/47814
url http://hdl.handle.net/10261/47814
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
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