Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain

Background: Pressurized metered-dose inhalers (pMDIs) exert an environmental impact resulting from CO2 emissions. Therapeutic alternatives with less environmental impact are widely used. Nevertheless, the choice of device and appropriate therapy should meet the clinical needs and the characteristics...

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Detalhes bibliográficos
Autores: Montoro Lacomba, Javier, Antolín-Amérigo, D., Izquierdo-Domínguez, A., Zapata, J. J., González, G., Valero, A.
Formato: artículo
Fecha de publicación:2023
País:España
Recursos:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/5177
Acesso em linha:http://hdl.handle.net/20.500.12466/5177
Access Level:acceso abierto
Palavra-chave:Asthma
Inhaler devices
Metered-dose inhalers
Antiasthmatic agents
Carbon footprint
Climate change
Global warming
Environment
Asma
Dispositivos inhaladores
Inhaladores de dosis medidas
Agentes antiasmáticos
Huella de carbono
Cambio climático
Calentamiento global
Medio ambiente
3207.01 Alergias
2412 Inmunología
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spelling Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in SpainMontoro Lacomba, JavierAntolín-Amérigo, D.Izquierdo-Domínguez, A.Zapata, J. J.González, G.Valero, A.AsthmaInhaler devicesMetered-dose inhalersAntiasthmatic agentsCarbon footprintClimate changeGlobal warmingEnvironmentAsmaDispositivos inhaladoresInhaladores de dosis medidasAgentes antiasmáticosHuella de carbonoCambio climáticoCalentamiento globalMedio ambiente3207.01 Alergias2412 InmunologíaBackground: Pressurized metered-dose inhalers (pMDIs) exert an environmental impact resulting from CO2 emissions. Therapeutic alternatives with less environmental impact are widely used. Nevertheless, the choice of device and appropriate therapy should meet the clinical needs and the characteristics of the patient. Objective: The primary objective was to estimate the impact of pMDIs prescribed for any indication on annual CO2 emissions in Spain. The secondary objective was to evaluate the potential impact of switching pMDIs to dry-powder inhalers (DPIs) in patients with asthma. Methods: A systematic review of the evidence published during 2010-2021 was carried out. Average annual CO2 emissions of DPIs and pMDIs were calculated in 2 scenarios: the current situation and a hypothetical situation involving a switch from all pMDIs to DPIs. The impact of the switch on clinical outcomes was also evaluated. Results: The total value of CO2-eq/year due to DPIs and pMDIs accounted for 0.0056% and 0.0909%, respectively, of total emissions in Spain. In the event of switching pMDIs to DPIs, except those used for rescue medication, the percentages were 0.0076% and 0.0579%. The evaluation of efficacy, handling, satisfaction, safety, and use of health care resources was not conclusive. Conclusions: Current CO2 emissions by pMDIs account for a small percentage of the total CO2 footprint in Spain. Nevertheless, there is a need for research into new and more sustainable devices. Suitability and patient clinical criteria such as age and inspiratory flow should be prioritized when prescribing an inhaler20252025-01-1620232023-01-0120232023-01-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/20.500.12466/5177reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártirinstname:Universidad Católica de Valencia San Vicente MártirInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:riucv.ucv.es:20.500.12466/51772026-06-19T08:32:07Z
dc.title.none.fl_str_mv Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
title Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
spellingShingle Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
Montoro Lacomba, Javier
Asthma
Inhaler devices
Metered-dose inhalers
Antiasthmatic agents
Carbon footprint
Climate change
Global warming
Environment
Asma
Dispositivos inhaladores
Inhaladores de dosis medidas
Agentes antiasmáticos
Huella de carbono
Cambio climático
Calentamiento global
Medio ambiente
3207.01 Alergias
2412 Inmunología
title_short Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
title_full Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
title_fullStr Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
title_full_unstemmed Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
title_sort Impact of Asthma Inhalers on Global Climate: A Systematic Review of Their Carbon Footprint and Clinical Outcomes in Spain
dc.creator.none.fl_str_mv Montoro Lacomba, Javier
Antolín-Amérigo, D.
Izquierdo-Domínguez, A.
Zapata, J. J.
González, G.
Valero, A.
author Montoro Lacomba, Javier
author_facet Montoro Lacomba, Javier
Antolín-Amérigo, D.
Izquierdo-Domínguez, A.
Zapata, J. J.
González, G.
Valero, A.
author_role author
author2 Antolín-Amérigo, D.
Izquierdo-Domínguez, A.
Zapata, J. J.
González, G.
Valero, A.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Asthma
Inhaler devices
Metered-dose inhalers
Antiasthmatic agents
Carbon footprint
Climate change
Global warming
Environment
Asma
Dispositivos inhaladores
Inhaladores de dosis medidas
Agentes antiasmáticos
Huella de carbono
Cambio climático
Calentamiento global
Medio ambiente
3207.01 Alergias
2412 Inmunología
topic Asthma
Inhaler devices
Metered-dose inhalers
Antiasthmatic agents
Carbon footprint
Climate change
Global warming
Environment
Asma
Dispositivos inhaladores
Inhaladores de dosis medidas
Agentes antiasmáticos
Huella de carbono
Cambio climático
Calentamiento global
Medio ambiente
3207.01 Alergias
2412 Inmunología
description Background: Pressurized metered-dose inhalers (pMDIs) exert an environmental impact resulting from CO2 emissions. Therapeutic alternatives with less environmental impact are widely used. Nevertheless, the choice of device and appropriate therapy should meet the clinical needs and the characteristics of the patient. Objective: The primary objective was to estimate the impact of pMDIs prescribed for any indication on annual CO2 emissions in Spain. The secondary objective was to evaluate the potential impact of switching pMDIs to dry-powder inhalers (DPIs) in patients with asthma. Methods: A systematic review of the evidence published during 2010-2021 was carried out. Average annual CO2 emissions of DPIs and pMDIs were calculated in 2 scenarios: the current situation and a hypothetical situation involving a switch from all pMDIs to DPIs. The impact of the switch on clinical outcomes was also evaluated. Results: The total value of CO2-eq/year due to DPIs and pMDIs accounted for 0.0056% and 0.0909%, respectively, of total emissions in Spain. In the event of switching pMDIs to DPIs, except those used for rescue medication, the percentages were 0.0076% and 0.0579%. The evaluation of efficacy, handling, satisfaction, safety, and use of health care resources was not conclusive. Conclusions: Current CO2 emissions by pMDIs account for a small percentage of the total CO2 footprint in Spain. Nevertheless, there is a need for research into new and more sustainable devices. Suitability and patient clinical criteria such as age and inspiratory flow should be prioritized when prescribing an inhaler
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-01-01
2023
2023-01-01
2025
2025-01-16
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12466/5177
url http://hdl.handle.net/20.500.12466/5177
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.source.none.fl_str_mv reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
instname:Universidad Católica de Valencia San Vicente Mártir
instname_str Universidad Católica de Valencia San Vicente Mártir
reponame_str RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
collection RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812455

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