Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?

The interindividual variability is an increasingly global problem when treating patients from different backgrounds with diverse customs, metabolism, and necessities. Dose adjustment is frequently based on empirical methods, and therefore, the chance of undesirable side effects to occur is high. Thr...

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Detalles Bibliográficos
Autores: Konta, Andrea Alice, García Piña, Marta, Serrano López, Dolores Remedios
Tipo de recurso: artículo
Fecha de publicación:2017
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/19207
Acceso en línea:https://hdl.handle.net/20.500.14352/19207
Access Level:acceso abierto
Palabra clave:3D printing
drug delivery
personalised medicine
polymers
FDM
SLA
Farmacología (Medicina)
Farmacología (Farmacia)
Medicamentos
3209 Farmacología
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spelling Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?Konta, Andrea AliceGarcía Piña, MartaSerrano López, Dolores Remedios3D printingdrug deliverypersonalised medicinepolymersFDMSLAFarmacología (Medicina)Farmacología (Farmacia)Medicamentos3209 FarmacologíaThe interindividual variability is an increasingly global problem when treating patients from different backgrounds with diverse customs, metabolism, and necessities. Dose adjustment is frequently based on empirical methods, and therefore, the chance of undesirable side effects to occur is high. Three-dimensional (3D) Printed medicines are revolutionsing the pharmaceutical market as potential tools to achieve personalised treatments adapted to the specific requirements of each patient, taking into account their age, weight, comorbidities, pharmacogenetic, and pharmacokinetic characteristics. Additive manufacturing or 3D printing consists of a wide range of techniques classified in many categories but only three of them are mostly used in the 3D printing of medicines: printing-based inkjet systems, nozzle-based deposition systems, and laser-based writing systems. There are several drawbacks when using each technique and also the type of polymers readily available do not always possess the optimal properties for every drug. The aim of this review is to give an overview about the current techniques employed in 3D printing medicines, highlighting their advantages, disadvantages, along with the polymer and drug requirements for a successful printing. The major application of these techniques will be also discussed.MDPIUniversidad Complutense de Madrid20172017-09-2220172017-09-22journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.14352/19207reponame:Docta Complutenseinstname:Universidad Complutense de Madrid (UCM)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccessoai:docta.ucm.es:20.500.14352/192072026-06-02T12:44:21Z
dc.title.none.fl_str_mv Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
title Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
spellingShingle Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
Konta, Andrea Alice
3D printing
drug delivery
personalised medicine
polymers
FDM
SLA
Farmacología (Medicina)
Farmacología (Farmacia)
Medicamentos
3209 Farmacología
title_short Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
title_full Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
title_fullStr Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
title_full_unstemmed Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
title_sort Personalised 3D Printed Medicines: Which Techniques and Polymers Are More Successful?
dc.creator.none.fl_str_mv Konta, Andrea Alice
García Piña, Marta
Serrano López, Dolores Remedios
author Konta, Andrea Alice
author_facet Konta, Andrea Alice
García Piña, Marta
Serrano López, Dolores Remedios
author_role author
author2 García Piña, Marta
Serrano López, Dolores Remedios
author2_role author
author
dc.contributor.none.fl_str_mv Universidad Complutense de Madrid
dc.subject.none.fl_str_mv 3D printing
drug delivery
personalised medicine
polymers
FDM
SLA
Farmacología (Medicina)
Farmacología (Farmacia)
Medicamentos
3209 Farmacología
topic 3D printing
drug delivery
personalised medicine
polymers
FDM
SLA
Farmacología (Medicina)
Farmacología (Farmacia)
Medicamentos
3209 Farmacología
description The interindividual variability is an increasingly global problem when treating patients from different backgrounds with diverse customs, metabolism, and necessities. Dose adjustment is frequently based on empirical methods, and therefore, the chance of undesirable side effects to occur is high. Three-dimensional (3D) Printed medicines are revolutionsing the pharmaceutical market as potential tools to achieve personalised treatments adapted to the specific requirements of each patient, taking into account their age, weight, comorbidities, pharmacogenetic, and pharmacokinetic characteristics. Additive manufacturing or 3D printing consists of a wide range of techniques classified in many categories but only three of them are mostly used in the 3D printing of medicines: printing-based inkjet systems, nozzle-based deposition systems, and laser-based writing systems. There are several drawbacks when using each technique and also the type of polymers readily available do not always possess the optimal properties for every drug. The aim of this review is to give an overview about the current techniques employed in 3D printing medicines, highlighting their advantages, disadvantages, along with the polymer and drug requirements for a successful printing. The major application of these techniques will be also discussed.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-09-22
2017
2017-09-22
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.14352/19207
url https://hdl.handle.net/20.500.14352/19207
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 3.0 España
https://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Docta Complutense
instname:Universidad Complutense de Madrid (UCM)
instname_str Universidad Complutense de Madrid (UCM)
reponame_str Docta Complutense
collection Docta Complutense
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.300724

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