A wearable closed-loop insulin delivery system based on low-power SoCs
The number of patients living with diabetes has increased significantly in recent years due to several factors. Many of these patients are choosing to use insulin pumps for their treatment, artificial systems that administer their insulin and consist of a glucometer and an automatic insulin supply w...
| Autores: | , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2019 |
| País: | España |
| Institución: | Universidad de Alcalá (UAH) |
| Repositorio: | e_Buah Biblioteca Digital Universidad de Alcalá |
| Idioma: | inglés |
| OAI Identifier: | oai:ebuah.uah.es:10017/60001 |
| Acceso en línea: | http://hdl.handle.net/10017/60001 https://dx.doi.org/10.3390/electronics8060612 |
| Access Level: | acceso abierto |
| Palabra clave: | Insulin delivery Wearable system Closed-loop Embedded platform Electrónica Electronics |
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A wearable closed-loop insulin delivery system based on low-power SoCsBerián Múgica, JesúsBravo Muñoz, Ignacio|||0000-0002-6964-0036Gardel Vicente, Alfredo|||0000-0001-7887-4689Lázaro Galilea, José Luis|||0000-0001-5048-7134Hernández, SergioInsulin deliveryWearable systemClosed-loopEmbedded platformElectrónicaElectronicsThe number of patients living with diabetes has increased significantly in recent years due to several factors. Many of these patients are choosing to use insulin pumps for their treatment, artificial systems that administer their insulin and consist of a glucometer and an automatic insulin supply working in an open loop. Currently, only a few closed-loop insulin delivery devices are commercially available. The most widespread systems among patients are what have been called the “Do-It-Yourself Hybrid Closed-Loop systems.” These systems require the use of platforms with high computing power. In this paper, we will present a novel wearable system for insulin delivery that reduces the energy and computing consumption of the platform without affecting the computation requirements. Patients’ information is obtained from a commercial continuous glucose sensor and a commercial insulin pump operating in a conventional manner. An ad-hoc embedded system will connect with the pump and the sensor to collect the glucose data and process it. That connection is accomplished through a radiofrequency channel that provides a suitable system for the patient. Thus, this system does not require to be connected to any other processor, which increases the overall stability. Using parameters configured by the patient, the control system will make automatic adjustments in the basal insulin infusion thereby bringing the patient’s glycaemia to the target set by a doctor’s prescription. The results obtained will be satisfactory as long as the configured parameters faithfully match the specific characteristics of the patient. Results from the simulation of 30 virtual patients (10 adolescents, 10 adults, and 10 children), using a python implementation of the FDA-approved (Food and Drug Administration) UVa (University of Virginia)/Padova Simulator and a python implementation of the proposed algorithm, are presented.MDPI20192019-05-31journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10017/60001https://dx.doi.org/10.3390/electronics8060612reponame:e_Buah Biblioteca Digital Universidad de Alcaláinstname:Universidad de Alcalá (UAH)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:ebuah.uah.es:10017/600012026-06-18T11:13:07Z |
| dc.title.none.fl_str_mv |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| title |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| spellingShingle |
A wearable closed-loop insulin delivery system based on low-power SoCs Berián Múgica, Jesús Insulin delivery Wearable system Closed-loop Embedded platform Electrónica Electronics |
| title_short |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| title_full |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| title_fullStr |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| title_full_unstemmed |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| title_sort |
A wearable closed-loop insulin delivery system based on low-power SoCs |
| dc.creator.none.fl_str_mv |
Berián Múgica, Jesús Bravo Muñoz, Ignacio|||0000-0002-6964-0036 Gardel Vicente, Alfredo|||0000-0001-7887-4689 Lázaro Galilea, José Luis|||0000-0001-5048-7134 Hernández, Sergio |
| author |
Berián Múgica, Jesús |
| author_facet |
Berián Múgica, Jesús Bravo Muñoz, Ignacio|||0000-0002-6964-0036 Gardel Vicente, Alfredo|||0000-0001-7887-4689 Lázaro Galilea, José Luis|||0000-0001-5048-7134 Hernández, Sergio |
| author_role |
author |
| author2 |
Bravo Muñoz, Ignacio|||0000-0002-6964-0036 Gardel Vicente, Alfredo|||0000-0001-7887-4689 Lázaro Galilea, José Luis|||0000-0001-5048-7134 Hernández, Sergio |
| author2_role |
author author author author |
| dc.subject.none.fl_str_mv |
Insulin delivery Wearable system Closed-loop Embedded platform Electrónica Electronics |
| topic |
Insulin delivery Wearable system Closed-loop Embedded platform Electrónica Electronics |
| description |
The number of patients living with diabetes has increased significantly in recent years due to several factors. Many of these patients are choosing to use insulin pumps for their treatment, artificial systems that administer their insulin and consist of a glucometer and an automatic insulin supply working in an open loop. Currently, only a few closed-loop insulin delivery devices are commercially available. The most widespread systems among patients are what have been called the “Do-It-Yourself Hybrid Closed-Loop systems.” These systems require the use of platforms with high computing power. In this paper, we will present a novel wearable system for insulin delivery that reduces the energy and computing consumption of the platform without affecting the computation requirements. Patients’ information is obtained from a commercial continuous glucose sensor and a commercial insulin pump operating in a conventional manner. An ad-hoc embedded system will connect with the pump and the sensor to collect the glucose data and process it. That connection is accomplished through a radiofrequency channel that provides a suitable system for the patient. Thus, this system does not require to be connected to any other processor, which increases the overall stability. Using parameters configured by the patient, the control system will make automatic adjustments in the basal insulin infusion thereby bringing the patient’s glycaemia to the target set by a doctor’s prescription. The results obtained will be satisfactory as long as the configured parameters faithfully match the specific characteristics of the patient. Results from the simulation of 30 virtual patients (10 adolescents, 10 adults, and 10 children), using a python implementation of the FDA-approved (Food and Drug Administration) UVa (University of Virginia)/Padova Simulator and a python implementation of the proposed algorithm, are presented. |
| publishDate |
2019 |
| dc.date.none.fl_str_mv |
2019 2019-05-31 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 NA http://purl.org/coar/version/c_be7fb7dd8ff6fe43 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10017/60001 https://dx.doi.org/10.3390/electronics8060612 |
| url |
http://hdl.handle.net/10017/60001 https://dx.doi.org/10.3390/electronics8060612 |
| dc.language.none.fl_str_mv |
Inglés eng |
| language_invalid_str_mv |
Inglés |
| language |
eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
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application/pdf |
| dc.publisher.none.fl_str_mv |
MDPI |
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MDPI |
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reponame:e_Buah Biblioteca Digital Universidad de Alcalá instname:Universidad de Alcalá (UAH) |
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Universidad de Alcalá (UAH) |
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e_Buah Biblioteca Digital Universidad de Alcalá |
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e_Buah Biblioteca Digital Universidad de Alcalá |
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