Chemotherapy after immunotherapy failure in patients with advanced gastrointestinal tumors

First line therapies usually induce the longest progression free survival (PFS) in metastatic gastrointestinal cancers (GIC) as compared to subsequent lines of treatment. However, immunotherapy (IT) due to its mechanisms of action could influence sensitivity to conventional cancer therapy (CCT) afte...

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Detalles Bibliográficos
Autores: Baraibar-Argota, I. (Iosune)|||/items/7e21232f-3890-4d16-901d-006ef5420eb1, Martin-Romano, P. (Patricia)|||/items/d5da8b9c-e6c8-4e0a-9ab8-300dd23a5df2, Fernández-de-Sanmamed-Gutiérrez, M. (Miguel)|||/items/35ac602c-f0ff-4664-bbd2-506afc96db09, Rodriguez-Ruiz, M.E. (María Esperanza)|||/items/bb89f8c4-6380-4de3-8dd0-877dbf28ef44, Melero, I. (Ignacio)|||/items/82113ea8-7ce1-49d5-9ee3-42cf20db1c4e, Resano, L. (Leyre)|||/items/31b6e030-b78a-4b56-93c2-7d811832e718, Ortega-Montes, A. (Ana)|||/items/99a6623e-27c7-4d74-9cf7-fe57e11c99bf, Ponz-Sarvise, M. (Mariano)|||/items/2439c580-068e-431b-a20d-bdeab1b7c3ad, Castañón-Álvarez, E. (Eduardo)|||/items/6ef1df2b-d729-4ca8-af2e-dd81758ddd7a
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/65316
Acceso en línea:https://hdl.handle.net/10171/65316
Access Level:acceso abierto
Palabra clave:Progression free survival (PFS)
Gastrointestinal cancers (GIC)
Descripción
Sumario:First line therapies usually induce the longest progression free survival (PFS) in metastatic gastrointestinal cancers (GIC) as compared to subsequent lines of treatment. However, immunotherapy (IT) due to its mechanisms of action could influence sensitivity to conventional cancer therapy (CCT) after progression to IT and thereby, influence both tumor growth rate (TGR) and PFS. We have studied TGR and PFS before and after participation in phase I IT trials.

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